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The hydrogel with 20% Hibiscus rosa-sinensis extract was the best for potential therapeutic use.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

Finasteride doesn't effectively treat hair loss in postmenopausal women.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.

Androgens can both increase and decrease hair growth in different parts of the body.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Modern science supports the use of some Ayurvedic plants for health, as ancient practices suggested.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

PCOS is a common hormonal disorder in women, marked by symptoms like hair growth and menstrual issues, and requires personalized treatment.

Some drugs can cause hair loss, change hair color and shape, or increase hair growth, and treatment may involve stopping the drug or using specific hair growth treatments.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Low-dose gonadotropin treatment is effective for infertility in women with PCOS, leading to high ovulation rates and comparable pregnancy rates with fewer complications.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Low-dose finasteride may cause lasting sexual dysfunction and suicidal thoughts in young men.

Some breast cancer chemotherapy can cause permanent hair loss.

Fulvestrant is a well-tolerated new treatment for advanced breast cancer that may delay chemotherapy.