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    Did you mean Basal Keratinocytes?
    Glossary Basal Keratinocytes

    cells in the skin's lowest epidermal layer producing keratin

    Basal keratinocytes are the cells located in the lowest layer of the epidermis, which is the outermost layer of the skin. These cells are responsible for producing keratin, a protein that helps protect the skin and underlying tissues. They also play a crucial role in skin regeneration by continuously dividing and pushing older cells towards the surface, where they eventually shed.

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    1. Keratin 15 promotes a progenitor cell state in basal keratinocytes of skin epidermis The Journal of Cell Biology · 2025
    2. α-parvin is required for epidermal morphogenesis, hair follicle development and basal keratinocyte polarity PloS one · 2020 · 7 citations
    3. Physiological and retinoid-induced proliferations of epidermis basal keratinocytes are differently controlled EMBO journal · 2002 · 127 citations
    4. Keratin 15 promotes a progenitor cell state in basal keratinocytes of skin epidermis bioRxiv (Cold Spring Harbor Laboratory) · 2025
    5. Isolating subpopulations of human epidermal basal cells based on polyclonal serum against trypsin-resistant CSPG4 epitopes Experimental cell research · 2016 · 2 citations
    6. 566 DermaCult™ Keratinocyte Expansion Medium, a Serum- and BPE-free Medium Supporting Long-term Feeder-free Expansion of Primary Human Epidermal and Pluripotent Stem Cell-Derived Keratinocytes Journal of Investigative Dermatology · 2022
    7. CD99 Is Strongly Expressed in Basal Cells of the Normal Adult Epidermis and Some Subpopulations of Appendages: Comparison with Developing Fetal Skin Journal of pathology and translational medicine · 2016 · 8 citations
    8. A Mouse Model for Conditional Expression of Activated β-Catenin in Epidermal Keratinocytes Transgenic Research · 2024 · 1 citations
    9. Epidermal keratinocyte stem cells: their maintenance and regulation Seminars in cell biology · 1992 · 25 citations
    10. 1340 Basal keratinocytes exhibit age-related epigenetic and transcriptomic alterations resulting in an altered metabolic profile Journal of Investigative Dermatology · 2023
    11. Human Eccrine Sweat Gland Cells Can Reconstitute a Stratified Epidermis Journal of Investigative Dermatology · 2010 · 103 citations
    12. Bikunin, a Serine Protease Inhibitor, is Present on the Cell Boundary of Epidermis Journal of Investigative Dermatology · 1999 · 13 citations
    13. 707 Chromatin remodeler Lymphoid-specific helicase (Lsh) is a critical determinant controlling postnatal epidermal growth, differentiation and response to injury Journal of Investigative Dermatology · 2016
    14. Life before and beyond blistering: The role of collagen XVII in epidermal physiology Experimental Dermatology · 2018 · 63 citations
    15. Epidermal Stem Cells do not Communicate Through Gap Junctions Journal of Investigative Dermatology · 2002 · 73 citations
    16. Abnormal differentiation of epidermis in transgenic mice constitutively expressing cyclooxygenase-2 in skin Proceedings of the National Academy of Sciences · 2001 · 201 citations
    17. Characterization of the epidermal-dermal junction in hiPSC-derived skin organoids Stem cell reports · 2022 · 14 citations
    18. The Expression of Vitamin D-Upregulated Protein 1 in Skin and its Interaction with Sciellin in Cultured Keratinocytes 2003 · 18 citations
    19. A Niche Above: A Novel Modality of Stem Cell Regulation in Mammalian Skin Epidermis Cell stem cell · 2021
    20. 1337 Single cell transcriptome profiling of human interfollicular epidermis reveals robust heterogeneity and divergent differentiation lineages Journal of Investigative Dermatology · 2018
    21. A two-phase model of skin epidermal stratification: lessons from centrosomes bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 1 citations
    22. Keratin K15 as a Biomarker of Epidermal Stem Cells International Journal of Molecular Sciences · 2013 · 85 citations
    23. Activated Kras Alters Epidermal Homeostasis of Mouse Skin, Resulting in Redundant Skin and Defective Hair Cycling Journal of Investigative Dermatology · 2010 · 29 citations
    24. Nuclear Topology, Epigenetics, and Keratinocyte Differentiation Journal of Investigative Dermatology · 2013 · 2 citations
    25. Overexpression of activin A in the skin of transgenic mice reveals new activities of activin in epidermal morphogenesis, dermal fibrosis and wound repair EMBO journal · 1999 · 204 citations
    26. Hair follicle and interfollicular epidermal stem cells make varying contributions to wound regeneration Cell Cycle · 2015 · 47 citations
    27. Eph/ephrin signaling in epidermal differentiation and disease Seminars in Cell & Developmental Biology · 2011 · 42 citations
    28. Keratinocyte-Specific Onset of Serine Protease BSSP Expression in Experimental Carcinogenesis Journal of Investigative Dermatology · 2001 · 26 citations
    29. Thy1 marks a distinct population of slow-cycling stem cells in the mouse epidermis Nature communications · 2022 · 7 citations
    30. Epidermal Cells Expressing Putative Cell Markers in Nonglabrous Skin Existing in Direct Proximity with the Distal End of the Arrector Pili Muscle Stem Cells International · 2016 · 5 citations