June 2024 in “British Journal of Dermatology” This study found that alopecia areata significantly impacts patients' quality of life irrespective of hair loss severity, and concluded that the newer assessment tools AAPPO and AASIS better capture this impact compared to the traditional SALT measure.
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2 citations
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November 2024 in “World Journal of Psychiatry” In this study, researchers found that wound size, anxiety, and depression significantly impact the effectiveness of treatments for chronic wounds, identifying these factors as independent risks for poor therapeutic outcomes.
July 2026 in “Journal of the American Academy of Dermatology” 51 citations
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December 2017 in “Skin Appendage Disorders” This review examines the literature on autoimmune hair loss disorders, highlighting the collapse of immune privilege and the potential role of neurogenic stress in this process, but reports no new clinical results.
9 citations
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January 2001 in “Dermatology” This study reports two cases where pili anulati, typically a non-fragile hair condition, showed increased fragility due to androgenetic alopecia, causing hair shaft fracturing in the affected area.
17 citations
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May 2016 in “Journal of Psychosomatic Research” This study observed that in patients with androgenetic alopecia, illness perception was linked to higher psychological distress and lower quality of life compared to those with alopecia areata.
September 2022 in “IP Indian journal of clinical and experimental dermatology” This case report describes an 8-year-old girl with atrichia congenita characterized by complete hair loss and papular lesions, attributed to an insertion mutation in the hairless gene.
20 citations
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November 2013 in “The Open Cancer Journal” This observational study provides cause-specific mortality estimates to help patients and physicians better understand long-term outcomes for localized prostate cancer based on initial treatment choices.
44 citations
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August 2010 in “Journal of Investigative Dermatology” Alopecia areata seriously lowers quality of life, especially affecting self-image, mental health, and social life.
May 2017 in “Chinese Journal of Dermatology” This study reported that alopecia can moderately impact patients' quality of life and is linked to a depressive tendency, with frequent medical visits and higher quality of life impairment as risk factors.
2 citations
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July 2024 in “Revista Ibero-Americana de Humanidades, Ciências e Educação” This study found that alopecia areata presents diverse hair loss patterns and a range of treatment options, though no treatment was universally effective, and significantly impacts patients' psychological well-being.
128 citations
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February 2016 in “British Journal of Dermatology” This study found that patients with alopecia areata experience significant impairments in health-related quality of life, notably affecting mental health, according to various quality of life assessment tools.
January 2015 in “Faculty of 1000 Research Ltd” Androgenetic alopecia may be irreversible due to the detachment of a muscle from hair follicles.
January 2005 in “International Society of Hair Restoration Surgery” This article reviews the psychological impact of androgenetic alopecia and emphasizes the importance of supporting patients with its effects, but presents no new findings.
March 2024 in “CRC Press eBooks” This article discusses the psychosocial impact of androgenetic alopecia and does not report new findings; it highlights the perceived effects of hair loss on self-esteem and confidence.
52 citations
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October 1997 in “American Journal of Psychiatry” This discussion reviews the complexities of trichotillomania's symptoms, pathology, and treatment, but reports no new research findings; it highlights a specific illustrative case.
March 2005 in “Journal of the American Academy of Dermatology” This study found that hair loss impairs quality of life differently for men and women in France, affecting men's physical health and women's mental health more significantly.
1 citations
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November 2025 in “Journal of Health Psychology” This study found that individuals with Alopecia Areata experience significantly higher social appearance anxiety compared to healthy controls, driven more by appearance-related concerns than by general anxiety or depression, highlighting the importance of targeted psychosocial assessments in their routine care.
25 citations
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December 2015 in “Journal of the European Academy of Dermatology and Venereology” This study found that alopecia areata negatively affects patients' quality of life, though less severely than psoriasis, atopic dermatitis, and onychomycosis.
2 citations
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September 2015 in “Dicle Medical Journal” This study found that women with diffuse alopecia exhibited higher anxiety and depression scores compared to controls, suggesting a bidirectional relationship between alopecia and psychological symptoms.
16 citations
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November 2015 in “International Journal of Dermatology” This study found that alopecia significantly reduces quality of life among South African Black women, with subjective symptoms and self-image concerns having the greatest impact.
9 citations
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November 2022 in “JAAD International” This study found that patients with alopecia areata face challenges like medical uncertainty and lack of information, highlighting the need for reliable and accessible treatment information that aligns with their preferences.
1 citations
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February 2021 in “International Journal of Research in Dermatology” This study found that premature graying significantly impacts the quality of life among affected individuals, reporting profound effects on psychological and social well-being, including guilt and mood fluctuations.
1 citations
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June 2025 in “Journal of Patient Experience” This study found that Finnish individuals with alopecia areata, especially those with significant hair loss, reported reduced well-being and significant comorbidities, highlighting unmet needs for treatment and professional support.
March 2021 in “Journal of The European Academy of Dermatology and Venereology” Low quality of life and high HSS-29 scores increase risk of losing patients during treatment.
28 citations
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January 2015 in “Journal of Cell Science” In this study, PINCH-1 gene loss in mouse epidermis led to detachment from the basement membrane, thickened skin, and hair loss, with findings suggesting PINCH-1 plays a role in keratinocyte adhesion through both ILK and EPLIN pathways.
31 citations
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October 2002 in “Journal of Investigative Dermatology” IL-10 may worsen alopecia areata instead of helping it.
4 citations
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September 2012 in “Transplant international” Graft rejection in a hand transplant may trigger hair loss due to autoimmune responses.
86 citations
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May 2011 in “Journal of The American Academy of Dermatology” This study found that patients with alopecia perceive their hair loss as more severe than dermatologists do, and their own ratings of hair loss severity better reflect their quality of life impacts.