47 citations
,
May 2020 in “Cardiovascular Research” This review explores how sex differences influence the pathophysiology, incidence, and treatment outcomes of ischaemic heart disease, and emphasizes the need for more sex-specific research.
28 citations
,
June 2015 in “Journal of circadian rhythms” This study found that extreme morning and evening chronotypes exhibited significant differences in the timing of circadian clock gene expression in hair follicle cells.
4 citations
,
January 2023 in “Journal of Human Hypertension” This review discusses sex-related differences in antihypertensive treatment and reports original data showing better blood pressure control in women than men until their late sixties, when the trend reverses.
17 citations
,
December 2004 in “The Journal of Men's Health & Gender” This article discusses the role of androgens in hair follicle changes, explaining how dihydrotestosterone contributes to hair thinning on the scalp, while promoting thicker facial hair in men, and reports no new clinical results.
16 citations
,
February 2014 in “Iranian Red Crescent Medical Journal” This qualitative study revealed that women with PCOS often see themselves as less feminine, affected by symptoms like excess hair and irregular menstruation, which challenged their gender roles.
15 citations
,
April 2021 in “Annals of Translational Medicine” This review discusses facial gender confirmation surgery, particularly focusing on the upper third of the face, and reports no new clinical results; it emphasizes virtual surgical planning and postoperative care.
February 2025 in “Journal of Tissue Viability” This scoping review suggests that physiological differences in skin structure may affect how individuals with different skin tones respond to pressure ulcer development, emphasizing the need for targeted prevention strategies.
January 2025 in “HORMONES” This systematic review reported positive outcomes with gender-affirming hormone therapy in Canada and emphasized the urgent need for standardized outcome measurement tools to enhance evidence-based practices.
August 2023 in “Clinical, Cosmetic and Investigational Dermatology” In this study, the Hamilton-Norwood subtype of female pattern hair loss was associated with early onset and polycystic ovary syndrome, while the Ludwig pattern was more common overall.
February 2019 in “Obstetrics and gynaecology cases - reviews” This study compared hirsutism levels, hand measurements, testosterone, and DHEAS levels in women aged 18 to 38 but does not report new definitive findings.
110 citations
,
January 1984 in “Progress in brain research” This chapter reviews the potential role of gonadal hormones in sex differences in play and spatial behavior, noting a lack of conclusive evidence but suggesting perinatal androgen exposure might contribute to observed differences. It reports no new research results.
15 citations
,
September 2021 in “Frontiers in Endocrinology” This review discusses the impact of gender affirming hormone therapy on cardiovascular outcomes in transgender individuals and reports no new clinical results; the authors underscore the need for more comprehensive studies.
5 citations
,
September 2022 in “Facial Plastic Surgery & Aesthetic Medicine” This review discusses changes and advancements in facial feminization surgery, detailing various aspects of the field but reporting no new clinical results; the authors highlight ongoing innovations and challenges.
2 citations
,
February 2024 in “JAAD International” Sebaceous gland maturity and size differ between psoriatic alopecia and alopecia areata.
1 citations
,
September 2023 in “International Journal of Women’s Dermatology” This article discusses the teratogenic risks of skin condition treatments for individuals with DSD and notes that testosterone replacement, often used in this population, may cause acne.
January 2024 in “Medicina” This study assessed outcomes and complications of upper-face feminization surgery among 20 transgender patients, highlighting that insufficient browbone reduction was a common issue in prior surgeries, and emphasizing meticulous planning to prevent revisions and dissatisfaction.
2 citations
,
June 2024 in “Plastic Surgery” This cross-sectional study examined gender-affirming surgeries in Canada, finding significant variation in provincial insurance coverage, with Prince Edward Island covering the most procedures and Nunavut the least, while noting a general lack of in-province procedures in the territories.
4 citations
,
October 2018 in “Journal of Mind and Medical Sciences” This study found that Romanian men with schizophrenia had better mental functioning than women, and atypical antipsychotics were associated with improved quality of life across various dimensions for all patients.
April 2024 in “International journal of molecular sciences” This study examines the similarities and differences in the pathogenesis of autoimmune conditions alopecia areata and vitiligo, highlighting shared features like immune cell involvement and cytokine pathways, while noting differing immune responses in skin and hair.
3 citations
,
August 2021 in “Journal of the American Academy of Dermatology” This study reported that facial hair is a crucial aspect of gender identity and transition for transmen, with a majority dissatisfied with their current facial hair despite testosterone therapy.
13 citations
,
May 2019 in “Archives of dermatological research” In a study using hairless mice, tranexamic acid was found to ameliorate natural skin aging, with stronger effects observed in female mice compared to males.
This study suggests that keratin peptide signatures in human hair shafts may potentially be used to distinguish gender and ethnicity, although further validation with larger samples is needed.
This study suggests that keratin peptide signatures from human hair shafts could potentially distinguish gender and ethnicity, though confirmation in larger studies is needed.
6 citations
,
July 2024 in “Journal of Cosmetic Dermatology” In this study, researchers found that a composition containing mannose-6-phosphate significantly reduced the total skin pore area by 24% in women after 56 days and by 30.2% in men after 7 days, suggesting its effectiveness in improving pore appearance by targeting dermal and epidermal modifications.
February 2025 in “Animals” This study involving 81 yaks found significant correlations between melatonin, dihydrotestosterone, and immunoglobulin levels in blood serum and mineral content in hair, suggesting these factors may jointly influence yak hair growth and immune status, providing a potential non-invasive indicator of overall health.
July 2024 in “Anais Brasileiros de Dermatologia” This study describes the creation and two-year experience of a pioneering dermatological practice exclusively serving transgender and non-binary patients to address their unique dermatological concerns and promote healthcare equity, based on a retrospective analysis of 114 patients at a public hospital.
19 citations
,
November 2021 in “Reviews in endocrine and metabolic disorders” This article discusses the role of sex hormones in COVID-19 fatality differences between sexes and reports no new clinical results, suggesting that future strategies should consider sex-specific approaches.
9 citations
,
April 2021 in “Annals of Translational Medicine” This study observed that facial feminization surgery significantly improved facial appearance and alleviated gender dysphoria among Chinese transgender females, with all patients expressing satisfaction post-surgery.
February 2026 in “British Journal of Sports Medicine” Transgender women have similar fitness to cisgender women, while transgender men have higher fat and lower strength than cisgender men; hormone therapy affects body composition and strength.
40 citations
,
July 2016 in “Pediatrics in review” This article reviews puberty's onset, development, and the factors affecting it, including nutrition, obesity, and gender dysphoria, and reports no new clinical results.