4 citations
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January 1989 This study found that growth affects selenium deposition in hair, nails, and other tissues of adult and weanling rats, indicating dietary and physiological factors may influence selenium levels.
April 2017 in “The FASEB journal” This study suggests that selenium deprivation in mice accelerates age-related degeneration but paradoxically promotes longevity, potentially decoupling healthspan from lifespan.
5 citations
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July 2019 in “Nutrients” This study found that boys in Mexico City with selenium intake below the recommended dietary allowance had lower odds of progressing to advanced stages of pubertal development, while no association was observed in girls.
1 citations
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January 2018 in “Molecular and integrative toxicology” This review discusses the dual role of selenium in human health, highlighting both the dangers of deficiency and potential toxicity from over-supplementation, without presenting new clinical results.
35 citations
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January 2001 in “Journal of Animal Science” This study found that dietary selenium levels above 5 ppm can lead to selenosis in pigs, with white-haired pigs showing alopecia sooner than dark-haired pigs.
27 citations
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June 2010 in “Journal of the American Academy of Dermatology” Excessive selenium in supplements can cause hair loss and nail issues.
55 citations
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February 1990 in “Journal of Nutrition” This study observed that selenium retention in rat hair and nails was influenced by the chemical form of dietary selenium and methionine status, suggesting caution when using these tissues to assess selenium status.
February 2024 in “Animals” This study found that supplementing pregnant Hanshan white cashmere goats' diets with selenium yeast led to higher birth weights, improved cashmere quality and yield, and enhanced hair follicle development in their offspring, possibly through increased antioxidant capacity.
382 citations
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February 2010 in “Archives of Internal Medicine” This study identified that high concentrations of selenium in a liquid dietary supplement caused a widespread outbreak of poisoning, revealing the importance of stricter manufacturing standards.
30 citations
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September 2016 in “Aging Cell” This study found that selenium deficiency in mice accelerated age-related conditions and metabolic decline but unexpectedly promoted longevity, suggesting low selenium levels might separate healthspan and lifespan.
16 citations
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December 2005 in “Journal of Animal Physiology and Animal Nutrition” This study found that both low and high dietary selenium levels reduced hair growth in adult dogs, with optimal growth observed at mid-range selenium concentrations.
6 citations
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March 2011 in “Experimental Dermatology” This study found that an imbalance of selenium in a C57BL/6 mouse model led to hair loss with color change and was linked with changes in hair follicle apoptosis markers.
May 1990 in “ThinkTech (Texas Tech University)” This review discusses the cytotoxic effects of various selenium compounds on human mammary tumor cells and explores the impact of selenium and magnesium in dietary studies with nude mice, reporting no new clinical results.
January 2024 in “Ageing & longevity” This study observed low levels of zinc, copper, iron, and selenium in the plasma and hair of Ukrainian adults, suggesting a need for better nutritional interventions; it highlighted higher hair zinc levels in individuals with COVID-19 history potentially due to more frequent zinc supplementation.
June 2025 in “Annals of the Rheumatic Diseases” This study found that pregnant women with rheumatic diseases had sufficient energy and macronutrient intake, but showed a high prevalence of overweight and obesity, with selenium intake exceeding safe levels, which may lead to potential side effects.
February 2023 in “American Journal of Biomedical and Life Sciences” The researchers reported that hair bio element median derivatives bioassay is an effective and reliable method for evaluating the nutritional status of various bio elements, offering a non-invasive approach for nutritional health surveillance and precision medicine.
13 citations
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January 2012 in “International Journal of Trichology” This study reports a case where excessive consumption of "paradise nuts" led to acute selenium toxicity and massive hair loss.
This source highlights concerns about the safety and efficacy of dietary supplements marketed for hair loss, citing a lack of FDA testing and potential risks such as adverse side effects, interference with medical tests, and withholding of ingredient information.
January 2017 in “International journal of clinical & experimental dermatology” This review discusses how nutritional and lifestyle modifications, including antioxidant use, may enhance hair growth and prevent hair loss without the need for Finasteride, but provides no new clinical findings.
11 citations
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January 2016 in “BMC veterinary research” This study found that urinary selenium to creatinine ratio and serum selenium concentrations quickly respond to changes in dietary selenium, making them useful biomarkers for assessing selenium status in dogs.
78 citations
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December 2011 in “Clinical toxicology” This study describes a case series of nine patients experiencing symptoms of selenium toxicity after consuming a liquid dietary supplement with an excess amount of selenium.
18 citations
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September 2011 in “Livestock science” This study found that maternal Nano-Se supplementation in cashmere goats improved antioxidant status and promoted secondary hair follicle development in fetuses at 110 days.
This study found that certain dietary changes, such as a low glycemic load diet for men and specific supplements for women, may improve acne, while chocolate, whey proteins, and dairy products are linked to worsened symptoms in both genders.
76 citations
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April 2002 in “Urology” This review examines the use of selenium and vitamin E supplements for reducing prostate cancer risk, finding mixed evidence that suggests benefits may be limited to individuals with specific risk factors, like low baseline levels or smoking history, rather than broadly applicable.
21 citations
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June 1991 in “Journal of Inherited Metabolic Disease” This case report observed that a selenium-deficient diet in a child with propionic acidaemia led to macrocytosis and hair abnormalities, which improved with selenium supplementation.
February 2024 in “IntechOpen eBooks” This chapter reviews nutritional strategies for managing polycystic ovary syndrome, emphasizing dietary adjustments and lifestyle changes, but it does not report new clinical findings.
This book chapter discusses the mechanisms and prevention of selenium toxicity in livestock and reports no new experimental results; it emphasizes reducing selenium in the human food chain through animal products.
241 citations
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January 2001 in “Reviews on Environmental Health” This review discusses the various adverse health effects of chronic selenium exposure in humans, including effects on endocrine and immune function, and suggests current exposure limits may be insufficient.
This study highlights the increasing association between popular diets, unregulated supplements, and various skin disorders, emphasizing the need for clinicians to thoroughly assess dietary histories to manage nutrition-related skin issues effectively.
July 2018 in “International journal of clinical & experimental dermatology” This narrative review describes the components of human hair and their nutritional importance but reports no clinical results; the authors suggest dietary sulfur amino acids are essential for hair health.