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    Glossary Fractional Lasers

    target small skin areas to boost collagen and rejuvenation

    Fractional lasers, also known as fractional laser therapy or fractional laser resurfacing, are a type of laser treatment that targets small, precise areas of the skin to promote collagen production and skin rejuvenation. By creating microscopic columns of treated skin surrounded by untreated tissue, these lasers help in faster healing and are commonly used for reducing wrinkles, scars, and pigmentation issues.

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    1. Synergistic Effects of Fractional CO <sub>2</sub> Laser and Recombinant Humanized Type III Collagen (rhCol III) in Atrophic Acne Scar Treatment: Activation of MAPK Pathway and Enhanced Collagen Remodeling Dermatologic Therapy · 2025
    2. Comparative study of the use of fractional CO 2 laser versus the use of liquid nitrogen cryotherapy in the treatment of alopecia areata in a sample of the Egyptian population Dermatologic Therapy · 2022 · 8 citations
    3. The Efficacy and Safety of Ablative Fractional CO <sub>2</sub> Laser Combined With Topical Minoxidil for Male Androgenetic Alopecia: A Randomized Clinical Trial Dermatologic Therapy · 2026
    4. Efficacy and Safety of Ablative Fractional CO <sub>2</sub> Laser Therapy for Localized Scleroderma: A Comprehensive Bench‐to‐Bedside Approach Dermatologic Therapy · 2025
    5. Lipid-based nanocarriers coupled with CO 2 laser-mediated drug delivery enhance skin penetration and hair follicle targeting Journal of drug targeting · 2026
    6. Eyelid skin tightening: a novel ‘Niche’ for fractional CO<sub>2</sub> rejuvenation 2011 · 27 citations
    7. Faculty Opinions recommendation of Treatment of alopecia areata with nonablative fractional laser combined with topical minoxidil. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2020
    8. Expression of collagen type I, skin fibroblasts and macrophages after 1550 nm erbium glass fractional laser in androgenic alopecia 2020
    9. Current Status of Fractional Laser Resurfacing JAMA Facial Plastic Surgery · 2015 · 44 citations
    10. Histologic comparison of microscopic treatment zones induced by fractional lasers and radiofrequency Journal of Cosmetic and Laser Therapy · 2014 · 27 citations
    11. Study on different fractional CO2 laser parameters combined with halometasone in treatment of chronic eczema Lasers in Medical Science · 2025 · 2 citations
    12. Fractional Laser-assisted Hair Regrowth and Microneedling for the Treatment of Alopecia Areata: A Review Cureus · 2019 · 7 citations
    13. Fractional non-ablative laser-assisted drug delivery leads to improvement in male and female pattern hair loss Journal of Cosmetic and Laser Therapy · 2018 · 15 citations
    14. The role of fractional laser‐assisted drug delivery in enhancing the efficacy of topical bimatoprost solution in the treatment of alopecia areata: An intra‐patient comparative randomized clinical trial Journal of Cosmetic Dermatology · 2024
    15. Hair Loss Treatment Using Erbium:YAG Fractional Laser with Hair Growth-promoting Solution Medical lasers · 2021
    16. Combination of a non-ablative 1,927 nm thulium fiber fractional laser and autologous platelet-rich plasma in treatment of male androgenetic alopecia: A pilot study Chulalongkorn Medical Journal · 2019
    17. Efficacy and Safety of Fractional CO2 Laser Combined with Halometasone Cream for Treatment of Moderate-to-Severe Chronic Hand Eczema: A Prospective, Single-Center, Parallel-Group, Open-Label Randomized Trial Dermatology and Therapy · 2023
    18. Fractional CO2 laser, platelet rich plasma and combination of both in treatment of female pattern hair loss 2024
    19. Lasers in dermatology Medical laser application · 2008 · 3 citations
    20. Skin Permeation of Small-Molecule Drugs, Macromolecules, and Nanoparticles Mediated by a Fractional Carbon Dioxide Laser: The Role of Hair Follicles Pharmaceutical research · 2012 · 43 citations
    21. The Effect of Conditioned Media From Human Adipocyte-Derived Mesenchymal Stem Cells on Androgenetic Alopecia After Nonablative Fractional Laser Treatment Dermatologic Surgery · 2020 · 10 citations
    22. Effects of CO2 fractional laser on hair growth in C57BL/6 mice and potential underlying mechanisms Chinese Medical Journal · 2019 · 3 citations
    23. Follicular unit extraction combined with fractional carbon dioxide laser therapy for post‐traumatic eyebrow scar with defects: A prospective and comparative study Journal of Cosmetic Dermatology · 2024 · 3 citations
    24. Fractional carbon dioxide laser alone and as an assisted drug delivery for treatment of alopecia areata: a clinical, dermoscopic and immunohistochemical study Archives of Dermatological Research · 2023
    25. Effects of non-ablative fractional erbium glass laser treatment on gene regulation in human three-dimensional skin models Lasers in Medical Science · 2016 · 24 citations
    26. Therapeutic Efficacy of Bovine Basic Fibroblast Growth Factor Combined with Ultrapulsed Fractional CO2 Laser in Acne Scars: Randomized Controlled Trial Clinical Cosmetic and Investigational Dermatology · 2023 · 6 citations
    27. Fetal Fibroblast Transplantation via Ablative Fractional Laser Irradiation Reduces Scarring Biomedicines · 2023 · 2 citations
    28. American Society for Laser Medicine and Surgery 2019 Late Breaking Abstracts Lasers in Surgery and Medicine · 2019 · 1 citations
    29. A Novel Treatment of Acne Vulgaris Using a 1927 nm Fractional Thulium Laser: A Case Series Clinical Cosmetic and Investigational Dermatology · 2024 · 3 citations
    30. Laser therapies in androgenetic alopecia: Review and clinical experiences Journal of Cutaneous and Aesthetic Surgery · 2025