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The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Adding anti-Müllerian hormone to PCOS criteria lowers the number of women diagnosed.

Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.

About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Oral antiandrogens effectively treat female hair loss, with better results in higher hair loss grades.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Low-Level Laser Therapy is effective and safe for hair growth with minimal side effects.

Low iron levels may be linked to some types of hair loss in women.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Finasteride helps hair growth but may cause sexual side effects.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.