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    Did you mean Androgen Receptor Antagonists?
    Glossary Androgen Receptor Antagonists

    block male hormones like testosterone from affecting tissues

    Androgen Receptor Antagonists, also known as antiandrogens, are medications that block the action of androgens, which are male sex hormones like testosterone. These drugs work by binding to androgen receptors, preventing androgens from exerting their effects on tissues, and are commonly used in the treatment of conditions like prostate cancer, androgenic alopecia (male-pattern baldness), and certain types of acne.

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    1. Cross-species sensitivity to a novel androgen receptor agonist of potential environmental concern, spironolactone Environmental Toxicology and Chemistry · 2013 · 25 citations
    2. Androgen Receptor Ligands: Agonists and Antagonists Elsevier eBooks · 2017 · 2 citations
    3. Three-Month Treatment With a Long-Acting Gonadotropin-Releasing Hormone Agonist of Patients With Benign Prostatic Hyperplasia: Effects on Tissue Androgen Concentration, 5<i>α</i>-Reductase Activity and Androgen Receptor Content* 1989 · 82 citations
    4. Recent discoveries and developments of androgen receptor based therapy for prostate cancer MedChemComm · 2015 · 17 citations
    5. Vitamin D and androgen receptor-targeted therapy for triple-negative breast cancer Breast Cancer Research and Treatment · 2016 · 59 citations
    6. Androgen receptor modulators: a review of recent patents and reports (2012-2018) Expert Opinion on Therapeutic Patents · 2019 · 23 citations
    7. Identification of Anabolic Selective Androgen Receptor Modulators with Reduced Activities in Reproductive Tissues and Sebaceous Glands 2009 · 36 citations
    8. Therapeutic Strategies to Target the Androgen Receptor Journal of Medicinal Chemistry · 2022 · 36 citations
    9. Glucagon-Like Peptide-1 Receptor Agonists and Hair Loss: Current Evidence and Potential Mechanisms JAAD reviews. · 2026
    10. Minoxidil May be a Partial Agonist of Estrogen Receptor Alpha microPublication · 2026
    11. Discovery of Nonsteroidal Androgens Biochemical and biophysical research communications · 1998 · 209 citations
    12. Chapter 23. Therapeutic Control of Androgen Action Annual Reports in Medicinal Chemistry · 1994 · 7 citations
    13. Design, Synthesis, and Biological Characterization of Metabolically Stable Selective Androgen Receptor Modulators Journal of medicinal chemistry · 2004 · 129 citations
    14. The Transcriptional Co-Activator cAMP Response Element-Binding Protein-Binding Protein Is Expressed in Prostate Cancer and Enhances Androgen- and Anti-Androgen-Induced Androgen Receptor Function American Journal of Pathology · 2003 · 72 citations
    15. Abiraterone and spironolactone in prostate cancer: a combination to avoid Acta Clinica Belgica · 2018 · 9 citations
    16. 25 years of ERβ: a personal journey Journal of molecular endocrinology · 2021 · 11 citations
    17. Гормональный дисбаланс как фактор развития хронического простатита: механизмы и перспективы терапии Репродуктивное здоровье Восточная Европа · 2025
    18. The efficacy of an adjuvant norethisterone (jenapharm) therapy in endometrial cancer 1987
    19. Hormone therapy in acne Indian Journal of Dermatology, Venereology and Leprology · 2013 · 24 citations
    20. Pharmacological Options for Treatment of Hyperandrogenic Disorders Mini-reviews in Medicinal Chemistry · 2009 · 6 citations
    21. Steroid Hormones Elsevier eBooks · 2016 · 3 citations
    22. Hormonal treatment of acne vulgaris: an update Clinical, Cosmetic and Investigational Dermatology · 2016 · 46 citations
    23. Characteristics of flutamide action on prostatic and testicular functions in the rat Journal of Steroid Biochemistry · 1988 · 30 citations
    24. Hormonal therapies for acne Clinics in Dermatology · 2016 · 26 citations
    25. Management of Hirsutism and Acne in Women with Polycystic Ovary Syndrome: A Narrative Review of Current Evidence and Emerging Therapies Quality in Sport · 2026
    26. Emerging pharmacotherapies for Androgenetic Alopecia Expert Opinion on Pharmacotherapy · 2026
    27. Androgens in female pig reproduction: actions mediated by the androgen receptor Bioscientifica Proceedings · 2019
    28. Nonsteroidal Selective Androgen Receptors Modulators (SARMs): Designer Androgens with Flexible Structures Provide Clinical Promise Endocrinology · 2004 · 28 citations
    29. Therapeutic Androgen Receptor Ligands Nuclear Receptor Signaling · 2003 · 16 citations
    30. Ornithine decarboxylase is upregulated by the androgen receptor in skeletal muscle and regulates myoblast proliferation AJP Endocrinology and Metabolism · 2011 · 43 citations