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120-150 / 1000+ resultsresearch Group Treatment for Trichotillomania: Behavior Therapy Versus Supportive Therapy
This study found that group behavior therapy for trichotillomania led to greater short-term symptom improvement compared to supportive therapy, but did not achieve clinically significant changes or prevent relapse over six months.
research A High Throughput LC-MS Platform for the Discovery of Autotaxin Inhibitors
In this study, researchers investigated the role of the ATX-LPA axis in asthma pathogenesis using human and mouse models and highlighted the potential for developing new ATX inhibitors as effective asthma treatments.
research Topical Application of Thermobalancing Therapy Enabled by Therapeutic Device Treats Enlarged Prostate and Improves Men's Quality of Life; New Opportunity in BPH Treatment
This abstract discusses treatment options for benign prostatic hyperplasia and provides no new clinical results.
research Biotinidase Deficiency: Prevalence, Impact And Management Strategies.
This review discusses biotinidase deficiency, noting that biotin treatment from birth can prevent symptoms, but acknowledges the complexity and need for further understanding due to late-onset cases with varied clinical findings.
research De novo designed bifunctional proteins for targeted protein degradation
This study demonstrated that de novo designed bifunctional proteins can target and degrade BCL-xL, leading to cell apoptosis, suggesting a new approach to targeted protein degradation therapy.
research Betamethasone actives cultured amelanotic melanocytes derived from outer root sheath of human hair follicle
This study found that betamethasone increased tyrosinase activity and melanin content in amelanotic melanocytes from human hair follicles, suggesting a potential mechanism for glucocorticoid treatment in vitiligo.
research The long road traveled in hematopoietic stem cell gene therapy
This study found that betibeglogene autotemcel significantly improved transfusion independence in 89% of patients with transfusion-dependent beta-thalassemia, although the high cost and manufacturing challenges may limit widespread adoption.
research Paxbp1 is Indispensable for the Maintenance of Hair Follicle Homeostasis
The Paxbp1 gene is crucial for healthy hair follicles.
research UTX (KDM6A) promotes differentiation noncatalytically in somatic self-renewing epithelia
In this study, researchers found that the histone demethylase UTX is crucial for regulating skin differentiation through retinoic acid signaling, mainly impacting females, as males compensate with a Y-linked paralog.
research Butyrophilin-like 2 (BTNL2) to the Rescue: controlling autoaggressive dermal gamma delta (GD) T lymphocytes in human hair follicles (HFs) 3747
This study observed that in human scalp hair follicles, BTNL2 expression is lower in stressed conditions, which correlates with increased cytotoxic activity by gamma/delta and CD8+ T cells, suggesting a possible role for BTNL2 in controlling immune responses relevant to alopecia areata.
research Androgenic Effects on Ventricular Repolarization
This study found that men receiving enzalutamide and other androgen-deprivation therapies may be at increased risk for QT prolongation and torsades de pointes.
research First-in-human phase 1 study of ETC-159 an oral PORCN inhbitor in patients with advanced solid tumours.
This phase I study reported that ETC-159, targeting Wnt signalling, showed tolerable safety profiles at doses that inhibit its pathway, though bone turnover markers increased, warranting early and regular monitoring. No tumor responses were observed, but two patients achieved stable disease for several cycles.
research Amelioration of trichotillomania with onabotulinumtoxinA for chronic migraine
This case report describes a woman with trichotillomania who experienced marked improvement and hair regrowth after off-label onabotulinumtoxinA treatment.
research Photosensitive Trichothiodystrophy with Complex Cerebral Abnormalities
This article reviews the genetic and phenotypic characteristics of Trichothiodystrophy and discusses the associated DNA repair defects, but does not report new clinical findings.
research Bullous mycosis fungoides with large cell transformation: a fatal outcome following brentuximab treatment
This study found that combining hair transplantation with platelet-rich plasma led to significantly better outcomes, such as reduced hair loss area and increased hair regeneration, compared to hair transplantation alone in patients with androgenic alopecia.
research Suppression of mammary tumorigenesis in transgenic mice by the RXR-selective retinoid, LGD1069.
