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Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Researchers created human hair follicles using a new method that could help treat hair loss.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Low-Level Laser Therapy is effective and safe for hair growth with minimal side effects.

Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Estrogen therapy can reduce skin aging but has cancer risks.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Finasteride effectively blocks enzyme causing male pattern baldness.

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

Silver nanoparticles coated with substances like PEG showed strong antibacterial effects and improved wound healing when used in hydrogels.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

The BASP classification is a detailed and accurate way to categorize hair loss in both men and women.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.