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    Glossary Fractional Lasers

    target small skin areas to boost collagen and rejuvenation

    Fractional lasers, also known as fractional laser therapy or fractional laser resurfacing, are a type of laser treatment that targets small, precise areas of the skin to promote collagen production and skin rejuvenation. By creating microscopic columns of treated skin surrounded by untreated tissue, these lasers help in faster healing and are commonly used for reducing wrinkles, scars, and pigmentation issues.

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    1. Enhancing hair growth in male androgenetic alopecia by a combination of fractional CO2 laser therapy and hair growth factors Lasers in Medical Science · 2017 · 26 citations
    2. Comparative study of the use of fractional CO 2 laser versus the use of liquid nitrogen cryotherapy in the treatment of alopecia areata in a sample of the Egyptian population Dermatologic Therapy · 2022 · 8 citations
    3. Laser-Assisted Exosome Delivery (LAED) with Fractional CO2 Laser: A Pilot Two-Case Report and Narrative Review Cosmetics · 2025 · 6 citations
    4. Study on different fractional CO2 laser parameters combined with halometasone in treatment of chronic eczema Lasers in Medical Science · 2025 · 2 citations
    5. A comparative study of Fractional co2 laser combined with topical methotrexate versus Fractional co2 laser combined with topical [Calcipotriol + Betamethasone] in the treatment of nail psoriasis QJM · 2021 · 2 citations
    6. A comparative study of fractional CO2 laser with topical triamcinolone acetonide versus intralesional triamcinolone acetonide in the treatment of alopecia areata Journal of Cutaneous and Aesthetic Surgery · 2024 · 1 citations
    7. Fractional CO₂ laser combined with topical compound betamethasone for Vitiligo-Associated Leukotrichia: a retrospective study of 13 patients with limited effectiveness 2026
    8. Fractional CO2 laser vs Intralesional Corticosteroids in Alopecia Areata: A comparative study of Efficacy, Safety and Predictive factors Eurasian Journal of Scientific and Multidisciplinary Research · 2025
    9. Comparative study between fractional CO2 laser alone versus fractional CO2 laser combined with topical dutasteride in treatment of male androgenic alopecia Lasers in Medical Science · 2025
    10. Treatment of Alopecia Areata using Transdermal Delivery of 5-Fluorouracil by Fractional CO2 Laser versus Intralesional Injection of 5-Fluorouracil Zagazig University Medical Journal · 2024
    11. Fractional CO2 laser, platelet rich plasma and combination of both in treatment of female pattern hair loss 2024
    12. Fractional CO2 laser versus Microneedling followed by Topical 5 Fluorouracil in the treatment of Non-Segmental Vitiligo 2024
    13. Fractional CO2 laser versus Microneedling followed by Topical 5 Fluorouracil in the treatment of Non-Segmental Vitiligo 2024
    14. Efficacy and Safety of Fractional CO2 Laser Combined with Halometasone Cream for Treatment of Moderate-to-Severe Chronic Hand Eczema: A Prospective, Single-Center, Parallel-Group, Open-Label Randomized Trial Dermatology and Therapy · 2023
    15. Efficacy of fractional CO2 laser in combination with stromal vascular fraction (SVF) compared with fractional CO2 laser alone in the treatment of burn scars: a randomized controlled clinical trial Research Square (Research Square) · 2023
    16. A Comparative Study on Adipose-Derived Mesenchymal Stem Cells Secretome Delivery Using Microneedling and Fractional CO2 Laser for Facial Skin Rejuvenation [Response to Letter] Clinical Cosmetic and Investigational Dermatology · 2023
    17. Comparative Study of The Effect of Topical Minoxidil 5% Versus Combined Fractional CO2 Laser and Topical Minoxidil 5% in Treatment of Male Androgenetic Alopecia The Egyptian Journal of Hospital Medicine · 2022
    18. Effects of CO2 fractional laser on hair growth in C57BL/6 mice and potential underlying mechanisms Chinese Medical Journal · 2019 · 3 citations
    19. Novel approach with fractional ultrapulse CO2 laser for the treatment of upper eyelid dermatochalasis and periorbital rejuvenation Lasers in medical science · 2013 · 24 citations
    20. Alopecia areata treated using CO2 fractional laser with different parameters Lasers in Medical Science · 2025
    21. Enhancing hair regrowth in Alopecia areata: the power duo of CO2 fractional laser and Bimatoprost Archives of Dermatological Research · 2025
    22. Therapeutic Efficacy of Bovine Basic Fibroblast Growth Factor Combined with Ultrapulsed Fractional CO2 Laser in Acne Scars: Randomized Controlled Trial Clinical Cosmetic and Investigational Dermatology · 2023 · 6 citations
    23. A systematic review and meta-analysis on the effects of the ultra-pulse CO2 fractional laser in the treatment of depressed acne scars Annals of Palliative Medicine · 2022 · 26 citations
    24. Current Status of Fractional Laser Resurfacing JAMA Facial Plastic Surgery · 2015 · 44 citations
    25. Skin Permeation of Small-Molecule Drugs, Macromolecules, and Nanoparticles Mediated by a Fractional Carbon Dioxide Laser: The Role of Hair Follicles Pharmaceutical research · 2012 · 43 citations
    26. The Effect of the Fractional Carbon Dioxide Laser on Improving Minoxidil Delivery for the Treatment of Androgenetic Alopecia Journal of lasers in medical sciences · 2019 · 6 citations
    27. Platelet‐rich plasma injection versus combined fractional carbon dioxide laser with platelet‐rich plasma in treatment of vitiligo: A comparative study Journal of Cosmetic Dermatology · 2023 · 3 citations
    28. A study to assess the efficacy of fractional carbon dioxide laser with topical platelet-rich plasma in the treatment of androgenetic alopecia Lasers in Medical Science · 2022 · 2 citations
    29. Successful Response to a Combination of Intralesional Methotrexate and Fractional CO<sub>2</sub> Laser in Refractory Alopecia Areata: Case Report Skin appendage disorders · 2022 · 2 citations
    30. Comparative Study Between Ablative Fractional Carbon Dioxide Laser Combined with Topical Steroid Versus Topical Steroid in Treatment of Alopecia Areata Iraqi postgraduate medical journal · 2025