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This study suggests that residues Val-889 and Arg-752 in the androgen receptor's steroid binding domain are crucial for NH2-/carboxyl-terminal interaction, affecting receptor stability and function.

This study characterized the CYP154C7 enzyme from *Streptomyces* sp. PAMC26508, highlighting its ability to hydroxylate steroids efficiently, particularly androstenedione, and identified key amino acids important for substrate selectivity and catalytic efficiency.

In this animal study, finasteride exposure led to impaired spermatogenesis in rats, while the novel compound DA-9401, derived from three medicinal herbs, demonstrated potential in improving sperm parameters and reducing testicular apoptosis when used alone or with finasteride.

New method quickly and accurately measures dexpanthenol in hair products.

This study found that inhibiting the ATR kinase with VE-822 impairs DNA repair capability in quiescent human keratinocytes exposed to solar-simulated UV radiation, suggesting ATR's critical role in facilitating effective DNA damage repair and cellular recovery under UV stress conditions.

This study found that DEFB1 polymorphisms, specifically the rs1800972 CG and GG genotypes, may predict susceptibility to and severity of alopecia areata.

This case report identified two new SLC39A4 mutations in twin patients with acrodermatitis enteropathica, suggesting that different mutations in this gene may lead to varying clinical manifestations of the disorder.

This study found that Compound Diandao Pulvis Drug Facial Mask improved some signs of acne in a rabbit ear model, but its effects were not significantly different from tretinoin cream.

This article contains no abstract or new findings.

In this study, high-dose oral administration of Ramania leaf ethanol extract in Wistar rats resulted in no significant acute toxicity symptoms, though gastric ulcers and hair loss were observed. The extract is classified as non-toxic under specified guidelines, with an LD50 greater than 5000 mg/kg.

Among individuals with skin types II and III, this study found the 755 nm laser more effective for axillary hair removal than the dual-wavelength laser, with a better safety profile and enduring results up to 12 months.

A patient's skin rash did not affect the area where a previous viral rash was healing, suggesting a rare immune response.

The document's conclusion cannot be summarized because the content is not available.

Rare earth elements are crucial in medical imaging and cancer treatment.

This study found that in male androgenic alopecia, the androgen receptor coactivator ARA70/ELE1 exhibits differential expression patterns, suggesting its involvement in the condition.

This study found that a novel missense mutation in the vitamin D receptor caused hereditary 1,25-dihydroxyvitamin D-resistant rickets with alopecia by disrupting protein function, highlighting the importance of DNA binding in hair development.

In this study, researchers identified a unique Arg30stop mutation in the vitamin D receptor gene that causes hereditary vitamin D-resistant rickets in a young French-Canadian boy by truncating the receptor and causing hormone resistance.

In this retrospective study, combining TACE with Donafenib showed promising results as a first-line treatment for Chinese patients with unresectable hepatocellular carcinoma, yielding a median progression-free survival of 12.8 months and a one-year overall survival rate of 87.5%, along with a favorable safety profile.

Farudodstat may effectively treat alopecia areata without harmful side effects.

This study found that among men unresponsive to finasteride for androgenic alopecia, 56.25% showed significant hair improvement after six months of dutasteride treatment with reasonable adverse effects.

This study highlights the phenotypic variability in 5 patients with Woodhouse-Sakati syndrome carrying the c.436delC mutation, suggesting a broader range of clinical presentations than previously recognized.

This study observed that the rs231775 CTLA4 genetic variant was more prevalent in Alopecia Areata patients than controls, particularly among those with severe disease.

This study concluded that using an erbium:YAG laser for calvarium trepanation and granulation tissue induction is comparable to the rose head burr, offering a beneficial alternative method.

This study found that the AR-E211 A allele is associated with a lower risk of both metastatic prostate cancer and androgenetic alopecia in an Australian population.

This study found no association between the -866G/A polymorphism in the UCP2 gene and the development of polycystic ovary syndrome.