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    Glossary Androgen Receptor Gene

    encodes a protein that binds male hormones like testosterone

    The Androgen Receptor Gene (AR Gene) is a gene located on the X chromosome that encodes the androgen receptor, a protein that binds to androgens, which are male hormones like testosterone. This receptor plays a crucial role in the development and maintenance of male characteristics, and mutations in the AR gene can lead to conditions such as androgen insensitivity syndrome and contribute to hair loss disorders like androgenetic alopecia.

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    Research 30 of 1000+

    1. Novel Androgen Receptor Gene Variant Containing a Premature Termination Codon in a Patient with Androgen Insensitivity Syndrome Journal of pediatric & adolescent gynecology · 2019 · 1 citations
    2. Evidence for two independent functional variants for androgenetic alopecia around the androgen receptor gene Experimental Dermatology · 2010 · 26 citations
    3. A variant of the glucocorticoid receptor gene is not associated with adrenal androgen excess in women with polycystic ovary syndrome Fertility and Sterility · 2000 · 20 citations
    4. Androgen receptor genetic variant predicts COVID‐19 disease severity: a prospective longitudinal study of hospitalized COVID‐19 male patients Journal of the European Academy of Dermatology and Venereology · 2020 · 26 citations
    5. The Glucocorticoid Resistance Syndrome. Two Cases of a Novel Pathogenic Variant in the Glucocorticoid Receptor Gene JCEM case reports · 2023
    6. Susceptibility variants on chromosome 7p21.1 suggest HDAC9 as a new candidate gene for male-pattern baldness British Journal of Dermatology · 2011 · 51 citations
    7. THERAPEUTIC HOTLINE: Genetic variations in the androgen receptor gene and finasteride response in women with androgenetic alopecia mediated by epigenetics Dermatologic Therapy · 2011 · 16 citations
    8. Polymorphisms of the Androgen Receptor Gene and the Estrogen Receptor β Gene Are Associated with Androgen Levels in Women1 The Journal of Clinical Endocrinology and Metabolism · 2001 · 93 citations
    9. Genetic analysis of the role of androgen metabolism in the pathogenesis of prostate cancer SUNScholar (Stellenbosch University) · 2004
    10. Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia American Journal of Human Genetics · 2005 · 195 citations
    11. Lack of concordance and linkage disequilibrium among brothers for androgenetic alopecia and CAG/GGC haplotypes of the androgen receptor gene in Mexican families Journal of Cosmetic Dermatology · 2015 · 2 citations
    12. Polymorphism of the Androgen Receptor Gene is Associated with Male Pattern Baldness Journal of Investigative Dermatology · 2001 · 299 citations
    13. Relationship between betacoronaviruses and the endocrine system: a new key to understand the COVID-19 pandemic—A comprehensive review Journal of Endocrinological Investigation · 2021 · 23 citations
    14. An interview Drs. Felix Brockschmidt and Markus Nöthen about the genetics of androgenetic alopecia Hair transplant forum international · 2009
    15. Immunological aspects and gender bias during respiratory viral infections including novel Coronavirus disease‐19 (COVID‐19): A scoping review Journal of Medical Virology · 2021 · 11 citations
    16. Insights into Male Androgenetic Alopecia: Differential Gene Expression Profiling of Plucked Hair Follicles and Integration with Genetic Data Journal of Investigative Dermatology · 2018 · 7 citations
    17. Androgen Receptor Polymorphism-Dependent Variation in Prostate-Specific Antigen Concentrations of European Men Cancer Epidemiology, Biomarkers & Prevention · 2014 · 9 citations
    18. Recent positive selection of a human androgen receptor/ectodysplasin A2 receptor haplotype and its relationship to male pattern baldness Human Genetics · 2009 · 42 citations
    19. Genetic and hormonal influence on SARS-CoV-2-infection susceptibility Annals of Oncology · 2020 · 2 citations
    20. Male-pattern baldness susceptibility locus at 20p11 Nature Genetics · 2008 · 111 citations
    21. Sex differences in COVID-19: the role of androgens in disease severity and progression Endocrine · 2020 · 121 citations
    22. DEFINING THE ROLE OF ABI1 GENE IN PROSTATE CANCER PROGRESSION AND TREATMENT RESISTANCE Wiadomości Lekarskie · 2024
    23. Perspectives of Kennedy's disease Journal of the Neurological Sciences · 2010 · 65 citations
    24. Social selection favours offspring prone to the development of androgenetic alopecia. PubMed · 2018
    25. Genetic basis of polycystic ovary syndrome Expert Review of Endocrinology & Metabolism · 2010 · 18 citations
    26. Genomic Markers and Personalized Medicine in Androgenetic Alopecia: A Comprehensive Review Cosmetics · 2024
    27. Sexual steroid regulation of spermatogenesis: new actors enter the stage Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) · 2011
    28. Antiandrogenic activity of Riboflavin 5′-phosphate (FMN) in 22Rv1 and LNCaP human prostate cancer cell lines European Journal of Pharmacology · 2022 · 1 citations
    29. Androgen receptor gene polymorphism and polycystic ovary syndrome 2012 · 45 citations
    30. No Evidence that 2D:4D is Related to the Number of CAG Repeats in the Androgen Receptor Gene Frontiers in Endocrinology · 2013 · 40 citations