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    Glossary Genetic Loci for Patterned Hair Loss Susceptibility

    specific gene locations linked to increased risk of hair loss

    Genetic loci for patterned hair loss susceptibility refer to specific locations on genes that are associated with an increased risk of developing patterned hair loss, such as male or female pattern baldness. These loci contain variations in DNA that can influence how likely a person is to experience hair thinning or loss, often inherited from their parents. Understanding these genetic markers helps researchers and medical professionals identify individuals at higher risk and develop targeted treatments.

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    1. Investigation of the male pattern baldness major genetic susceptibility loci AR/EDA2R and 20p11 in female pattern hair loss British Journal of Dermatology · 2012 · 38 citations
    2. Evaluation of Susceptibility Genes/Loci Associated with Male Androgenetic Alopecia (MAGA) for Female-Pattern Hair Loss in a Chinese Han Population and a Brief Literature Review Medical Science Monitor · 2021 · 1 citations
    3. Genetics and other factors in the aetiology of female pattern hair loss Experimental Dermatology · 2017 · 43 citations
    4. Investigation of four novel male androgenetic alopecia susceptibility loci: no association with female pattern hair loss Archives of Dermatological Research · 2013 · 21 citations
    5. Six Novel Susceptibility Loci for Early-Onset Androgenetic Alopecia and Their Unexpected Association with Common Diseases PLOS Genetics · 2012 · 87 citations
    6. Molecular Genetics of Alopecias Current problems in dermatology · 2015 · 9 citations
    7. Six novel susceptibility Loci for early-onset androgenetic alopecia and their unexpected association with common diseases Faculty of Health; Institute of Health and Biomedical Innovation · 2012
    8. Mapping of cis-acting expression quantitative trait loci in human scalp hair follicles BMC Dermatology · 2020 · 4 citations
    9. Male-pattern baldness susceptibility locus at 20p11 Nature Genetics · 2008 · 111 citations
    10. Investigation of six novel susceptibility loci for male androgenetic alopecia in women with female pattern hair loss Journal of Dermatological Science · 2013 · 25 citations
    11. GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk Nature Communications · 2017 · 57 citations
    12. Moderne Untersuchungsmethoden zur Evaluation von Haarausfall und Alopezie bei Frauen Refubium (Universitätsbibliothek der Freien Universität Berlin) · 2018
    13. Male-pattern hair loss: Comprehensive identification of the associated genes as a basis for understanding pathophysiology Medizinische Genetik · 2023
    14. Genetic prediction of male pattern baldness PLoS Genetics · 2017 · 133 citations
    15. Dissection of genetic variation and evidence for pleiotropy in male pattern baldness Nature Communications · 2018 · 58 citations
    16. Genetic Differences between Male and Female Pattern Hair Loss in a Korean Population Life · 2024
    17. Use of genetics in the prediction of success in male pattern hair loss therapy and mechanistic studies Frontiers in Pharmacology · 2026
    18. Differences in male and female pattern hair loss based on androgens, estrogen, iron, vitamin D, lipid metabolism, and genetic regulation Journal of Cutaneous and Aesthetic Surgery · 2026
    19. Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness Nature communications · 2017 · 64 citations
    20. Genetic prediction of male pattern baldness based on large independent datasets European Journal of Human Genetics · 2022 · 3 citations
    21. Selected variants of the melanocortin 4 receptor gene (MC4R) do not confer susceptibility to female pattern hair loss Archives of Dermatological Research · 2012 · 9 citations
    22. Finding bald spots on chromosome 20p11 Clinical Genetics · 2009 · 1 citations
    23. Recent advances in the genetics of alopecia areata Medizinische Genetik · 2023
    24. The Genetic Landscape of Androgenetic Alopecia: Current Knowledge and Future Perspectives Biology · 2026
    25. Concomitant presentation of alopecia areata in siblings: A rare occurrence International Journal of Trichology · 2012 · 7 citations
    26. Male pattern hair loss: Can developmental origins explain the pattern? Experimental Dermatology · 2023
    27. Autophagy: Guardian of Skin Barrier Biomedicines · 2022 · 8 citations
    28. Alopecia Areata KARGER eBooks · 2008 · 24 citations
    29. Genome-Wide Association Study of Alopecia Areata in Taiwan: The Conflict Between Individuals and Hair Follicles Clinical, cosmetic and investigational dermatology · 2023 · 1 citations
    30. Female Pattern Hair Loss in Female and Male: A Quantitative Trichoscopic Analysis in Chinese Han Patients Frontiers in Medicine · 2021 · 1 citations