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A protein called sFRP4 from skin cells stops the development of pigment-producing cells in hair.

Hair follicle cells age faster and lose pigment due to less catalase, causing hair to turn gray.

Hair grays due to oxidative stress and fewer functioning melanocytes.

Only skin melanocytes, not other types, can color hair in mice.

Overexpression of HDGF in melanocytes does not cause cancer.

Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.

Beige and leaden pigment genes act within melanocytes, affecting pigment patterns.

Fetal hair follicles have melanocytes with melanosomes at different stages, which are broken down into pigment particles in keratinocytes.

Human skin's melanocytes respond to light by changing shape, producing pigments and hormones, which may affect sleep patterns.

Surgical methods like suction blister grafting and split-thickness skin grafting are highly successful for vitiligo repigmentation, but choosing the right patients is crucial for success.

A substance called TCQA could potentially darken hair by activating certain genes and increasing melanin.

Palmitoyl tetrapeptide-20 may help reduce hair greying and increase melanin production.

Segmental Vitiligo is a stable, early-onset form of vitiligo that responds well to early treatment and is ideal for repigmentation studies.

Hair color is influenced by genetics and can indicate certain health conditions.

Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.

Other common signs, not just the well-known immune cells around hair bulbs, are important for diagnosing hair loss from alopecia areata.

Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.

Scalp cooling is the most effective FDA-approved method to prevent chemotherapy-induced hair loss, but more research is needed for other treatments.

The document explains hair biology, the causes of hair loss, and reviews various hair loss treatments.

Chemotherapy caused hair loss with specific patterns, but most patients had hair regrowth after treatment, while some had lasting hair loss.

Pigmented casts are common in several hair loss conditions and can help diagnose specific types of alopecia.

Hair color is determined by different melanins and changes with age.

Hair growth is influenced by hormones and goes through different phases; androgens can both promote and inhibit hair growth depending on the body area.

T-cell reconstitution after thymus transplantation can cause hair whitening and loss.

Researchers found new hair and nail genes, how hair reacts to UV, differences in white and pigmented hair growth, nerve changes in alopecia, treatments for baldness and alopecia, a toenail condition linked to a genetic disorder, and that nail fungus is more common in people with psoriasis.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.

Androgens can both increase and decrease hair growth in different parts of the body.

Hair color loss can indicate the effectiveness of a drug targeting the KIT protein in mice and humans.

Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.