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    Glossary Genetic Overlap

    shared genetic factors influence multiple traits or conditions

    Genetic Overlap refers to the phenomenon where different traits or conditions share common genetic factors. For example, certain genes might influence both hair growth and susceptibility to alopecia, meaning that individuals with specific genetic markers might be more likely to experience both traits. This concept is important in understanding how complex traits and diseases can be interconnected at the genetic level.

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    1. Exploring the overlap between alopecia areata and major depressive disorder: Epidemiological and genetic perspectives Journal of the European Academy of Dermatology and Venereology · 2023 · 9 citations
    2. Short anagen hair syndrome: association with mono- and biallelic variants in <i>WNT10A</i> and a genetic overlap with male pattern hair loss British Journal of Dermatology · 2023
    3. Short anagen hair syndrome is caused by mutations in the <i>WNT10A</i> gene and has a genetic overlap with male pattern hair loss British Journal of Dermatology · 2023
    4. Alopecia areata - Vitiligo overlap syndrome: An emerging clinical variant Indian Journal of Dermatology Venereology and Leprology · 2013 · 13 citations
    5. 306 Exploring the relationship between acne and mental health Journal of Investigative Dermatology · 2022
    6. Chronic overlapping pain conditions and nociplastic pain Human Genetics and Genomics Advances · 2024 · 16 citations
    7. Chronic Overlapping Pain Conditions and Nociplastic Pain medRxiv (Cold Spring Harbor Laboratory) · 2023
    8. A Homozygous Missense Variant in K25 Underlying Overlapping Phenotype with Woolly Hair and Dental Anomalies 2022 · 2 citations
    9. Overlapping features of atopic dermatitis and alopecia areata: from pathogenesis to treatment Frontiers in Immunology · 2025
    10. A new familial presentation of dissecting cellulitis: The genetic implications on scarring alopecias JAAD Case Reports · 2020 · 9 citations
    11. The Specific Dermatoses of Pregnancy Quality in Sport · 2025
    12. Primary scarring alopecias. A literature review 2024
    13. Genetic Basis of Alopecia Areata Dermatologic clinics · 2012 · 40 citations
    14. Association between androgenetic alopecia and cardiovascular diseases: a genetic correlation and Mendelian randomization study Archives of Dermatological Research · 2026
    15. Genetic and Environmental Factors Affecting Hair Density in East Asian Populations British Journal of Dermatology · 2025
    16. The Genetics of Seborrheic Dermatitis: A Candidate Gene Approach and Pilot Genome-Wide Association Study Journal of Investigative Dermatology · 2017 · 15 citations
    17. Hirsutism Beyond PCOS: Genome-wide Evidence for Genetic Factors Journal of Investigative Dermatology · 2026
    18. Genetics and Pathophysiology of Congenital Adrenal Hyperplasia Contemporary Endocrinology · 2017
    19. The genetics of autism and steroid-related traits in prenatal and postnatal life Frontiers in Endocrinology · 2023 · 1 citations
    20. The genetic basis of dermatophytosis skin infection susceptibility Nature Communications · 2026
    21. Genetics of Polycystic Ovary Syndrome 2016 · 1 citations
    22. An Autosomal Recessive Form of Monilethrix Is Caused by Mutations in DSG4: Clinical Overlap with Localized Autosomal Recessive Hypotrichosis Journal of Investigative Dermatology · 2006 · 97 citations
    23. Do Alopecia Areata and Hair Colour Have a Shared Genetic Component? Experimental Dermatology · 2026
    24. Gut instinct: Using tofacitinib to treat alopecia areata in the context of comorbid inflammatory bowel disease JAAD Case Reports · 2020 · 6 citations
    25. A Comprehensive Review of GWASs of Human Hair Traits Journal of Investigative Dermatology · 2025 · 1 citations
    26. A review of cutaneous lupus erythematosus: improving outcomes with a multidisciplinary approach Journal of Multidisciplinary Healthcare · 2019 · 26 citations
    27. 1381 Molecular mechanisms of donor dominance in androgenetic alopecia Journal of Investigative Dermatology · 2018
    28. MendelVar: gene prioritization at GWAS loci using phenotypic enrichment of Mendelian disease genes bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 2 citations
    29. A PAX1 enhancer locus is associated with susceptibility to idiopathic scoliosis in females Nature Communications · 2015 · 103 citations
    30. An update of the pathogenesis of frontal fibrosing alopecia: What does the current evidence tell us? Australasian Journal of Dermatology · 2018 · 23 citations