17 citations
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September 2022 in “Genes & Genomics” In this study, researchers identified specific long non-coding RNAs involved in feather development that do not follow traditional genetic inheritance patterns in chickens.
August 2024 in “Skin Appendage Disorders” This study introduces "alopecia areata in a male or female pattern distribution" as a new clinical subtype of alopecia areata, observed in three adult cases, to enhance diagnostic precision and treatment personalization.
February 2023 in “Journal of dermatology” This letter reports the first known Japanese case of autosomal recessive woolly hair/hypotrichosis with compound heterozygous mutations in the LIPH gene.
10 citations
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January 2010 in “Veterinary pathology” This study found that a newly identified mutation in the hairless gene in mice led to decreased Hr mRNA levels and changes in gene expression related to hair follicle development.
11 citations
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January 2005 in “Brazilian Journal of Medical and Biological Research” This study found no qualitative skin differences during development between mutant hairless USP mice and BALB/c mice, except for enlarged cysts in the hairless strain.
3 citations
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March 2014 in “Veterinary dermatology” This study reports the first documentation of mural, mucinotic, isthmus folliculitis alopecia in Norwegian puffin dogs, noting that ciclosporin treatment led to remission while other treatments were less effective.
21 citations
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June 2009 in “Mammalian genome” This study describes a mouse model for Marie Unna Hereditary Hypotrichosis, identifying mutations in the hairless gene that result in sparse or absent hair and cyst-like hair follicles.
March 2026 in “JID Innovations” In a mouse model study, researchers found that mutations in Aire reduced alopecia areata frequency, while Notch4 mutations did not lead to the disease, likely due to proximity with a resistance gene.
103 citations
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March 2011 in “PLoS Biology” This study found that a mutation in the BMP12/GDF7 gene is associated with the Naked neck trait in chickens, reducing neck feathering due to altered signaling pathways.
36 citations
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January 2000 in “British journal of dermatology/British journal of dermatology, Supplement” This case study reports on a mother and daughter with ichthyosis follicularis, alopecia, and photophobia, noting consistent keratotic eruptions during the mother's pregnancies that improved postpartum.
21 citations
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March 2018 in “American Journal Of Pathology” In this study, it was observed that NIPAL4 mutations linked to autosomal recessive congenital ichthyosis lead to abnormal skin barrier function due to cytotoxic effects disrupting lipid structure and organization, which topical treatments only partially ameliorated.
September 2025 in “Digital Commons - RU (Rockefeller University)” In this study, researchers found that mice lacking the transcription factor FOXC1 in their hair follicle stem cells had increased rounds of hair regeneration but experienced hair thinning due to impaired ability to maintain stem cell quiescence and adhesion.
1 citations
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November 2010 in “Pediatric dermatology” This article provides no abstract and reports on a case of an 11-month-old girl lacking scalp and body hair without offering new clinical findings.
14 citations
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March 2000 in “Journal of Zoo and Wildlife Medicine” This study identified a new Demodex species causing demodicosis in a zoo koala, successfully treated with daily oral ivermectin.
1 citations
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February 2022 in “Online journal of biological sciences” This article reviews the congenital disorder aphallia, describing its rarity, clinical characteristics, and the normal hormonal and chromosomal profiles of affected individuals, but does not report new research findings.
February 2021 in “PubMed” This case report presents a 2-year-old girl with type B loose anagen syndrome diagnosed through a painless hair pull test, avoiding unnecessary further tests or referrals.
1 citations
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January 2022 in “Annals of Dermatology” In this case report, researchers identified a novel homozygous missense mutation in the MBTPS2 gene associated with the mild form of IFAP syndrome in a 7-year-old boy.
1 citations
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February 2024 in “Australasian Journal of Dermatology” In this case study, a tick bite from the genus Ixodes in a 9-year-old girl was associated with the development of localized alopecia areata, resembling telogen effluvium, which resolved completely in less than three months.
158 citations
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December 2002 in “Development” In this study, Msx2-deficient mice showed progressive hair loss due to shortened anagen phase and prolonged catagen and telogen phases, resulting in cyclic alopecia with structurally abnormal hair shafts.
25 citations
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April 1941 in “Experimental biology and medicine” This study found that mice developed alopecia when deficient in pantothenic acid, even when inositol was present.
This study discovered that in *Drosophila*, knockdown of specific storage proteins in adipocytes decreased germline stem cell maintenance, implicating a role for these proteins in adult tissue regulation.
7 citations
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April 2000 in “Mammalian Genome” This study identified a new mutation in SELH/Bc mice causing distinctive whisker and body hair abnormalities, mapped near the type I keratin cluster on chromosome 11.
2 citations
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May 2022 in “Stem cell research & therapy” This study found that hair follicle stem cells in the hairpoor mouse, a model for Marie-Unna hypotrichosis, lose their quiescent state, leading to a disordered hair cycle and contributing to alopecia.
November 2009 in “Hair transplant forum international” This piece presents no new research findings; it briefly mentions opinions on Female Pattern Hair Loss and the importance of increasing awareness.
32 citations
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January 2017 in “Orphanet journal of rare diseases” This article reviews the genetic basis, diagnostic approaches, and treatment options for nude severe combined immunodeficiency, but does not present any new research findings.
93 citations
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May 1990 in “The EMBO Journal” Mice with extra sheep genes had hair that fell out and regrew in cycles.
April 2018 in “Journal of Investigative Dermatology” Mutations in Far2 mice cause hair loss due to sebaceous gland issues.
April 2026 in “Human Genome Variation” This study identified a specific hemizygous intronic variant in the MBTPS2 gene associated with IFAP syndrome in a patient, revealing exon skipping and reduced normal transcript expression through long-read RNA sequencing.
January 2025 in “Indian Journal of Unani Medicine” This case study observed that a Unani medicine regimen significantly improved hair shedding and quality of life in a 24-year-old female with Telogen Effluvium following a febrile illness, showing potential effectiveness and safety in this context.
3 citations
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August 2004 in “Veterinary Dermatology” This study observed that supplementing with vitamins, iodine, cobalt, and selenium prevented hair follicle growth arrest in Icelandic horses during winter.