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Smad-4 and Smad-7 are key in hair follicle development, with other Smads being less important.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

Researchers found 71 genetic regions linked to male pattern baldness, which account for 38% of its genetic risk.

Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.

Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.

Nearly all elderly nursing home residents had a skin disease, with dry skin being the most common.

K16 can partially replace K14 but causes hair loss and skin issues.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.

MRL/MpJ mice's skin wounds heal with scars, unlike their ear wounds which can regenerate.

South Asian women with PCOS experience more psychological distress and have a poorer quality of life, especially in social relationships, with hirsutism affecting them more than obesity.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.

Minoxidil doesn't increase pericardial disorder risk, but may cause fluid accumulation.

The conclusion is to use scalp cooling, gentle hair care, and treatments like minoxidil for managing hair loss from chemotherapy, and stresses the need for more research and collaboration in this area.

Researchers created rat liver stem cells that could help repair liver failure in rats and may be useful for studying human liver diseases.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.

Keratin peptides can change hair shape gently without harsh chemicals.

Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.

The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.

Hair loss in balding individuals is linked to changes in specific hair growth-related genes.

Genes play a significant role in male-pattern baldness, and understanding them could lead to new treatments and insights into related health issues.

Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.

Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.

Finasteride reduces Tourette syndrome symptoms, but results may be limited due to potential biases.

Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.