research Update on Hormonal Therapy in Hidradenitis Suppurativa
Hormonal therapies, especially antiandrogens, can help manage Hidradenitis Suppurativa.
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research Selective Follicular Targeting by Modification of the Particle Sizes
Medium-sized particles penetrate hair follicles better than smaller or larger ones, which could improve delivery of skin treatments.
research Penetration and Distribution of Three Lipophilic Probes in Human Skin Focusing on the Hair Follicle
Medium lipophilic substances penetrate skin best, and adding ethanol can increase delivery to hair follicles.
research Microneedles Mediated Bioinspired Lipid Nanocarriers for Targeted Treatment of Alopecia
A new hair loss treatment uses tiny needles to deliver a drug-loaded lipid carrier, promoting hair growth more effectively than current treatments.
research Triggering of Drug Release of Particles in Hair Follicles
New method uses hair follicles to deliver drugs deep into the skin.
research Dissolving Microneedles: Applications and Growing Therapeutic Potential
Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.
research Hair Follicle Targeting With Curcumin Nanocrystals: Influence of Formulation Properties on Penetration Efficacy
Curcumin nanocrystals in simple gels effectively penetrate hair follicles, but humectants can reduce this efficacy.
research Gas-propelled anti-hair follicle aging microneedle patch for the treatment of androgenetic alopecia
The study introduces a novel gas-propelled microneedle patch loaded with ferrum-chelated puerarin/quercetin nanoparticles (PQFN) as an innovative treatment for androgenetic alopecia (AGA). This system enhances drug delivery to hair follicles, addressing oxidative stress and vascularization deficiencies that contribute to hair follicle aging. PQFN rejuvenates testosterone-induced senescence in dermal papilla cells by reducing reactive oxygen species, restoring mitochondrial function, and promoting angiogenesis. The gas-propelled microneedles improve drug penetration into deeper skin layers, leading to higher drug accumulation in hair follicles. Pharmacodynamic studies in an AGA mouse model demonstrated that PQFN-loaded microneedles significantly increased hair coverage by alleviating oxidative stress, promoting angiogenesis, and rejuvenating senescent cells, offering a promising anti-aging treatment strategy for AGA.
research Iron Deficiency Anemia Pruritus: A Review with Proposed Mechanisms of Action
Iron deficiency anemia can cause itching, which often improves with iron supplements.
research Pilosebaceous Unit: Structure, Function, and Disorders
Androgens and other hormones affect hair growth and skin conditions like acne.
research Dermatologic Applications of Direct-to-Consumer Genomic Analysis
Living near more dermatologists and using certain cancer screening tests lowers the chance of being diagnosed with advanced skin cancer.
research Changing Incidence Trends of Cutaneous B-Cell Lymphoma
The number of new cases of cutaneous B-cell lymphoma has leveled off since the early 2000s, and survival rates have improved since 1973.
research Pharmacology of Anabolic Steroids
Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.
research Interferon Alfa-2a in the Treatment of Cutaneous T Cell Lymphoma
Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.
research A Pilot Study of ICG Laser Therapy of Acne Vulgaris: Photodynamic and Photothermolysis Treatment
ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.
research Pilosebaceous Physiology in Relation to Hirsutism and Acne
Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.
research Hair Counts from Normal Scalp Biopsy in Taiwan
The conclusion is that normal scalp hair counts for Taiwanese people were established, showing age-related differences but not sex or scalp location differences.
research Beau's Lines
Beau's lines and hair loss in a patient were linked to severe stress on the body.
research Fixed-Drug Eruption Due to Dextromethorphan
A woman had a skin reaction from a cough suppressant, dextromethorphan, which is a new cause of fixed-drug eruption.
research Head and Neck Reconstruction: Management and Techniques for Burns
The document concludes that individualized reconstruction plans are essential for improving function and appearance after head and neck burns.
research Be Damned or Be Beautiful: The History of Alopecia and Wigs
Wigs are still a popular solution for hair loss to maintain a youthful look.
research An Atlas of Hair Pathology with Clinical Correlations
The book is a detailed guide on hair and scalp diseases, useful for dermatopathologists.
research Foundations of Evidence-Based Medicine
The book has valuable information but is hard to read due to poor writing.
research Forensic Medicine: Clinical and Pathological Aspects
The book is a comprehensive guide for forensic practitioners and exam candidates.
research Survival Skills for Doctors and Their Families
Doctors should set boundaries and seek outside help for family medical issues.
research Ethics Consultation: From Theory to Practice
The book is a useful reference for forensic medicine with some areas needing expansion for multicultural relevance.
research Patients, Power and Responsibility
The document concludes that while some advocate for a patient voucher system, it may be unequal and current healthcare reforms should be given a chance, and it also recommends various medical books for their comprehensive coverage and advice on specific health issues.
research The Breast Cancer Wars: Fear, Hope and the Pursuit of a Cure in Twentieth Century America
Understanding breast cancer requires considering both medical advancements and social influences.
research Technology Transfer And The Climate Of Change
The document concludes that a Quality Management System is crucial for maintaining product quality through innovation and proper technology transfer in the pharmaceutical industry.
research WNT Signaling in Disease
The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.