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    Glossary Extracellular Matrix Organization

    network of proteins and molecules outside cells is structured

    Extracellular Matrix Organization (ECM Organization) refers to the process by which the network of proteins and other molecules outside cells is structured and maintained. This matrix provides structural support to tissues, influences cell behavior, and plays a crucial role in wound healing, tissue repair, and overall cellular function. Proper ECM organization is essential for maintaining healthy skin and hair, and disruptions in this process can contribute to conditions like alopecia.

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    Research 30 of 1000+

    1. A 3D-printed hydrogel scaffold promotes infected diabetic wound repair via anti-inflammation, angiogenesis, and extracellular matrix remodeling Materials & Design · 2026
    2. Transcriptome Meta-Analysis Confirms the Hidradenitis Suppurativa Pathogenic Triad: Upregulated Inflammation, Altered Epithelial Organization, and Dysregulated Metabolic Signaling Biomolecules · 2022 · 13 citations
    3. O19 CYLD cutaneous syndrome tumours demonstrate increased NF-κB signalling and diminished collagen organisation. 2023
    4. Mechano-encoding hydrogel microspheres for extracellular and pericellular matrix remodeling in musculoskeletal organoids Organoid Research · 2026
    5. Comparative transcriptomic analysis of human mesenchymal stem cells derived from dental pulp and adipose tissues Journal of Stem Cells & Regenerative Medicine · 2019 · 8 citations
    6. ELL Facilitates RNA Polymerase II–Mediated Transcription of Human Epidermal Proliferation Genes 2021 · 4 citations
    7. Detecting the Mechanism behind the Transition from Fixed Two-Dimensional Patterned Sika Deer (Cervus nippon) Dermal Papilla Cells to Three-Dimensional Pattern International Journal of Molecular Sciences · 2021 · 2 citations
    8. 259 Scalp hair follicle dermal sheath fibroblasts express genes associated with promotion of skin integrity/wound healing and prevention of autoimmune responses in Recessive Dystrophic Epidermolysis Bullosa Journal of Investigative Dermatology · 2024
    9. SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair Nature Communications · 2019 · 87 citations
    10. Unraveling the ECM-Immune Cell Crosstalk in Skin Diseases Frontiers in Cell and Developmental Biology · 2019 · 97 citations
    11. The Epithelial Stem Cell Niche in Skin Elsevier eBooks · 2017 · 9 citations
    12. An injectable photo-crosslinking silk hydrogel system with biphasic release of BTXA and 5-Fu promotes scarless wound healing RSC Advances · 2026
    13. 464 Spatial transcriptomics links gene expression profiles to functional and structural traits of darkly pigmented skin Journal of Investigative Dermatology · 2025
    14. EVALUATION OF EFFICACY OF FOLLICULAR UNIT EXCISION VERSUS FOLLICULAR UNIT EXCISION WITH NANOFAT IN SCARS IN HAIRY AREAS ALEXMED ePosters · 2025
    15. 707 Guiding skin organoid generation via extracellular matrix cues and spatially controlled morphogen gradients 2022
    16. Efficient Generation of Skin Organoids from Pluripotent Cells via Defined Extracellular Matrix Cues and Morphogen Gradients in a Spindle‐Shaped Microfluidic Device 2024
    17. Hardwiring Stem Cell Communication through Tissue Structure Cell · 2016 · 82 citations
    18. Microneedle-Assisted Penetration of Fibronectin Nanogels for Enhanced Anti-Aging Healthcare and Diabetic Wound Healing ACS Nano Medicine · 2026
    19. Progenitor Cell Dynamics in Androgenetic Alopecia: Insights from Spatially Resolved Transcriptomics International Journal of Molecular Sciences · 2025
    20. Matrix remodelling and MMP expression/activation are associated with hidradenitis suppurativa skin inflammation Experimental Dermatology · 2019 · 51 citations
    21. Progress and perspectives on hydrogel-assisted skin organoids Organoid Research · 2026
    22. 1270 Fibroproliferative genes are preferentially expressed in central centrifugal cicatricial alopecia Journal of Investigative Dermatology · 2018 · 3 citations
    23. Identification of key genes in type 2 diabetes‐induced erectile dysfunction rats with stem cell therapy through high‐throughput sequencing and bioinformatic analysis Andrologia · 2021 · 2 citations
    24. Matrisomal components involved in regenerative wound healing in axolotl and <i>Acomys</i>: implications for biomaterial development Biomaterials Science · 2023
    25. Hair follicle stem cells as a skin‐organizing signaling center during adult homeostasis The EMBO Journal · 2021 · 25 citations
    26. Expression of an Olfactomedin-Related Gene in Rat Hair Follicular Papilla Cells 2005 · 10 citations
    27. Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 2 citations
    28. Basement membrane components define the microenvironment of aggregated fibroblasts in the skin and support their aggregation in vitro bioRxiv (Cold Spring Harbor Laboratory) · 2025
    29. High-throughput screening of 3D co-culture hair follicle mimetic tissue with enhanced ECM for the screening of hair growth promoting compounds Biomaterials Research · 2024
    30. 1456 Tensor effect of anigozanthos flavidus flower extract: Modulation of tenascin-X to regenerate the skin Journal of Investigative Dermatology · 2018