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    Glossary Extracellular Matrix

    complex network of proteins and molecules supporting cell structure

    The Extracellular Matrix (ECM) is a complex network of proteins and other molecules that surround and support cells within tissues and organs. It provides structural support, influences cell behavior, and plays a crucial role in processes like wound healing and tissue regeneration.

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    1. Differences in Hair Follicle Dermal Papilla Volume are Due to Extracellular Matrix Volume and Cell Number: Implications for the Control of Hair Follicle Size and Androgen Responses Journal of Investigative Dermatology · 1999 · 231 citations
    2. Extracellular matrix sensing by FERONIA and Leucine‐Rich Repeat Extensins controls vacuolar expansion during cellular elongation in <i>Arabidopsis thaliana</i> The EMBO Journal · 2019 · 172 citations
    3. Extracellular Matrix Degradation Products and Low-Oxygen Conditions Enhance the Regenerative Potential of Perivascular Stem Cells Tissue Engineering Part A · 2010 · 91 citations
    4. Epithelial Growth by Rat Vibrissae Follicles In Vitro Requires Mesenchymal Contact via Native Extracellular Matrix Journal of Investigative Dermatology · 1990 · 66 citations
    5. Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate International Journal of Molecular Sciences · 2018 · 57 citations
    6. Subpopulations of dermal skin fibroblasts secrete distinct extracellular matrix: implications for using skin substitutes in the clinic British Journal of Dermatology · 2017 · 50 citations
    7. Distribution of Extracellular Matrix Molecules in Human Hair Follicles Annals of the New York Academy of Sciences · 1991 · 45 citations
    8. The enhancement of dermal papilla cell aggregation by extracellular matrix proteins through effects on cell–substratum adhesivity and cell motility Biomaterials · 2009 · 44 citations
    9. Minoxidil improves vascular compliance, restores cerebral blood flow, and alters extracellular matrix gene expression in a model of chronic vascular stiffness American Journal of Physiology-heart and Circulatory Physiology · 2018 · 34 citations
    10. Use of extracellular matrix hydrogel from human placenta to restore hair-inductive potential of dermal papilla cells Regenerative Medicine · 2019 · 31 citations
    11. Leucocyte-Rich Platelet-Rich Plasma Enhances Fibroblast and Extracellular Matrix Activity: Implications in Wound Healing International Journal of Molecular Sciences · 2020 · 28 citations
    12. Cultured dermal papilla cells of the rat vibrissa follicle. Proliferative activity, adhesion properties and reorganization of the extracellular matrix in vitro Archives of Dermatological Research · 1997 · 27 citations
    13. The extracellular matrix dictates regional competence for tumour initiation Nature · 2023 · 24 citations
    14. ADSCs inhibit photoaging‐ and photocarcinogenesis‐related inflammatory responses and extracellular matrix degradation Journal of Cellular Biochemistry · 2019 · 19 citations
    15. The microanatomy of the distal arrector pili: possible role for α1β1 and α5β1 integrins in mediating cell‐cell adhesion and anchorage to the extracellular matrix Journal of Cutaneous Pathology · 2000 · 15 citations
    16. Promotion of Hair Growth by Conditioned Medium from Extracellular Matrix/Stromal Vascular Fraction Gel in C57BL/6 Mice Stem Cells International · 2020 · 13 citations
    17. Current application of tissue-engineered dermal scaffolds mimicking the extracellular matrix microenvironment in wound healing Regenerative Therapy · 2025 · 11 citations
    18. Expression of extracellular matrix in hair follicle mesenchyme in alopecia areata British Journal of Dermatology · 1990 · 11 citations
    19. Recent Tissue Engineering Approaches to Mimicking the Extracellular Matrix Structure for Skin Regeneration Biomimetics · 2023 · 9 citations
    20. Effect of Decellularized Extracellular Matrix Bioscaffolds Derived from Fibroblasts on Skin Wound Healing and Remodeling Frontiers in bioengineering and biotechnology · 2022 · 8 citations
    21. Miliacin Associated with Polar Lipids: Effect on Growth Factors Excretion and Extracellular Matrix of the Dermal Papilla Hair Follicle Model Maintained in Survival Conditions Hair therapy & transplantation · 2016 · 5 citations
    22. Synergistic effect of microneedle-delivered extracellular matrix compound and radiofrequency on rejuvenation of periorbital wrinkles Frontiers in Medicine · 2022 · 5 citations
    23. Concentrated nanofat: a modified fat extraction promotes hair growth in mice via the stem cells and extracellular matrix components interaction Annals of Translational Medicine · 2020 · 4 citations
    24. Knockout of integrin β1 in induced pluripotent stem cells accelerates skin-wound healing by promoting cell migration in extracellular matrix Stem Cell Research & Therapy · 2022 · 3 citations
    25. Extracellular matrix‐based combination scaffold for guided regeneration of large‐area full‐thickness rabbit burn wounds upon a single application Journal of biomedical materials research. Part B, Applied biomaterials · 2021 · 3 citations
    26. [Influence of the stiffness of three-dimensionally bioprinted extracellular matrix analogue on the differentiation of bone mesenchymal stem cells into skin appendage cells]. PubMed · 2020 · 3 citations
    27. Microneedle Radiofrequency Induces Extracellular Matrix Remodeling Through Fibroblast Activation: A Histological Study in a Porcine Model Lasers in Surgery and Medicine · 2025 · 3 citations
    28. Collagen Hydrolysate from the Scales of Mozambique Tilapia (Oreochromis mossambicus) Improve Hair and Skin Health by Alleviating Oxidative Stress and Inflammation and Promoting Hair Growth and Extracellular Matrix Factors Marine drugs · 2023 · 2 citations
    29. Effects of extracellular matrix on the growth characteristics of human dermal papillae cells<i>in vitro</i> Clinical and Experimental Dermatology · 2016 · 2 citations
    30. Intraoperative Bioprinting of Human Adipose-derived Stem cells and Extra-cellular Matrix Induces Hair Follicle-Like Downgrowths and Adipose Tissue Formation during Full-thickness Craniomaxillofacial Skin Reconstruction bioRxiv (Cold Spring Harbor Laboratory) · 2023 · 1 citations