In this study, nearly 38% of Saudi women with PCOS reported extremely severe depression and extreme anxiety, with higher rates linked to young age, divorce, lifestyle advice, and higher BMI.
December 2023 in “Alzheimer's & dementia” In this rodent study, researchers found that the drug finasteride may reduce anxiety and depression-like behaviors in a model of aging, despite inducing metabolic disturbances and depressive-like behaviors in young rats, suggesting potential considerations for its use in elderly populations.
January 2016 in “International Journal of Medical Research and Health Sciences” This study found that trichodynia was significantly more common in patients with Telogen Effluvium and Alopecia Areata, and anxiety frequently accompanied trichodynia in these conditions.
May 2026 in “Journal of Clinical Medicine” This meta-analysis found a significantly higher prevalence of depressive symptoms in women with PCOS compared to a control group, with 42.11% versus 13.62% according to the BDI assessment, highlighting the need for psychiatric evaluation and support for women with this syndrome.
November 2025 in “Anxiety Stress & Coping” This study found that generalized anxiety disorder symptoms predicted higher emotional distress and hair cortisol concentration, with dominance unexpectedly increasing the impact of anxiety on hair cortisol.
May 2025 in “Psychopharmacology” In this study, chronic finasteride administration in male rats led to depression- and anxiety-like behaviors only in specific tests and moderately affected hippocampal synaptic plasticity, possibly due to adaptive plasma corticosterone level changes over time.
April 2024 in “Journal of psychiatric research” This study observed that short-term administration of finasteride in male Wistar rats induced anxiety-like and depression-like behaviors, impaired spatial learning and memory, and reduced synaptic plasticity in the hippocampus, with a trend of increased corticosterone levels noted.
September 2023 in “Khyber Medical University Journal” This study found that 52.4% of alopecia patients in Karachi experienced abnormal levels of anxiety, 53.6% had depression, and 48.8% reported low self-esteem, emphasizing a need for psychological interventions in this population.
August 2020 in “The American Journal of Cosmetic Surgery” This study found that hair transplant surgery significantly reduced anxiety scores in bald patients over an average period of 12.7 months.
January 2016 in “Medicinski Podmladak” This study found that finasteride led to increased anxiety-like behavior related to bright spaces in rats, but did not significantly affect open space anxiety-like behavior.
49 citations
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September 2016 in “Genes Brain & Behavior” In this study, a deficiency in the zinc finger protein Zfp462 in mice led to anxiety-like behaviors and excessive self-grooming, providing a new model for studying anxiety disorders.
29 citations
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November 2018 in “Journal of The European Academy of Dermatology and Venereology” This study found that anxiety-related traits significantly predict the impact of hair loss on quality of life across different alopecia types, with variations observed based on gender.
16 citations
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August 2022 in “Frontiers in Psychiatry” This study found that Chinese participants experiencing anxiety were significantly more likely to worry about the sequelae of Omicron compared to peers in North America and Western Europe.
12 citations
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February 2017 in “International journal of developmental neuroscience” This study observed that reduced in utero exposure to the neurosteroid allopregnanolone increased anxiety-like behavior in female guinea pigs during the juvenile period without affecting long-term allopregnanolone levels.
10 citations
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January 2012 in “International Journal of Trichology” This study found no significant association between serum levels of vitamin B12, folate, TSH, ferritin, zinc, or anxiety scores and trichodynia in telogen alopecia patients.
3 citations
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October 2024 in “Journal of obstetrics and gynaecology research” Postpartum hair loss can increase anxiety in new mothers.
March 2026 in “Healthcare” In this study conducted among adult dermatology clinic attendees in Saudi Arabia, laser hair removal-related anxiety was generally low, but misconceptions were common; increased knowledge was linked to reduced anxiety, suggesting educational interventions could improve informed decision-making.
September 2025 in “Cyprus Journal of Medical Sciences” In this study, patients with acute alopecia areata experienced significantly higher anxiety and depression levels, along with a worsened quality of life, compared to a control group, underscoring the importance for clinicians to address these psychiatric issues early in the condition.
August 2025 in “Libyan Medical Journal” This study found that patients with vitiligo or alopecia areata have higher levels of anxiety and depression compared to healthy individuals, though no significant differences were observed between the two patient groups, highlighting the psychological impact of these dermatological conditions.
August 2025 in “European Journal of Dermatology” This study found that patients with telogen effluvium experienced higher stress, depression, anxiety, and lower quality of life compared to healthy controls.
June 2024 in “British Journal of Dermatology” This study reported that while both DLQI and HADS showed moderate correlations, only DLQI correlated with clinician-assessed disease severity in patients with alopecia.
February 2024 in “Psychoneuroendocrinology” This study observed that higher anxiety levels in pregnant individuals are negatively correlated with neonatal hair cortisol, suggesting that increased anxiety during pregnancy may affect fetal cortisol accumulation, which is important for fetal development and associated with birth outcomes and cognitive function.
February 2024 in “Psychoneuroendocrinology” In this study, researchers found that higher levels of general and pregnancy-related anxiety during gestation were negatively correlated with neonatal hair cortisol levels, suggesting that increased maternal anxiety may alter fetal cortisol exposure, which is important for fetal development.
November 2023 in “JEADV Clinical Practice” In this study, adults with severe alopecia areata experienced greater improvements in hair regrowth, health-related quality of life, and reduced anxiety and depression symptoms after 36 weeks of treatment with baricitinib compared to placebo.
April 2023 in “Journal of Investigative Dermatology” This study found that short-term NB-UVB treatment significantly reduced anxiety levels in psoriasis patients, but not depression.
January 2023 in “Siriraj Medical Journal” This study found that listening to music can effectively reduce preoperative anxiety in patients undergoing hair transplantation.
January 2018 in “Turkiye Klinikleri Journal of Medical Sciences” This study observed that while alopecia treatment in patients showed some improvements in quality of life and anxiety scores at six months, these changes were not statistically significant.
January 2023 in “Dermatologic Therapy” This study demonstrates a significant correlation between anxiety, depression, and reduced quality of life in individuals with androgenetic alopecia.
55 citations
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March 2005 in “Neuropharmacology” A neurosteroid can reduce caffeine-induced anxiety in rats.
27 citations
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April 2008 in “Neuroscience Letters” Olanzapine reduces stress-related anxiety in rats when given acutely.