This study found that the retinoid LGD1069 suppressed mammary tumorigenesis in a mouse model without observable toxicity, while TTNPB showed modest effects but was associated with significant toxicity.
research Recurrent MBTPS2 variant c.970+5G>A in IFAP syndrome: a mutational hotspot
In this study, researchers identified a recurrent MBTPS2 splice-site variant as a mutational hotspot in IFAP syndrome across diverse families, with phenotype severity suggesting the influence of additional modifiers.
research Bad Hair Restoration Result Repair Using BHT – FUE: Body Hair Transplantation
research Effect of the frequency of injection on the clinical responses of postmenopausal women to testosterone enanthate with estradiol valerate
This study found that a single 2 ml injection of TEEV every 4 weeks offers similar beneficial effects with fewer side effects compared to injecting the same dose every 2 weeks in postmenopausal women.
research Bicalutamide does not raise transaminases in comparison to alternative anti-androgen regimens among transfeminine adolescents and young adults: a retrospective cohort study
In this study, bicalutamide at low doses was not linked to significant liver enzyme changes compared to other androgen-blocking treatments in transfeminine adolescents and young adults, suggesting its safety with careful monitoring for this population over one year.
research Biotinidase deficiency characterized by skin and hair findings
This case report describes a girl in China with biotinidase deficiency confirmed by genetic mutations, whose skin and hair symptoms improved with biotin therapy.
research 42752 Evaluation of Eyebrow and Eyelash Regrowth and Patient Satisfaction in the Phase 3 THRIVE-AA1 Trial with CTP-543 (Deuruxolitinib) in Adult Patients with Moderate to Severe Alopecia Areata
CTP-543 significantly improved eyebrow and eyelash regrowth and patient satisfaction in adults with alopecia areata.
research Mechanisms and clinical progress of adipose-derived stem cells and their derivatives in the treatment of hair loss
This review examines adipose-derived stem cells as a promising therapy for alopecia but reports no new clinical results, discussing their potential mechanisms and the challenges faced in treatment development.
research Is Vibration Anesthesia Effective and Safe for Pain Reduction in Botulinum Toxin Injection? A Randomized Split-Face Controlled Trial and Cadaver Experiment
This study found that vibration anesthesia significantly reduced pain during botulinum toxin injections for masseter reduction without affecting the injection's diffusion or causing adverse effects, and high patient satisfaction was also reported.
research Novel Combination Scalp Therapy for Androgenetic Alopecia: A Preliminary Retrospective Case Series with an Illustrative Four-Year Case
This study reported that a single-session scalp procedure combining several components, including PRP and botulinum toxin, was associated with significant improvements in hair thickness and reduced vellus hair proportion in androgenetic alopecia patients, although further controlled trials are needed to establish causation.
research Cannabis sativa
This review covers the diverse applications of Cannabis sativa in areas like cancer treatment, skin care, and alopecia, but reports no new clinical results; continued research faces challenges due to legal variability.
research PTCH1 Germline Mutations and the Basaloid Follicular Hamartoma Values in the Tumor Spectrum of Basal Cell Carcinoma Syndrome (NBCCS)
This study suggests that NBCCS and BFHS may be the same genetic condition, which could help improve identification and management of misdiagnosed cases with specific surveillance strategies.
research Clinical Guidance on the Monitoring and Management of Trastuzumab Deruxtecan (T-DXd)-Related Adverse Events: Insights from an Asia-Pacific Multidisciplinary Panel
This source reports that trastuzumab deruxtecan improves outcomes in HER2-positive and HER2-low metastatic breast cancer, emphasizing the need for careful adverse event monitoring, particularly for interstitial lung disease, and managing emetic risk to maximize benefits.
research Case 4-2012
Early diagnosis and treatment of TPP can prevent complications.