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The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The Rotterdam Study aims to understand various diseases in older adults.

Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Over one-third of women experience hair loss, with female-pattern hair loss being most common, and treatments include minoxidil and possibly hair transplantation.

Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.

Growth factors are crucial for hair development and could help treat hair diseases.

Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

Hair shedding is an active process that could be targeted to treat hair loss.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.

Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.

Finasteride improves hair density and thickness in women with hair loss.

Adults with polycystic ovary syndrome are much more likely to have obstructive sleep apnea.

Young Czech women with PCOS have a higher risk of heart problems and should be regularly checked for cholesterol and glucose issues.

Oxidative stress damages hair and contributes to aging, and managing it can help maintain hair health.

Both mouse and rat models are effective for testing alopecia areata treatments.

The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.