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    Glossary Epidermal Keratinocytes

    cells in the skin's outer layer producing protective keratin

    Epidermal keratinocytes are the primary type of cells found in the outermost layer of the skin, known as the epidermis. These cells produce keratin, a tough, protective protein that helps the skin act as a barrier against environmental damage, pathogens, and water loss.

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    1. Interleukin-1 Induces Transcription of Keratin K6 in Human Epidermal Keratinocytes 2001 · 90 citations
    2. Selective Ablation of Ctip2/Bcl11b in Epidermal Keratinocytes Triggers Atopic Dermatitis-Like Skin Inflammatory Responses in Adult Mice PLoS ONE · 2012 · 40 citations
    3. Epidermal keratinocytes initiate wound healing and pro-inflammatory immune responses following percutaneous schistosome infection 2015 · 39 citations
    4. GRHL3 binding and enhancers rearrange as epidermal keratinocytes transition between functional states PLOS Genetics · 2017 · 38 citations
    5. The Autoimmune Regulator (AIRE), Which Is Defective in Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Patients, Is Expressed in Human Epidermal and Follicular Keratinocytes and Associates With the Intermediate Filament Protein Cytokeratin 17 ˜The œAmerican journal of pathology · 2011 · 24 citations
    6. Isolating Hair Follicle Stem Cells and Epidermal Keratinocytes from Dorsal Mouse Skin Journal of Visualized Experiments · 2016 · 23 citations
    7. Impaired Keratinocyte Proliferative and Clonogenic Potential in Transgenic Mice Overexpressing 14-3-3σ in the Epidermis Journal of Investigative Dermatology · 2011 · 15 citations
    8. YAP/TAZ Signalling Controls Epidermal Keratinocyte Fate International Journal of Molecular Sciences · 2024 · 14 citations
    9. Isolating Hair Follicle Stem Cells and Epidermal Keratinocytes from Dorsal Mouse Skin Journal of Visualized Experiments · 2016 · 13 citations
    10. Tenascin-C expressing touch dome keratinocytes exhibit characteristics of all epidermal lineages Science Advances · 2024 · 5 citations
    11. The Simplest Protocol for Rapid and Long-Term Culture of Primary Epidermal Keratinocytes from Human and Mouse Methods in molecular biology · 2019 · 2 citations
    12. A Mouse Model for Conditional Expression of Activated β-Catenin in Epidermal Keratinocytes Transgenic Research · 2024 · 1 citations
    13. Skin epidermal keratinocyte p53 induces food uptake upon UV exposure Frontiers in Behavioral Neuroscience · 2023 · 1 citations
    14. 766 H3K9me3 methyltransferase SETDB1 controls retrotransposon silencing, DNA methylation, constitutive heterochromatin maintenance and 3D-chromatin structure in epidermal keratinocytes 2023
    15. 532 Unexpected expression of hemoglobin α as an endogenous antioxidant in epidermal keratinocytes 2022
    16. 265 Loss of Langerhans cells in scar lesion of lichen planopilaris is caused by downregulation of integrin αvβ6 in the epidermal keratinocytes 2017
    17. [Difference between the hair follicle cell and epidermal keratinocyte in vitro]. PubMed · 1990
    18. α-parvin is required for epidermal morphogenesis, hair follicle development and basal keratinocyte polarity PloS one · 2020 · 7 citations
    19. Experimental Modulation of the Differentiated Phenotype of Keratinocytes from Epidermis and Hair Follicle Outer Root Sheath and Matrix Cells Annals of the New York Academy of Sciences · 1991 · 31 citations
    20. Potassium Channel Openers Stimulate DNA Synthesis in Mouse Epidermal Keratinocyte and Whole Hair Follicle Cultures Skin Pharmacology and Physiology · 1993 · 31 citations
    21. Epidermal keratinocyte stem cells: their maintenance and regulation Seminars in cell biology · 1992 · 25 citations
    22. Physiological and retinoid-induced proliferations of epidermis basal keratinocytes are differently controlled EMBO journal · 2002 · 127 citations
    23. Expression of μ-Opiate Receptor in Human Epidermis and Keratinocytes Journal of Investigative Dermatology · 1998 · 111 citations
    24. Recent advances in the epidermal growth factor receptor/ligand system biology on skin homeostasis and keratinocyte stem cell regulation Journal of Dermatological Science · 2013 · 97 citations
    25. Epidermal expression of the truncated prelamin A causing Hutchinson-Gilford progeria syndrome: effects on keratinocytes, hair and skin Human Molecular Genetics · 2008 · 48 citations
    26. Coactivator MED1 Ablation in Keratinocytes Results in Hair-Cycling Defects and Epidermal Alterations 2011 · 41 citations
    27. Modulation of the differentiated phenotype of keratinocytes of the hair follicle and from epidermis Journal of Dermatological Science · 1994 · 41 citations
    28. Keratinocyte-derived follistatin regulates epidermal homeostasis and wound repair Laboratory investigation · 2008 · 28 citations
    29. Breast cancer resistance protein identifies clonogenic keratinocytes in human interfollicular epidermis Stem Cell Research & Therapy · 2015 · 14 citations
    30. Cell Density-Dependent Upregulation of PDCD4 in Keratinocytes and Its Implications for Epidermal Homeostasis and Repair International Journal of Molecular Sciences · 2015 · 10 citations