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    Glossary Apoptosis Regulator

    protein controlling programmed cell death in cells

    An apoptosis regulator, also known as a cell death regulator, is a protein that controls the process of apoptosis, which is the programmed death of cells. This process is crucial for maintaining healthy tissue by eliminating damaged or unnecessary cells. Dysregulation of apoptosis can lead to diseases such as cancer, where cells avoid death and proliferate uncontrollably, or degenerative diseases, where excessive cell death occurs.

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    1. Ginsenoside F2 Reduces Hair Loss by Controlling Apoptosis through the Sterol Regulatory Element-Binding Protein Cleavage Activating Protein and Transforming Growth Factor-β Pathways in a Dihydrotestosterone-Induced Mouse Model Biological & Pharmaceutical Bulletin · 2014 · 22 citations
    2. Evaluation of apoptosis regulatory markers in androgenetic alopecia Journal of Cosmetic Dermatology · 2010 · 6 citations
    3. Topical ALA-Photodynamic Therapy for Acne Can Induce Apoptosis of Sebocytes and Down-regulate Their TLR-2 and TLR-4 Expression Annals of Dermatology · 2011 · 37 citations
    4. 1272 p21Waf1/Cip1 is differentially expressed in epidermal versus follicular melanocytes and melanoma cells and is phenotypically regulated by UVB-mediated apoptosis 2023
    5. Regulatory T Cells in Autoimmune Diseases and their Potential Journal of Investigative Dermatology Symposium Proceedings · 2005 · 3 citations
    6. 496 Identification of differentially expressed miRNAs in alopecia areata that target immune-regulatory pathways 2017
    7. Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells Journal of immunology research · 2019 · 47 citations
    8. Apoptosis resistance in peripheral blood lymphocytes of alopecia areata patients Journal of Autoimmunity · 2004 · 38 citations
    9. Mutations in SREBF1, Encoding Sterol Regulatory Element Binding Transcription Factor 1, Cause Autosomal-Dominant IFAP Syndrome American journal of human genetics · 2020 · 34 citations
    10. Dermal PapillaCell-Derived Exosomes Regulate Hair Follicle Stem Cell Proliferation via LEF1 International Journal of Molecular Sciences · 2023
    11. Integrative analysis reveals ncRNA-mediated molecular regulatory network driving secondary hair follicle regression in cashmere goats BMC Genomics · 2018 · 50 citations
    12. The Lysosomal Protease Cathepsin L Is an Important Regulator of Keratinocyte and Melanocyte Differentiation During Hair Follicle Morphogenesis and Cycling ˜The œAmerican journal of pathology · 2002 · 146 citations
    13. <i>FGF20</i> Secreted From Dermal Papilla Cells Regulate the Proliferation and Differentiation of Hair Follicle Stem Cells in Fine‐Wool Sheep Journal of Animal Physiology and Animal Nutrition · 2024 · 3 citations
    14. Vasoactive Intestinal Peptide Operates as a Negative Regulator of Human Hair Follicle Pigmentation Ex Vivo Journal of Investigative Dermatology · 2024
    15. Decorin-mediated dermal papilla cell-derived exosomes regulate hair follicle growth and development through miR-129-2-3p/SMAD3/TGF-β axis International Journal of Biological Macromolecules · 2025
    16. Retinoic Acid-Related Orphan Receptor Alpha May Regulate the State of Hair Follicle Stem Cells by Upregulating the Expression of BNIP3 Animals · 2024
    17. lncRNA H19 acts as a ceRNA to regulate the expression of CTGF by targeting miR-19b in polycystic ovary syndrome Brazilian Journal of Medical and Biological Research · 2020 · 21 citations
    18. lncRNA2919 Suppresses Rabbit Dermal Papilla Cell Proliferation via trans-Regulatory Actions Cells · 2022 · 4 citations
    19. The Circular RNA CircCOL1A1 Functions as a miR-149-5p Sponge to Regulate the Formation of Superior-Quality Brush Hair via the CMTM3/AR Axis Frontiers in cell and developmental biology · 2022 · 3 citations
    20. Involvement of Activation of Mitogen-Activated Protein Kinase (MAPK)/Extracellular Signal-Regulated Kinase (ERK) Signaling Pathway in Proliferation of Urethral Plate Fibroblasts in Finasteride-Induced Rat Hypospadias Medical Science Monitor · 2018 · 10 citations
    21. Differential effects of melatonin as a broad range UV-damage preventive dermato-endocrine regulator Dermato-endocrinology · 2011 · 31 citations
    22. Wnt/β‐catenin and ERK pathway activation: A possible mechanism of photobiomodulation therapy with light‐emitting diodes that regulate the proliferation of human outer root sheath cells Lasers in Surgery and Medicine · 2017 · 43 citations
    23. Laminin-511, inducer of hair growth, is down-regulated and its suppressor in hair growth, laminin-332 up-regulated in chemotherapy-induced alopecia Journal of dermatological science · 2010 · 13 citations
    24. 1432 IL-9/IL-9R signaling as a novel regulator of human hair follicle growth and immune privilege Journal of Investigative Dermatology · 2023
    25. Phosphatidic Acid Has a Potential to Promote Hair Growth In Vitro and In Vivo, and Activates Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase in Hair Epithelial Cells 2003 · 46 citations
    26. A genomic approach to susceptibility and pathogenesis leads to identifying potential novel therapeutic targets in androgenetic alopecia Genomics · 2017 · 13 citations
    27. Post-transcriptional Regulation of Keratinocyte Progenitor Cell Expansion, Differentiation and Hair Follicle Regression by miR-22 PLOS Genetics · 2015 · 52 citations
    28. Hair Loss Caused by Gain-of-Function Mutant TRPV3 Is Associated with Premature Differentiation of Follicular Keratinocytes 2021 · 11 citations
    29. Le gène<i>hairless</i>de la souris 2006 · 4 citations
    30. A systematic summary of survival and death signalling during the life of hair follicle stem cells Stem Cell Research & Therapy · 2021 · 31 citations