380 citations
,
March 2000 in “Proceedings of the National Academy of Sciences” This study demonstrates that mice with ectopic expression of the human GLI-1 gene in their skin developed tumors resembling human basal cell carcinoma, suggesting that GLI-1 is central to tumor development without additional p53 or Ha ras mutations.
190 citations
,
July 2006 in “Experimental Dermatology” This review discusses the role of the sonic hedgehog pathway in skin development and cancer, highlighting its potential as a target for chemoprevention and treatment; it reports no new findings.
55 citations
,
December 1987 in “Archives of Dermatology” This review discusses two genetic disorders affecting biotin metabolism, each resulting in distinctive skin and hair manifestations, and outlines the associated serious metabolic complications.
46 citations
,
November 2014 in “Journal of Cutaneous Pathology” This study describes the diverse histopathological patterns and clinical features observed in patients with folliculotropic mycosis fungoides, emphasizing the importance of accurate recognition to avoid diagnostic errors.
36 citations
,
June 2018 in “Journal of The American Academy of Dermatology” This review examines the increasing clinical applications of dermoscopy in diagnosing various skin conditions and highlights its potential to improve diagnostic accuracy and reduce unnecessary histologic confirmation.
33 citations
,
April 2020 in “Dermatitis” This study found that 9% of tested patients had positive patch test reactions linked to hair care products, with most reactions clinically relevant and commonly involving allergens like p-phenylenediamine.
32 citations
,
May 1995 in “Contact Dermatitis” This article reviews previous cases and reports of allergic contact dermatitis from minoxidil but does not provide new clinical findings.
28 citations
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January 2017 in “Indian Dermatology Online Journal” In this study, skin manifestations such as hirsutism and acne were prevalent among women with PCOS, highlighting their importance in diagnosis and symptomatology.
24 citations
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January 2014 in “PubMed” This case report suggests that topical imiquimod cream may be an effective alternative treatment for generalized discoid lupus erythematosus without systemic involvement.
17 citations
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May 1998 in “Contact Dermatitis” Minoxidil can cause pustular allergic reactions on skin.
16 citations
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July 1994 in “Journal of Dermatological Science” This study found that minoxidil sulfate and pinacidil did not activate K channel currents in hair follicles, suggesting their effect on hair growth might occur through other mechanisms like increased blood flow.
16 citations
,
July 1996 in “Dermatologic Clinics” This article discusses common dermatologic side effects of psychopharmacologic agents such as eruptions, urticaria, and photosensitivity, but it reports no new research findings.
11 citations
,
October 2016 in “Pediatric dermatology” This case study observed that three girls with alopecia experienced complete hair regrowth after avoiding balsam of Peru and related fragrances, suggesting contact allergy played a role in their hair loss.
11 citations
,
January 2000 in “Der Hautarzt” This review describes how male hypogonadism can lead to various skin and hair symptoms, as well as potential dermatological reactions to hormone treatments and reports no new clinical results.
9 citations
,
March 1968 in “The BMJ” In their 1957 study, Neuman and Neuman suggested that magnesium deficiency may inhibit the ion exchange process required for calcium ions to enter extracellular fluid, potentially affecting calcium mobilization.
8 citations
,
January 2009 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” This study reports a novel TRbeta gene mutation associated with resistance to thyroid hormone syndrome, which may contribute to various forms of alopecia in the affected family members.
7 citations
,
July 2019 in “The Journal of Dermatology” This case report describes an 18-year-old male with kerion celsi from Trichophyton tonsurans infection whose condition improved with terbinafine treatment, and highlights that although IL-17A expression increased in skin lesions, it was associated with disrupted antimicrobial peptide expression and severe inflammation, causing tissue damage.
5 citations
,
January 2017 in “Skin appendage disorders” In this case report, the authors linked acute psoriasiform contact dermatitis of the forehead and scalp to a low-laser light cap, identifying DMDE in the fabric as a likely cause.
4 citations
,
January 2019 in “PubMed” This study found that women with female pattern hair loss had significant hormonal imbalances, specifically involving adrenal androgens, suggesting these may play a central role in the condition's development.
3 citations
,
September 2017 in “Pediatric Dermatology” This article discusses contact dermatitis linked to alopecia and hyperpigmentation, but it reports no new clinical results.
3 citations
,
March 2017 in “Case Reports in Dermatology” This case report describes a 26-year-old with systemic lupus erythematosus presenting with psoriatic alopecia, revealing a novel scalp dermoscopic pattern of “patchy dotted vessels.
1 citations
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January 2022 in “Annals of Dermatology” In this case report, researchers identified a novel homozygous missense mutation in the MBTPS2 gene associated with the mild form of IFAP syndrome in a 7-year-old boy.
1 citations
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September 2015 in “Clinics in Dermatology” This article offers a question-by-question guide to assist clinicians in diagnosing hair shaft disorders, presenting no new clinical results.
1 citations
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June 2013 in “Medicine” This article reviews how to take a thorough dermatological history, conduct examinations, and discusses diagnostic tools; it reports no new clinical findings.
1 citations
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December 2022 in “Gynecological Endocrinology” This study found that among women with PCOS, higher HOMA-IR levels were associated with acanthosis nigricans, and increased DHEA-SO4, FAI, and FI values were linked to hirsutism.
1 citations
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June 2021 in “Journal of gynecology and womens health” This study found that the prevalence of polycystic ovarian syndrome among women of reproductive age in urban and rural areas of Hyderabad, Telangana, is between 6.5% and 6.8%.
1 citations
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October 2020 in “International Journal of Research in Dermatology” This study found that short vellus hair and yellow dots are common dermoscopic findings in alopecia areata, with variations indicating disease activity or remission.
1 citations
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September 2017 in “BMJ” The man has a disease causing skin patches, thickened nerves, and mild muscle weakness.
May 2026 in “Bioactive Materials” This study reported that in degenerative alopecia, Zn²⁺/Cu²⁺-dependent proteases are downregulated and destabilized, and a specially developed microneedle patch reactivated these enzymes, reduced senescence, and enhanced hair regeneration in an animal model.
December 2025 in “Dermatological Health” This case report describes how a 23-year-old woman experienced eyebrow thinning and hair loss linked to cosmetic use, with diagnostic tests confirming follicular damage. Discontinuing the product led to eyebrow regrowth, highlighting potential risks from cosmetics and the value of non-invasive diagnostics for evaluation.