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Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Platelet-rich plasma shows promise for skin and hair treatments but needs more research and standardization.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Fat tissue-derived cells show promise for repairing body tissues, but more research and regulation are needed for safe use.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Polysaccharides have many health benefits and are used in drugs, but isolating and purifying them is complex and requires careful methods.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Human skin can make serotonin and melatonin.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Stem cell niches support, regulate, and coordinate stem cell functions.

Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.

ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.