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    Glossary Genetic Loci for Patterned Hair Loss Susceptibility

    specific gene locations linked to increased risk of hair loss

    Genetic loci for patterned hair loss susceptibility refer to specific locations on genes that are associated with an increased risk of developing patterned hair loss, such as male or female pattern baldness. These loci contain variations in DNA that can influence how likely a person is to experience hair thinning or loss, often inherited from their parents. Understanding these genetic markers helps researchers and medical professionals identify individuals at higher risk and develop targeted treatments.

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    1. Investigation of the male pattern baldness major genetic susceptibility loci AR/EDA2R and 20p11 in female pattern hair loss British Journal of Dermatology · 2012 · 38 citations
    2. Evaluation of Susceptibility Genes/Loci Associated with Male Androgenetic Alopecia (MAGA) for Female-Pattern Hair Loss in a Chinese Han Population and a Brief Literature Review Medical Science Monitor · 2021 · 1 citations
    3. Genetics and other factors in the aetiology of female pattern hair loss Experimental Dermatology · 2017 · 43 citations
    4. Investigation of four novel male androgenetic alopecia susceptibility loci: no association with female pattern hair loss Archives of Dermatological Research · 2013 · 21 citations
    5. Six Novel Susceptibility Loci for Early-Onset Androgenetic Alopecia and Their Unexpected Association with Common Diseases PLOS Genetics · 2012 · 87 citations
    6. Molecular Genetics of Alopecias Current problems in dermatology · 2015 · 9 citations
    7. Six novel susceptibility Loci for early-onset androgenetic alopecia and their unexpected association with common diseases Faculty of Health; Institute of Health and Biomedical Innovation · 2012
    8. Mapping of cis-acting expression quantitative trait loci in human scalp hair follicles BMC Dermatology · 2020 · 4 citations
    9. Male-pattern baldness susceptibility locus at 20p11 Nature Genetics · 2008 · 111 citations
    10. GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk Nature Communications · 2017 · 57 citations
    11. Moderne Untersuchungsmethoden zur Evaluation von Haarausfall und Alopezie bei Frauen Refubium (Universitätsbibliothek der Freien Universität Berlin) · 2018
    12. Male-pattern hair loss: Comprehensive identification of the associated genes as a basis for understanding pathophysiology Medizinische Genetik · 2023
    13. Genetic prediction of male pattern baldness PLoS Genetics · 2017 · 133 citations
    14. Dissection of genetic variation and evidence for pleiotropy in male pattern baldness Nature Communications · 2018 · 58 citations
    15. Genetic Differences between Male and Female Pattern Hair Loss in a Korean Population Life · 2024
    16. Use of genetics in the prediction of success in male pattern hair loss therapy and mechanistic studies Frontiers in Pharmacology · 2026
    17. Differences in male and female pattern hair loss based on androgens, estrogen, iron, vitamin D, lipid metabolism, and genetic regulation Journal of Cutaneous and Aesthetic Surgery · 2026
    18. Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness Nature communications · 2017 · 64 citations
    19. Genetic prediction of male pattern baldness based on large independent datasets European Journal of Human Genetics · 2022 · 3 citations
    20. Recent advances in the genetics of alopecia areata Medizinische Genetik · 2023
    21. Selected variants of the melanocortin 4 receptor gene (MC4R) do not confer susceptibility to female pattern hair loss Archives of Dermatological Research · 2012 · 9 citations
    22. Finding bald spots on chromosome 20p11 Clinical Genetics · 2009 · 1 citations
    23. The Genetic Landscape of Androgenetic Alopecia: Current Knowledge and Future Perspectives Biology · 2026
    24. Faculty Opinions recommendation of Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2019
    25. Alopecia areata: What’s new in epidemiology, pathogenesis, diagnosis, and therapeutic options? Journal of dermatological science · 2016 · 56 citations
    26. Diagnosis and treatment of alopecia areata Journal of The Korean Medical Association · 2016
    27. Dermatological diseases from a genetic perspective Medizinische Genetik · 2023
    28. The genetics of autism and steroid-related traits in prenatal and postnatal life Frontiers in Endocrinology · 2023 · 1 citations
    29. Recent Advances in Understanding of the Etiopathogenesis, Diagnosis, and Management of Hair Loss Diseases Journal of Clinical Medicine · 2023
    30. Alopecia areata: a comprehensive review of clinical, immunologic, and genetic perspectives Discover Immunity. · 2025 · 2 citations