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Advanced human skin models improve drug development and could replace animal testing.

Some skin lymphomas can look like common skin issues and need careful testing to diagnose correctly.

SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.

Thermoresponsive nanogels show promise for delivering medicine through the skin but need more safety testing and regulatory approval before clinical use.

The photographic method for measuring facial hair density is reliable and valid but needs further testing on different hair densities and skin colors.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.

AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

Skin reactions to drugs are common and can be deadly, usually requiring stopping the drug and may be better prevented with genetic testing in the future.

An 11-year-old Greek girl was diagnosed with a rare genetic disorder, highlighting the importance of genetic testing and family history.

Ionizing radiation damages human hair follicles by stopping cell growth, causing cell death, disrupting color, and increasing stress and damage markers.

Mutation in hairless gene may increase hair loss risk.

A new type of pachyonychia congenita linked to a specific keratin gene mutation was found in two Pakistani families.

Mutation in hairless gene may increase hair loss risk.

The baby’s hair loss was due to a rare genetic condition, not treatable by usual methods.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

Melatonin affects mouse skin and may regulate skin functions.

Kennedy's disease leads to muscle weakness without a cure, but exercise and managing symptoms may help patients live a normal lifespan.

Children generally have milder SARS symptoms than adults, with good outcomes and no deaths reported, but long-term effects are unclear.

The gene p53 is crucial for removing damaged cells to allow for healthy tissue renewal.

The conclusion is that genetic testing is important for diagnosing and treating various genetic hair disorders.

Using 17-hydroxyprogesterone levels to diagnose nonclassic congenital adrenal hyperplasia can result in many incorrect diagnoses.