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The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Teriflunomide effectively reduces relapses and disability in MS and has a manageable safety profile.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Polycystic Ovary Syndrome is common but often undiagnosed, and early treatment is important to prevent health problems.

Certain hormone treatments can improve acne and related conditions in women.

Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.

The document suggests various treatments for PCOS, including medication for menstrual issues, insulin resistance, and excess hair, as well as fertility treatments, while highlighting the need for personalized care and lifestyle changes.

Combination therapy with oral contraceptives and spironolactone improves hair growth, menstrual issues, and acne in women with PCOS.

Early treatment of PCOS in teens is crucial to prevent long-term health issues like diabetes and heart disease.

Hormonal changes and conditions like polycystic ovarian syndrome are major causes of adult acne in women, with varying prevalence among different ethnicities.

Epidermal nevi are skin cell clusters linked to various syndromes.

The document concludes that non-binary individuals need compassionate support and recognition in healthcare, without being pathologized.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Different body areas in mice produce different hair types due to interactions between skin layers.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

Some people experienced temporary hair loss after hair transplant surgery but recovered fully within 10 months.

Researchers developed a reliable way to measure hormones in urine, showing that a baldness treatment doesn't change hormone levels.

Immune cells are essential for early hair and skin development and healing.

Diabetic patients often have ingrown nails due to obesity, high blood pressure, past injuries, bad nail trimming, nail fungus, weak foot pulse, and weak knee reflex.

Iron supplements may reverse premature graying in iron-deficient individuals; ingrown nails are common in diabetics with certain risk factors; topical finasteride may reduce scalp DHT as effectively as oral finasteride; monilethrix treatment is challenging but some medications can help.

Iron supplements may reverse premature hair graying caused by iron deficiency.

Finasteride solution helps treat hair loss.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.

The document describes various skin conditions, their features, and treatments but lacks detailed study size information.

Hutchinson-Gilford Progeria Syndrome is a rare genetic disorder caused by a specific gene mutation, characterized by aging symptoms and managed by monitoring heart health and using low-dose aspirin.

Irradiating the whole central nervous system can lead to over 50% of patients with cerebellar medulloblastoma surviving three years.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Radiation therapy with a higher dose for the brain improves survival in cerebellar medulloblastoma.