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The document concludes that inherited epidermolysis bullosa is a challenging genetic condition requiring multidisciplinary care and new treatments.

Tofacitinib shows promise for treating severe hair loss in adults and teens, with many experiencing regrowth, but hair loss returns when treatment stops.

Hedgehog signaling is crucial for mammary gland development over hair follicles.

Body hair transplantation is an effective method for restoring hair in people with severe baldness and limited scalp donor hair.

Older adults have a wide range of skin conditions, with dry skin being very common and many also experiencing skin growths, itching, and infections.

The document concludes that quick referral and appropriate treatments are crucial for managing common skin conditions and preventing permanent damage.

Oral minoxidil is a reasonably safe alternative for patients allergic to the topical form.

Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.

Using special RNA to target a mutant gene fixed hair problems in mice.

Stephen Rothman made important discoveries in dermatology, including the use of PABA in sunscreens, but never profited from his work.

Maintaining sexual health after menopause is possible with patient approaches, hormone supplements, and therapy, despite needing more research.

Acne in dark skin is influenced by environmental factors and can lead to hyperpigmentation, with various treatment options available.

Diagnosing Polycystic Ovary Syndrome is hard due to varying symptoms, no set criteria, and the need for better tests and education.

Early treatment of acne is crucial to prevent scarring and psychological effects.

PCOS has a strong genetic basis, but more research is needed to fully understand it.

Finasteride may improve sperm count in subfertile men with low sperm count.

Contact immunotherapy might help treat various skin conditions, but more research is needed to confirm its safety and effectiveness.

Gene therapy in mice increased lifespan and improved health without causing cancer.

The 18-year-old girl likely has a condition called müllerian agenesis, which caused her to not have a uterus and experience no menstrual periods.

A specific immune response helps control mite populations on the skin, maintaining healthy hair follicles.

The FDA warned about safety issues with remdesivir and tofacitinib, finasteride is linked to suicidality, potent topical corticosteroids increase osteoporosis risk, henna can cause hemolysis in G6PD deficiency, chemotherapeutic agents can cause adverse reactions, drug interactions are common in cancer patients, ketamine can reduce at-risk drinking, high dose of anticholinergics increases dementia risk in Parkinson's patients, and prenatal exposure to second-generation antipsychotics increases pregnancy complications.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

AMH helps estimate ovarian reserve but doesn't predict pregnancy chances; age is more important.

Premature graying of hair may suggest health issues and currently lacks effective treatments.

Female pattern hair loss diagnosed by scalp appearance, treated with combined therapies and targeted approaches.

Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.

Low-dose oral minoxidil safely treats hair loss, with hypertrichosis as main side effect.