April 2021 in “Journal of Investigative Dermatology” In this study, researchers observed that different ERK signal activation dynamics during hair follicle regeneration are linked to cell fate specification and are affected by distinct upstream signaling pathways.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, mouse sebaceous glands were found to require nerves for growth during active hair cycles, suggesting a nerve-dependent sebaceous gland cycle coordinated with hair growth.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, the researchers observed that post-radiation hair follicle repair in 3D architecture occurs through independent, long-range cell movements along the basal surface, resembling 2D healing processes.
April 2021 in “Journal of Investigative Dermatology” This study developed a transgenic mouse model to explore androgenetic alopecia, finding that inducible COX2 expression led to sebaceous gland changes and hair miniaturization, with reversible effects upon reducing COX2.
June 2007 in “Journal of Investigative Dermatology” Title change to "Central Centrifugal Cicatricial Alopecia (CCCA)"; common in African American women; hair-grooming methods may contribute; no effective therapy found; trials needed.
30 citations
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November 1996 in “Archives of Dermatology” This report describes cases of increased hair loss and scalp sunburns in patients using 3% minoxidil and 0.01% tretinoin, suggesting caution with tretinoin use on sunny days.
17 citations
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August 2012 in “Journal of Medical Genetics” This article reviews the genetic mutations associated with hypohidrotic ectodermal dysplasia and reports no new clinical results; the authors highlight the roles of EDA gene isoforms and related receptors.
2 citations
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January 2013 in “Elsevier eBooks” The document explains the genetic causes and characteristics of inherited hair disorders.
1 citations
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April 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that inhibiting mTORC1 activity with rapamycin increased both hair growth and pigmentation in human scalp hair follicles, suggesting a potential strategy for treating greying and hair loss.
1 citations
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April 2021 in “Journal of Investigative Dermatology” This study found that Manganese PCA, Cinchona succirubra, and Leontopodium alpinum extracts may promote hair growth by enhancing VEGF secretion and activating the Wnt/b-catenin pathway in Human Hair Follicle Dermal Papilla Cells.