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This review details the process and advantages of drug repurposing, highlighting its potential as a cost-effective and expedited alternative to traditional drug development while summarizing various strategies and successful examples, and exploring related regulatory challenges.

The authors describe drug repurposing as a promising strategy for finding new uses for existing drugs, noting it is efficient, cost-effective, and poses lower risks than traditional drug discovery processes, potentially aiding in the treatment of rare and difficult-to-treat diseases.

This article provides regulatory updates, legal briefs, and industry news, reporting no new clinical findings.

This review highlights the potential of drug repurposing to offer faster and more cost-effective solutions compared to traditional drug development methods by leveraging existing medications for new uses; however, regulatory and intellectual property challenges remain significant barriers.

This study found that independent pharmacies in the St. Louis area offer significantly lower prices for tamsulosin and oxybutynin ER compared to chain pharmacies, while zip-code and median income show no pricing correlation.

This source discusses the growing trend of drug repurposing, a strategy that seeks new uses for existing drugs to overcome challenges like lengthy timelines and high costs in the traditional drug development process.

This article examines why a major health care system's patients cannot access Wal-Mart's low price for finasteride, despite broader availability, due to complex industry and policy factors, without reporting new clinical results.

This study observed that the out-of-pocket prices for generic medications used to treat benign prostatic hyperplasia can vary by up to 500% among pharmacies in the Pittsburgh area, with chain pharmacies pricing significantly higher than independents.

This review discusses the process and advantages of drug repurposing, highlighting its potential to expedite development and improve therapeutic outcomes with examples like sildenafil and metformin.

This review discusses drug repurposing for various conditions, including cancer and COVID-19, highlighting ongoing trials with potential repurposed drugs but provides no new clinical results.

This review discusses drug repurposing strategies for rare diseases, highlighting methodologies, achievements, and challenges, but reports no new clinical results.

A medicine company has recalled a drug because it contained an unlisted blood pressure medication.

Actemra is approved for a specific artery condition, HIV treatment adherence has improved, women may pay more for a hair loss product, and incorrect dosing of blood thinners can be risky.

This source discusses drug repurposing, which seeks new therapeutic uses for existing drugs, emphasizing its benefits like faster development, reduced costs, and novel treatments for unmet medical needs. The chapter outlines current trends and future perspectives in drug discovery through repurposed drugs.

This review highlights that drug repositioning offers a cost-effective alternative to traditional drug discovery, especially for treating orphan and resistant diseases like COVID-19, by repurposing existing drugs such as Hydroxychloroquine and Remdesivir.

This systematic review synthesizes the current state of drug repurposing, revealing its potential in various therapeutic areas like oncology and infectious diseases through insights from mechanistic studies and real-world evidence, and discusses emerging tools and challenges in the field.

This article discusses the challenges and considerations in drug repurposing, particularly the importance of dose finding studies when adapting drugs for new indications, and reports no new clinical results.

This review discusses the off-label use of drugs like Minoxidil, Aripripazole, and others, providing insights for physicians and pharmacists but reports no new clinical findings.

New drugs for Alzheimer's and rheumatoid arthritis advanced, a Zika vaccine is in development, and there were business deals in anesthesia and oncology.

This study highlights the approval of orforglipron under the FDA's National Priority Voucher program, emphasizing its significance as a convenient oral treatment option with beneficial effects on glycemic and lipid profiles for diabetes and obesity management.

This review outlines drug repurposing as an efficient, low-cost strategy to identify new uses for existing drugs, highlighting various computational and experimental approaches as well as publicly available databases to aid in personalized pharmacotherapy.

This review examines the current landscape of drug repositioning, highlighting that computational methods expand possibilities for reusing existing drugs to treat unmet medical needs. The authors discuss both the potential of these methods and the challenges faced in identifying new therapeutic applications.