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    Did you mean Aromatase Inhibitors?
    Glossary Aromatase Inhibitors

    block estrogen production by inhibiting the aromatase enzyme

    Aromatase Inhibitors (AIs) are a class of drugs that block the enzyme aromatase, which is responsible for converting androgens into estrogens. By reducing estrogen levels, AIs are commonly used in the treatment of hormone-receptor-positive breast cancer in postmenopausal women, as estrogen can promote the growth of certain types of breast cancer cells.

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    Research 30 of 1000+

    1. Management of Sexual Dysfunction in Postmenopausal Breast Cancer Patients Taking Adjuvant Aromatase Inhibitor Therapy Current Oncology · 2007 · 90 citations
    2. Reduced estradiol synthesis by letrozole, an aromatase inhibitor, is protective against development of pentylenetetrazole-induced kindling in mice Neurochemistry International · 2015 · 14 citations
    3. Aromatase inhibition by letrozole attenuates kainic acid-induced seizures but not neurotoxicity in mice Epilepsy research · 2018 · 11 citations
    4. Androgenic Efficacy and Mechanism of Glycosides-Based Standardized Fenugreek Seeds Extract Through Aromatase And 5-Alpha Reductase Inhibition Pharmacognosy Journal · 2024 · 1 citations
    5. Aromatase-independent testosterone conversion into estrogenic steroids is inhibited by a 5α-reductase inhibitor The Journal of Steroid Biochemistry and Molecular Biology · 2005 · 44 citations
    6. Aromatase inhibitor–induced hair loss in two adolescents Pediatric Dermatology · 2020 · 1 citations
    7. A case of aromatase inhibitor‐induced alopecia successfully treated with low‐dose oral minoxidil Journal of Cosmetic Dermatology · 2023
    8. The Aromatase Inhibitor Fadrozole and the 5-Reductase Inhibitor Finasteride Affect Gonadal Differentiation and Gene Expression in the Frog <i>Silurana tropicalis</i> Sexual Development · 2009 · 37 citations
    9. Aromatase inhibitor therapy and hair loss among breast cancer survivors Breast Cancer Research and Treatment · 2013 · 34 citations
    10. CDK4/6 plus aromatase inhibitor-induced alopecia in breast cancer patients. Journal of Clinical Oncology · 2019 · 4 citations
    11. SAT-288 Successful Virilization of a PAIS Patient with a Missense Mutation In The Ligand-binding Domain Of The Androgen Receptor with Combined High-dose Testosterone and Aromatase Inhibitor Journal of the Endocrine Society · 2019
    12. Amiodarone-Induced Toxic Epidermal Necrolysis; Nilotinib-Associated Cerebrovascular Disease and Stroke; Pisa Syndrome Caused by Paliperidone; Macroglossia Associated with Methylprednisolone; Aromatase Inhibitor-Induced “Male Pattern Baldness” in Women? Acute Liver Failure Due to Etodolac Hospital Pharmacy · 2013
    13. Increase in formalin-induced tonic pain by 5alpha-reductase and aromatase inhibition in female rats Pharmacology Biochemistry and Behavior · 2010 · 13 citations
    14. The Safety of Local Hormonal Treatment for Vulvovaginal Atrophy in Women With Estrogen Receptor-positive Breast Cancer Who Are on Adjuvant Aromatase Inhibitor Therapy: Meta-analysis Clinical breast cancer · 2019 · 18 citations
    15. NEONATAL INHIBITION OF ANDROGEN ACTIVITY ALTERS THE PROGRAMMING OF BODY WEIGHT AND OREXINERGIC PEPTIDES DIFFERENTIALLY IN MALE AND FEMALE RATS Brain research bulletin · 2024
    16. Effects of chronic inhibition of Testosterone metabolism on cardiac remodeling after ischemia/reperfusion-induced myocardial damage in gonadectomized rats Biology open · 2019 · 4 citations
    17. Testosterone modulation of seizure susceptibility is mediated by neurosteroids 3α-androstanediol and 17β-estradiol Neuroscience · 2004 · 136 citations
    18. The Current Status of the Pharmaceutical Potential of Juniperus L. Metabolites Medicines · 2018 · 19 citations
    19. Endocrine treatment of benign prostatichypertrophy: Current concepts Urology · 1991 · 11 citations
    20. A Comprehensive Review on Phytochemistry and Pharmacological Effects of Stinging Nettle (Urtica dioica) Current traditional medicine · 2017 · 8 citations
    21. Drug safety evaluation of exemestane Expert Opinion on Drug Safety · 2011 · 7 citations
    22. Early androgen activity after birth determines the hypothalamic expression of androgen and estrogen receptors in adulthood in female but not in male rats Reproductive Biology and Endocrinology · 2025
    23. SUN-118 A Case of Anastrozole Induced Hyperandrogenism Journal of the Endocrine Society · 2025
    24. Androgens and ovarian function: translation from basic discovery research to clinical impact Journal of Endocrinology · 2019 · 55 citations
    25. Cellular actions of testosterone in vascular cells: Mechanism independent of aromatization to estradiol Steroids · 2012 · 55 citations
    26. Real-World Safety Profile of Generic Palbociclib in Hormone Receptor–Positive, HER2-Negative Metastatic Breast Cancer: A Prospective Observational Study in Iraq” Journal of cancer research updates · 2026
    27. Formestane Preferred as Second-Line Therapy in Advanced Breast Cancer Drugs & Therapy Perspectives · 1993
    28. Update on polycystic ovary syndrome Clinical and Experimental Reproductive Medicine · 2021 · 4 citations
    29. Daily subcutaneous testosterone for management of testosterone deficiency Frontiers in bioscience · 2018 · 3 citations
    30. Bladder Cancer: The Hormonal Dependence Enigma and a New Hormonal Player Indian Journal of Surgery · 2014 · 3 citations