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Frontal fibrosing alopecia shows increased inflammation and JAK-STAT pathway activity without reduced hair proteins.

Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.

Scientists discovered a new way UVB light increases skin pigmentation through the ATP-P2X7 pathway.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Adenosine helps hair grow longer and stronger by boosting certain growth factors and signaling pathways.

Targeting TGFβ can improve skin immunity in older people.

The document concludes that MGRN1 affects mouse fur color by interfering with a receptor's signaling, but its full role in the body is still unknown.

Lipin-1 is important for skin cell differentiation and skin barrier function.

Finasteride blocks progesterone production in specific tumor cells, potentially causing side effects.

New cytokine-targeted therapies show promise for treating alopecia areata.

Too much androgen can cause hair loss; finasteride may help.

Bisphenol-A (BPA) increases connections between brain cells and boosts their activity, but it blocks the effects of a male hormone on brain cell plasticity.

Melatonin affects skin and hair color and protects skin cells, with potential benefits for hair growth and skin health.

Regulating cell death in hair follicles can help prevent hair loss and promote hair growth.

High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.

Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.

Some plants with flavonoids may help treat hair loss and promote hair growth.

Regenerative therapies show promise for treating vitiligo and alopecia areata.

Reducing 5α-reductase activity helps endometrial cells differentiate, aiding pregnancy.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.

The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.

Pulsatilla chinensis compounds may help prevent stress-related hair loss.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

The protein Gnαs is found more in black mice than white mice and may influence their coat color.

Fulvestrant at 10 mg/kg does not promote hair regrowth in dogs with alopecia X.

Hair color is determined by different melanins and changes with age.

PROTO1 and PROTO2 protect against hearing damage.

FOL-005, a hair growth promoter, acts locally on mouse skin where injected and could be a promising hair loss treatment.