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Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.

Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.

Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

The document concludes that gender-affirming treatments are essential for transgender individuals and outlines safe hormone therapy practices.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Finasteride may not affect gynecomastia recurrence after mastectomy.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

Balanced hormones are crucial for women's health, and can be managed with lifestyle changes or hormone therapy if needed.

Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.

SARMs may be an effective treatment for a certain type of breast cancer by blocking cancer growth and spread.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Rubbing vitamin D3 on skin can help prevent hair loss from chemotherapy and slow breast tumor growth in mice.

Breast cancer treatments work better with AR activation, improving results and reducing side effects.

Adding stem cells to fat grafts for facial rejuvenation might improve outcomes, but more research is needed to confirm safety and effectiveness.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Eclipta prostrata is a medicinal plant that helps treat diseases, protects the liver and nerves, and promotes hair growth.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Sugars from Sargassum and brown algae may have health benefits like fighting viruses and helping with wound healing, but there are challenges in using them.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

Minoxidil and ranolazine together can reduce the spread of certain breast cancer cells.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Low Vitamin D receptor levels in breast cancer are linked to worse outcomes and more bone metastases, and could be a marker for prognosis.

Reproductive hormones play a crucial role in breast cancer development and treatment challenges.