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    Glossary Cytokine-Targeted Therapies

    treatments that modulate proteins to reduce inflammation and autoimmune diseases

    Cytokine-Targeted Therapies are treatments designed to modulate the activity of cytokines, which are small proteins that play a crucial role in cell signaling, particularly in immune responses. By targeting specific cytokines, these therapies aim to reduce inflammation and treat autoimmune diseases, such as rheumatoid arthritis and psoriasis, as well as certain types of alopecia.

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    1. Cytokine-targeted treatment in alopecia areata - new possibilities? Prospects in Pharmaceutical Sciences · 2023 · 1 citations
    2. Innovative Therapeutic Strategies in TYK2-Targeted Treatments: From Cancer to Autoimmune Disorders ACS Medicinal Chemistry Letters · 2024 · 1 citations
    3. Cytokine Targeted Therapeutics for Alopecia Areata: Lessons from Atopic Dermatitis and Other Inflammatory Skin Diseases 2017 · 25 citations
    4. Dupilumab for alopecia areata treatment: A double‐edged sword? Journal of cosmetic dermatology · 2022 · 2 citations
    5. A retrospective review of paediatric alopecia areata cases seen in a tertiary institution in Singapore Singapore Medical Journal · 2022
    6. General Dermatology Springer eBooks · 2017
    7. Wounds and the Microbiota: The Healing Interplay Between Host and Microbial Communities International Journal of Molecular Sciences · 2025 · 2 citations
    8. Macrophages as central mediators of sympathetic neuro-immune interplay in autoimmunity Frontiers in Immunology · 2025
    9. Vitiligo: An Autoimmune Skin Disease and its Immunomodulatory Therapeutic Intervention Frontiers in Cell and Developmental Biology · 2021 · 61 citations
    10. A novel therapeutic paradigm for patients with extensive alopecia areata Expert Opinion on Biological Therapy · 2016 · 30 citations
    11. DataSheet2_Vitiligo: An Autoimmune Skin Disease and its Immunomodulatory Therapeutic Intervention.PDF OPAL (Open@LaTrobe) (La Trobe University) · 2021
    12. DataSheet1_Vitiligo: An Autoimmune Skin Disease and its Immunomodulatory Therapeutic Intervention.PDF Figshare · 2021
    13. 329 Mechanisms of Cutaneous Adverse Events during Targeted Cancer Therapy 2022
    14. Updated Treatment for Acne: Targeted Therapy Based on Pathogenesis Dermatology and Therapy · 2021 · 78 citations
    15. A Review on Nanoparticle Based Herbal Remedies for the Management of Alopecia Der Pharmacia Lettre · 2020
    16. Modern Therapies for Discoid Lupus Erythematosus: A Narrative Review Dermatology and Therapy · 2026
    17. New and Emerging Therapies for Alopecia Areata Drugs · 2020 · 46 citations
    18. The Changing Landscape of Alopecia Areata: The Therapeutic Paradigm Advances in Therapy · 2017 · 77 citations
    19. IMMUNOPATHOLOGY OF THE HUMAN HAIR FOLLICLE Dermatologic Clinics · 1999 · 15 citations
    20. 054 Deep Analysis of CD4+ Trm Cells in Normal and Atopic Dermatitis Human Skin Journal of Investigative Dermatology · 2025
    21. 455 Beyond Immunity: TEC and JAK3 Kinase Activation in Melanocytes Drives Inflammation in Vitiligo Journal of Investigative Dermatology · 2025
    22. New developments in our understanding of acne pathogenesis and treatment Experimental dermatology · 2009 · 466 citations
    23. Langerin+ Dendritic Cells in Cutaneous Fibrosis: The TGF-β1 Signaling Axis Clinical Cosmetic and Investigational Dermatology · 2025
    24. Comparative evaluation of cytokine profiles in pediatric alopecia areata patients considering concomitant atopic diseases: An observational cohort cross-sectional study Kuban Scientific Medical Bulletin · 2025
    25. Alopecia Areata: Pathogenesis, Diagnosis, and Therapies MedComm · 2025 · 21 citations
    26. Immunosenescence and inflammaging in Parkinson’s disease: mechanisms and therapeutic prospects Frontiers in Immunology · 2026
    27. Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases Cell · 2020 · 227 citations
    28. Hair follicles as immune targets: unraveling cellular players, cytokine crosstalk, and precision pathways for future therapy of alopecia areata Expert Review of Clinical Immunology · 2026
    29. Иммунологические аспекты гнездной алопеции: от патогенеза к терапевтическим стратегиям International journal of medicine and psychology. · 2024
    30. Detection of Serum Levels of Interleukins-17, 21, 6 and Tumor Necrosis Factor-α in Patients with Patchy Alopecia Areata and Their Association with Disease Severity Diseases · 2025