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    Glossary FGF signaling pathway

    proteins bind to cell receptors, regulating growth and development

    The FGF signaling pathway, also known as the Fibroblast Growth Factor signaling pathway, is a crucial biological system that involves a group of proteins called fibroblast growth factors (FGFs). These proteins bind to specific receptors on the surface of cells, triggering a cascade of events inside the cell that regulate various processes such as cell growth, development, wound healing, and tissue repair. This pathway is essential for normal development and maintenance of tissues, and its dysregulation can lead to diseases like cancer and developmental disorders.

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    1. Cooperation of TGF‐β and FGF signalling pathways in skin development Cell Proliferation · 2023 · 23 citations
    2. Disruption of the hedgehog signaling pathway contributes to the hair follicle cycling deficiency in Vdr knockout mice Journal of Cellular Physiology · 2010 · 53 citations
    3. Recombinant Type XVII Collagen Promotes Hair Growth by Activating the Wnt/β-Catenin and SHH/GLI Signaling Pathways Cosmetics · 2025
    4. Androgenetic alopecia: combing the hair follicle signaling pathways for new therapeutic targets and more effective treatment options Expert Opinion on Therapeutic Targets · 2019 · 19 citations
    5. Careless talk costs lives: fibroblast growth factor receptor signalling and the consequences of pathway malfunction Trends in Cell Biology · 2014 · 119 citations
    6. Defining ovine dermal papilla cell markers and identifying key signaling pathways regulating its intrinsic properties Frontiers in Veterinary Science · 2023 · 5 citations
    7. Nitrate Promoting Hair Growth Through Enhancing Wnt/β-catenin and Downregulating TGF-β/Samd/BMP signaling pathway in C57BL/6 Mice bioRxiv (Cold Spring Harbor Laboratory) · 2024
    8. Myc and Fgf Are Required for Zebrafish Neuromast Hair Cell Regeneration PloS one · 2016 · 21 citations
    9. Feather arrays are patterned by interacting signalling and cell density waves PLoS Biology · 2019 · 133 citations
    10. Single-cell transcriptomics reveals the natural product Shi-Bi-Man promotes hair regeneration by activating the FGF pathway in dermal papilla cells Phytomedicine · 2022 · 2 citations
    11. Micro‐RNA‐31 controls hair cycle‐associated changes in gene expression programs of the skin and hair follicle ˜The œFASEB journal · 2010 · 149 citations
    12. Transcriptome Reveals Long Non-coding RNAs and mRNAs Involved in Primary Wool Follicle Induction in Carpet Sheep Fetal Skin Frontiers in physiology · 2018 · 37 citations
    13. Regeneration of hair and other skin appendages: A microenvironment‐centric view Wound Repair and Regeneration · 2016 · 10 citations
    14. Effects of photobiomodulation at various irradiances on normal and dihydrotestosterone‐treated human hair dermal papilla cells in vitro Journal of Biophotonics · 2023 · 1 citations
    15. Molecular Mechanisms Affecting Development of Animal Fibers and Some Studies on Goats Livestock studies · 2023
    16. The Historical Studies Underpinning the Concept of Hair Follicle Neogenesis Springer eBooks · 2022
    17. The stem cell niche The Journal of Pathology · 2008 · 209 citations
    18. Identifying the Target Cells and Mechanisms of Merkel Cell Polyomavirus Infection Cell Host & Microbe · 2016 · 133 citations
    19. Hair follicle stem cells and intrafollicular homeostasis TURKDERM · 2014 · 1 citations
    20. Data Sheet 2_Quercetin promotes production of secondary hair follicle stem cells in cashmere goat: a mechanistic study.zip OPAL (Open@LaTrobe) (La Trobe University) · 2025
    21. Research Highlights: γδ T cells regulate hair follicle neogenesis during adult wound healing Regenerative Medicine · 2013
    22. TNF superfamily in skin appendage development Cytokine & growth factor reviews · 2008 · 86 citations
    23. An Integrated Transcriptome Atlas of Embryonic Hair Follicle Progenitors, Their Niche, and the Developing Skin Developmental cell · 2015 · 173 citations
    24. [Regulation of hair follicle cycle]. PubMed · 2014 · 4 citations
    25. Exosome-based Therapies for Androgenetic Alopecia: Mechanisms, MicroRNAs, and Clinical Prospects Gene Expression · 2025
    26. The potential of Spirulina maxima extract-treated conditioned medium from adipose-derived mesenchymal stem cells for hair growth promoting effect on human dermal papilla cells Regenerative Therapy · 2025
    27. Evaluation of Efficacy of Water-Soluble Fraction of Rhus semialata Gall Extract and Penta-O-Galloyl-β-D-Glucose on Mitigation of Hair Loss: An In Vitro and Randomized Double-Blind Placebo-Controlled Clinical Study Antioxidants · 2025
    28. Adenosine Stimulates Fibroblast Growth Factor-7 Gene Expression Via Adenosine A2b Receptor Signaling in Dermal Papilla Cells 2007 · 66 citations
    29. Sprouty/FGF signaling regulates the proximal–distal feather morphology and the size of dermal papillae Developmental Biology · 2012 · 50 citations
    30. Signaling pathways involved in hair follicle cycling and morphogenesis International Journal of Dermatology and Venereology · 2012