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Diuretics can cause serious side effects and should be used carefully.

Topical 5-Fluorouracil can rarely cause nerve damage, especially in people with a certain genetic deficiency.

Systematic reviews on platelet-rich plasma therapy for hair loss have many quality issues.

Sodium valproate is effective in treating epilepsy, especially in patients who don't respond to other medications.

Trichotillomania is a chronic hair-pulling disorder, more common in females, treated with therapy and sometimes medication.

An 86-year-old man had a rare tongue melanoma but refused treatment, showing the need for early cancer detection and treatment.

Possible link between COVID-19 and hair loss; more research needed.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Pegylated liposomal doxorubicin is as effective as conventional doxorubicin but causes fewer heart problems and side effects.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Some wound-healing cells can turn into fat cells around new hair growth in mice.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Platelet-rich plasma can potentially promote hair growth by stimulating cell growth and increasing certain proteins.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Understanding where cancer cells come from helps create better prevention and treatment methods.

Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.