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    Glossary Dermal Condensate

    cluster of specialized skin cells initiating hair follicle formation

    Dermal condensate refers to a cluster of specialized cells in the skin's dermis layer that play a crucial role in the formation of hair follicles. These cells signal to the overlying epidermal cells to start the process of hair follicle development, making them essential for hair growth and regeneration.

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    1. Rapid mechanosensitive migration and dispersal of newly divided mesenchymal cells aid their recruitment into dermal condensates PLoS biology · 2023 · 2 citations
    2. 872 Dermal Wnt/β-catenin signaling controls hair follicle dermal condensate size during development Journal of Investigative Dermatology · 2017
    3. Decision letter: Hair follicle dermal condensation forms via Fgf20 primed cell cycle exit, cell motility, and aggregation 2018
    4. Author response: Hair follicle dermal condensation forms via Fgf20 primed cell cycle exit, cell motility, and aggregation 2018 · 1 citations
    5. 676 Wnt and SHH interact to determine hair follicle dermal condensate fate Journal of Investigative Dermatology · 2024
    6. 1362 The role of Fgf20 in establishing the hair follicle dermal condensate Journal of Investigative Dermatology · 2018
    7. Wnt1a maintains characteristics of dermal papilla cells that induce mouse hair regeneration in a 3D preculture system Journal of Tissue Engineering and Regenerative Medicine · 2015 · 23 citations
    8. 1338 Dermal Wnt/β-catenin activation tunably controls hair follicle initiation Journal of Investigative Dermatology · 2018
    9. 0140 Delineating key molecular programs that induce hair-follicle-inductive dermal fibroblasts using a novel single-cell genomic approach Journal of Investigative Dermatology · 2025
    10. Generating LacZ-reporter transgenic mice to identify α1 (XIX) Collagen (Col19a1) expression in Dermal Papilla Cells Benha Veterinary Medical Journal · 2016
    11. Transdifferentiation of corneal epithelium into epidermis occurs by means of a multistep process triggered by dermal developmental signals Proceedings of the National Academy of Sciences · 2005 · 130 citations
    12. The origins of skin diversity: lessons from dermal fibroblasts Development · 2022 · 6 citations
    13. An Integrated Transcriptome Atlas of Embryonic Hair Follicle Progenitors, Their Niche, and the Developing Skin Developmental cell · 2015 · 173 citations
    14. CD10 and CD34 in fetal and adult human hair follicles: dynamic changes in their immunohistochemical expression during embryogenesis and hair cycling British Journal of Dermatology · 2008 · 25 citations
    15. Generation of human-induced pluripotent stem cell-derived adherent 3-dimensional skin hair-follicle organoids Organoid · 2022 · 2 citations
    16. Fate Before Function: Specification of the Hair Follicle Niche Occurs Prior to its Formation and Is Progenitor Dependent bioRxiv (Cold Spring Harbor Laboratory) · 2018 · 2 citations
    17. A single-cell transcriptome atlas during Cashmere goat hair follicle morphogenesis bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 1 citations
    18. Mesenchyme governs hair follicle induction bioRxiv (Cold Spring Harbor Laboratory) · 2023
    19. 1345 A single-cell RNA map of perinatal developing mouse skin Journal of Investigative Dermatology · 2023
    20. 877 Small T antigen from a folliculotropic polyomavirus activates canonical Wnt/β-catenin signaling in vivo Journal of Investigative Dermatology · 2017
    21. Novel tissue mechanics-guided cellular flows drive the formation of feather follicles The EMBO Journal · 2026
    22. Novel Tissue Mechanics-Guided Cellular Flows Enable the Evolution of Feather Follicles 2025
    23. Exosomes serve as a crucial mediator of epithelial–fibroblast communication during hair follicle morphogenesis in cashmere goats Comparative Biochemistry and Physiology Part D Genomics and Proteomics · 2024
    24. 660 Complex cellular flows shape feather follicle topology Journal of Investigative Dermatology · 2024
    25. The Historical Studies Underpinning the Concept of Hair Follicle Neogenesis Springer eBooks · 2022
    26. 090 Stromal re-organization in hair follicle development and cancer suppression 2016
    27. Newly born mesenchymal cells disperse through a rapid mechanosensitive migration bioRxiv (Cold Spring Harbor Laboratory) · 2023
    28. 1387 Identifying the key niche signals for hair follicle formation Journal of Investigative Dermatology · 2018
    29. BMP2 and BMP7 play antagonistic roles in feather induction Development · 2008 · 88 citations
    30. Dynamic expression patterns of tenascin, proteoglycans, and cell adhesion molecules during human hair follicle morphogenesis Developmental dynamics · 1994 · 67 citations