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    Glossary Cell Line

    population of cells grown and maintained in a lab

    A cell line is a population of cells that can be grown and maintained in a laboratory setting for extended periods. These cells are derived from a single cell and are genetically identical, allowing researchers to study biological processes, drug responses, and disease mechanisms in a controlled environment. Cell lines are crucial in medical research, including studies on hair growth and alopecia, as they provide a consistent and reproducible model for experimentation.

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    1. Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling Cell · 2011 · 499 citations
    2. Epithelial-Mesenchymal Micro-niches Govern Stem Cell Lineage Choices Cell · 2017 · 214 citations
    3. Establishment of keratinocyte cell lines from human hair follicles Scientific reports · 2018 · 16 citations
    4. A multi-omic single-cell landscape of perinatal mouse skin maps lineage specification and reveals shared dynamics in human fetal skin Experimental & Molecular Medicine · 2026
    5. DNMT1-mediated methylation inhibits microRNA-214-3p and promotes hair follicle stem cell differentiate into adipogenic lineages Stem cell research & therapy · 2020 · 8 citations
    6. Chemical Screening for Hair Cell Loss and Protection in the Zebrafish Lateral Line Zebrafish · 2010 · 114 citations
    7. Multi-potentiality of a new immortalized epithelial stem cell line derived from human hair follicles In vitro cellular & developmental biology. Animal · 2008 · 34 citations
    8. Establishment and characterization of an immortalized human dermal papilla cell line BMB Reports · 2011 · 21 citations
    9. Expression patterns of the glial cell line–derived neurotrophic factor, neurturin, their cognate receptors GFRα-1, GFRα-2, and a common signal transduction element c-Ret in the human skin hair follicles Journal of The American Academy of Dermatology · 2008 · 18 citations
    10. Stem cell identification-<i>in vivo</i> lineage analysis versus <i>in vitro</i> isolation and clonal expansion The Journal of Pathology · 2012 · 17 citations
    11. Single-cell transcriptomics reveals lineage trajectory of human scalp hair follicle and informs mechanisms of hair graying Cell discovery · 2022 · 13 citations
    12. Toward Elucidating Epigenetic and Metabolic Regulation of Stem Cell Lineage Plasticity in Skin Aging Frontiers in Cell and Developmental Biology · 2022 · 7 citations
    13. Establishment and Functional Characterization of Immortalized Rabbit Dermal Papilla Cell Lines Research Square (Research Square) · 2022
    14. Screening of Sheep Fibroblast Cell Line with the Spider Dragline Silk Protein Gene Xumu shouyi xuebao · 2009
    15. Metabolic pathway of Cis-UCA upon Ultraviolet B (UVB) exposure using ¹H Nuclear Magnetic Resonance (NMR) spectroscopy, Molecular Docking and cell viability of human keratinocytes (HaCaT) cell lines UiTM Institutional Repositories (Universiti Teknologi MARA) · 2026
    16. Multimodal Human Scalp Atlas Defines Cell Landscape and Lineage Architecture In Situ bioRxiv (Cold Spring Harbor Laboratory) · 2026
    17. Linear Basal Cell Carcinomas Dermatologic Surgery · 1999 · 3 citations
    18. Identification of the cell lineage at the origin of basal cell carcinoma Nature Cell Biology · 2010 · 351 citations
    19. Generation and characterization of rat liver stem cell lines and their engraftment in a rat model of liver failure Scientific Reports · 2016 · 48 citations
    20. Using the zebrafish lateral line to uncover novel mechanisms of action and prevention in drug-induced hair cell death Frontiers in Cellular Neuroscience · 2015 · 34 citations
    21. From Primary MSC Culture of Adipose Tissue to Immortalized Cell Line Producing Cytokines for Potential Use in Regenerative Medicine Therapy or Immunotherapy International Journal of Molecular Sciences · 2021 · 13 citations
    22. Induced pluripotent stem cell line MUSIi006-A derived from hair follicle keratinocytes as a non-invasive somatic cell source Stem cell research · 2018 · 7 citations
    23. Epidermal stem cell lineages Advances in stem cells and their niches · 2019 · 1 citations
    24. Generation of an integration-free human induced pluripotent stem cell line MUSIi010-A from occipital scalp fibroblasts of a male patient with androgenetic alopecia Stem Cell Research · 2019
    25. Human Skin is a Steroidogenic Tissue: Steroidogenic Enzymes and Cofactors Are Expressed in Epidermis, Normal Sebocytes, and an Immortalized Sebocyte Cell Line (SEB-1) Journal of Investigative Dermatology · 2003 · 289 citations
    26. Temporal Layering of Signaling Effectors Drives Chromatin Remodeling during Hair Follicle Stem Cell Lineage Progression Cell stem cell · 2018 · 85 citations
    27. Mechanisms and cell lineages in lymphatic vascular development Angiogenesis · 2021 · 43 citations
    28. ES Cell Differentiation Into the Hair Follicle Lineage In Vitro Humana Press eBooks · 2003 · 13 citations
    29. Genetic Tools for Cell Lineage Tracing and Profiling Developmental Trajectories in the Skin Journal of Investigative Dermatology · 2024 · 6 citations
    30. Targeted Knockout of β-Catenin in Adult Melanocyte Stem Cells Using a Mouse Line, Dct::CreERT2, Results in Disrupted Stem Cell Renewal and Pigmentation Defects Journal of Investigative Dermatology · 2020 · 3 citations