research Desmoglein 3-Mediated Mechanical Transadhesion Controls Epithelial Stem Cell Quiescence
Desmoglein 3 is important for keeping hair follicle stem cells inactive and maintaining their special properties.
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330-337 / 337 resultsresearch The Role of Natural Killer Cells in Autoimmune Blistering Diseases
Natural killer cells play a key role in autoimmune skin diseases like pemphigus vulgaris.
research Development of a Desmocollin-3 Active Mouse Model Recapitulating Human Atypical Pemphigus
Anti-Desmocollin 3 antibodies can cause pemphigus-like symptoms in mice.
research Uncoupling Desmosomal Cadherin Adhesion Activates Quiescent Hair Follicle Stem Cells and Orchestrates Self-Organized Regeneration Through Outside-In Signaling
Disrupting a specific protein's function in hair follicle stem cells triggers their activation and a self-healing process.
research SnapshotDx Quiz: November 2017
Pemphigus vulgaris involves specific immune cells and B cells that produce antibodies causing skin blisters.
research Comparison of Sensitivity Patterns of Direct Immunofluorescence on Perilesional Skin and Plucked Hair in Pemphigus Vulgaris
Plucked hair can help diagnose pemphigus vulgaris early.
research LFA-1 Blockade Prevents the Onset of Alopecia Areata in C3H/HeJ Mice
Blocking LFA-1 prevents hair loss in mice.