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    Glossary Epidermal Differentiation Markers

    specific proteins indicating skin cell development stages

    Epidermal differentiation markers are specific proteins or molecules found in the skin that indicate the various stages of skin cell development and maturation. These markers help scientists and doctors understand how skin cells evolve from their initial form to their final, specialized state, which is crucial for maintaining healthy skin and diagnosing skin disorders.

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    1. The cDNA-deduced amino acid sequence for trichohyalin, a differentiation marker in the hair follicle, contains a 23 amino acid repeat. 1990 · 39 citations
    2. The changes in the expression levels of follicular markers in keratoacanthoma depend on the stage: keratoacanthoma is a follicular neoplasm exhibiting infundibular/isthmic differentiation without expression of CK15 Journal of Cutaneous Pathology · 2014 · 28 citations
    3. 576 A preliminary study of melanogenic markers in the differentiation of the human hair follicle melanin unit 2022
    4. Cytokeratins as Markers of Follicular Differentiation American Journal of Dermatopathology · 2001 · 121 citations
    5. Neutrophil gelatinase‐associated lipocalin is a marker for dysregulated keratinocyte differentiation in human skin Experimental dermatology · 2002 · 96 citations
    6. Defining the complex epithelia that comprise the canine claw with molecular markers of differentiation Veterinary Dermatology · 2009 · 6 citations
    7. Histochemical and Immunohistochemical Markers for Human Eccrine and Apocrine Sweat Glands: An Aid for Histopathologic Differentiation of Sweat Gland Tumors Journal of Investigative Dermatology Symposium Proceedings · 2001 · 73 citations
    8. Nestin is a marker of unipotent embryonic and adult progenitors differentiating into an epithelial cell lineage of the hair follicles Scientific reports · 2022 · 1 citations
    9. Nestin as a marker of unipotent epithelial progenitor cell differentiation into outer root sheath keratinocytes in embryonic and adult hair follicles Research Square (Research Square) · 2022
    10. 602 Sox13 is a novel marker for hair follicle development and differentiation Journal of Investigative Dermatology · 2019
    11. Keratin expression in the normal nail unit: markers of regional differentiation British Journal of Dermatology · 2000 · 119 citations
    12. Specific Keratins and their Associated Proteins as Markers for Hair Follicle Differentiation 1988 · 7 citations
    13. Upregulation of genes orchestrating keratinocyte differentiation, including the novel marker gene <i>ID2</i>, by contact sensitizers in human bulge‐derived keratinocytes Journal of Biochemical and Molecular Toxicology · 2010 · 6 citations
    14. GATA3 inhibits proliferation and induces expression of both early and late differentiation markers in keratinocytes of the human epidermis Archives of Dermatological Research · 2013 · 24 citations
    15. LB1019 The early region of trichodysplasia spinulosa polyomavirus drives proliferation, altered differentiation, and ectopic expression of hair follicle differentiation markers in interfollicular tail epidermis 2022
    16. LB1256 TRIV-509, a dual inhibitor of KLK5 and KLK7, rapidly improves barrier integrity and markers of epidermal differentiation in atopic dermatitis skin explants Journal of Investigative Dermatology · 2025
    17. Expression of hair-related keratins in a soft epithelium: Subpopulations of human and mouse dorsal tongue keratinocytes express keratin markers for hair-, skin- and esophageal-types of differentiation Experimental Cell Research · 1989 · 128 citations
    18. Differentiation of nestin-negative human hair follicle outer root sheath cells into neurons in vitro Molecular Medicine Reports · 2017 · 5 citations
    19. <i>FGF20</i> Secreted From Dermal Papilla Cells Regulate the Proliferation and Differentiation of Hair Follicle Stem Cells in Fine‐Wool Sheep Journal of Animal Physiology and Animal Nutrition · 2024 · 3 citations
    20. Abstract 5219: The role of MEK and Antizyme in keratinocyte stem cell expansion and differentiation Cancer Research · 2012 · 1 citations
    21. Keratin Promotes Differentiation of Keratinocytes Seeded on Collagen/Keratin Hydrogels Bioengineering · 2022 · 1 citations
    22. Proliferation and Differentiation of Human Hair Follicle Stem Cells on Chitosan-Skin Engineered Template in Vitro International Journal on Advanced Science, Engineering and Information Technology · 2017
    23. 102 EZH2 is required for human hair follicle growth and epidermal differentiation Journal of Investigative Dermatology · 2016
    24. Defining and targeting differentiation of non-melanoma skin cancer 2014
    25. Dedifferentiation of committed epithelial cells into stem cells in vivo Nature · 2013 · 551 citations
    26. Differentiation of Human Dermal Mesenchymal Stem Cells into Cardiomyocytes by Treatment with 5-Azacytidine: Concept for Regenerative Therapy in Myocardial Infarction ISRN Stem Cells (Online) · 2013 · 9 citations
    27. Androgens induce sebaceous differentiation in sebocyte cells expressing a stable functional androgen receptor 2015 · 31 citations
    28. Hair follicle stem cells:<i>In vitro</i>and<i>in vivo</i>neural differentiation World journal of stem cells · 2015 · 25 citations
    29. Transgenic Kallikrein 14 Mice Display Major Hair Shaft Defects Associated with Desmoglein 3 and 4 Degradation, Abnormal Epidermal Differentiation, and IL-36 Signature 2020 · 15 citations
    30. Nuclear Factor I-C promotes proliferation and differentiation of apical papilla-derived human stem cells in vitro Experimental Cell Research · 2015 · 24 citations