April 2022 in “International journal of respiratory and pulmonary medicine” The authors propose that higher testosterone levels in hospitalized COVID-19 patients might be associated with worse outcomes.
56 citations
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October 1983 in “Archives of Dermatology” This study found that free testosterone levels were a more sensitive indicator of hyperandrogenism in women with acne than total testosterone levels.
May 2013 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that women with hair loss had significantly higher free testosterone levels compared to those without hair loss.
March 2024 in “BMC women's health” This study found that free testosterone levels were 29% higher with the levonorgestrel implant than with the DMPA injection, which may impact sexual function, mood, and side effects like acne.
4 citations
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August 2019 This study found that elevated free testosterone levels may reduce body fat and increase bone density in males, but also raise the risk of prostate cancer, hair loss, and benign prostate hyperplasia.
2 citations
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December 2024 in “Iraqi Journal of Laser” This study used enhanced Raman spectroscopy to successfully detect ultra-low levels of free testosterone in women with PCOS, suggesting a potential low-cost method for early diagnosis.
43 citations
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January 2007 in “Gynecological Endocrinology” This study found that 9 out of 12 women with acne or alopecia showed subjective improvement with finasteride treatment despite having normal free testosterone levels, suggesting a potential role of 5alpha-reductase activity.
July 2021 in “International Journal of Community Medicine and Public Health” This study found that testosterone levels are commonly low among men with type 2 diabetes, and most of these men exhibit symptoms of hypogonadism, with BMI being a significant risk factor.
In this study, researchers developed a chemiluminescence assay kit for detecting free testosterone, showing it performed well and met clinical demands with low cost and automation; free testosterone levels differed in patients with various diagnoses, suggesting its diagnostic relevance for diseases such as prostate malignancy.
January 2009 in “Academic Journal of Second Military Medical University” In this study, adolescent male acne patients with normal serum testosterone showed improved outcomes with finasteride plus lifestyle intervention, significantly reducing DHT and free testosterone levels and improving SHBG levels, with minimal adverse effects.
July 2012 in “The Journal of Urology” This abstract reviews testosterone supplementation with and without a dual 5α-reductase inhibitor on fat-free mass in men with suppressed testosterone production and reports no new research findings.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this cross-sectional study at a tertiary care hospital, researchers found a significant correlation between cutaneous manifestations like hirsutism and acne and biochemical hyperandrogenism levels in women with PCOS, suggesting these skin conditions can predict elevated androgen levels.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that hirsutism and acne are strong predictors of biochemical hyperandrogenism in women with polycystic ovary syndrome.
1 citations
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January 2023 in “Journal of Obstetrics and Gynaecology” This study found that pregnant Egyptian women with PCOS and recurrent miscarriages showed elevated DHEA levels and shortened cervical length, which may negatively impact pregnancy outcomes.
64 citations
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August 1999 in “The American journal of medicine” This study found that while a transscrotal testosterone patch increases serum testosterone levels in hypogonadal men with AIDS and weight loss, it does not improve weight, body cell mass, or quality of life.
January 2016 in “Journal of SAFOG” This study observed that androgenic hormone levels were higher in high school girls with PCOS phenotypes accompanied by menstrual disorders, particularly oligomenorrhea.
18 citations
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January 1985 in “Acta Obstetricia Et Gynecologica Scandinavica” In this study of hirsute women, researchers found that correlations between hirsutism and hyperandrogenism were observed only in patients with a low LH/FSH ratio.
166 citations
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March 2007 in “Hypertension” In this study, hyperandrogenemia in young women with polycystic ovary syndrome was linked to higher blood pressure, independent of factors like age, insulin resistance, obesity, or dyslipidemia.
18 citations
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May 1992 in “American Journal of Biological Anthropology” This study found no general elevation in androgen levels among men predisposed to balding, despite a correlation with the free-to-total testosterone ratio; no link was observed with acne.
17 citations
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February 2019 in “Journal of Clinical Medicine” This article reviews guidelines for testosterone replacement therapy in late-onset hypogonadism, emphasizing the need for clear indications and appropriate testing before treatment, but provides no new research findings.
January 2018 in “Journal of translational science” In this study, oral broccoli sprouts intake did not affect plasma androgen levels in males, while alfalfa sprouts intake increased testosterone and DHT levels, which may help prevent male late onset hypogonadism.
32 citations
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January 1990 in “Clinical Endocrinology” This study found that women with female pattern androgenic alopecia have significantly higher levels of certain androgens and androgen sulfates compared to normal premenopausal women, suggesting markers for diagnosis and treatment efficacy.
16 citations
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December 2010 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” This study determined that the upper normal cut-off levels for free testosterone, dehydroepiandrosterone sulfate, and total testosterone among reproductive-age women in China are 26 pmol/L, 4.92 μmol/L, and 2.39 nmol/L, respectively.
2 citations
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July 2019 in “Pakistan Journal of Biological Sciences” This study suggests that perforin/granzyme-B might play a role in the interaction of sex hormones in patients with polycystic ovary syndrome.
January 1986 in “Journal of Steroid Biochemistry” Women with severe acne, hirsutism, and androgenic alopecia often have higher levels of certain androgens, but the specific pattern can't be predicted just by looking at symptoms.
7 citations
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January 2016 in “Experimental and Clinical Endocrinology & Diabetes” This study observed that adding simvastatin to ongoing metformin treatment reduced certain androgen levels in women with non-classic congenital adrenal hyperplasia and abnormal glucose metabolism, suggesting a potential therapeutic benefit.
9 citations
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October 2018 in “Medical Science Monitor” In this study, oral finasteride therapy was associated with decreased DHT levels and improved hair loss severity in young male AGA patients, while hormonal changes influenced the curative effect.
16 citations
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January 2000 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study found that serum PSA levels are higher in hirsute women and can be significantly reduced by antiandrogen treatment, suggesting PSA as a marker of androgen action in females.
2 citations
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January 2014 in “International Journal of Endocrinology” In this study, women with a complete hydatidiform mole had significantly higher pre-evacuation levels of hCG, free testosterone, and DHEA-S compared to controls, which declined after HM evacuation.
May 2013 in “Journal of the Egyptian Women's Dermatologic Society (Print)” In this study, elevated serum levels of aldosterone and free testosterone, along with increased androgen and aldosterone receptor levels, were associated with early-onset androgenetic alopecia in female patients.