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    Glossary Androgen Production

    process of creating male sex hormones like testosterone

    Androgen production, also known as androgen synthesis, refers to the process by which the body produces androgens, a group of hormones that play a key role in male traits and reproductive activity. These hormones, including testosterone, are primarily produced in the testes in men and in smaller amounts in the ovaries and adrenal glands in women. Androgens are crucial for the development of male characteristics such as facial hair and a deeper voice, and they also influence muscle mass and libido.

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    1. AN ATTEMPT TO ASSESS THE MAGNITUDE OF ENDOGENOUS ANDROGEN PRODUCTION IN A CASE OF THE ADRENOGENITAL SYNDROME* The Journal of Clinical Endocrinology & Metabolism · 1952 · 9 citations
    2. The influence of non-esterified fatty acids (NEFA) on the ovarian production of androgens in a context of in vitro fertilisation (IVF) – preliminary results Fertility and Sterility · 2013
    3. Regional difference in sebum production by androgen susceptibility in human facial skin Experimental Dermatology · 2013 · 14 citations
    4. Synthesis and biological evaluation of amino-pyridines as androgen receptor antagonists for stimulating hair growth and reducing sebum production Bioorganic & Medicinal Chemistry Letters · 2007 · 17 citations
    5. (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile, a potent androgen receptor antagonist for stimulating hair growth and reducing sebum production Bioorganic & Medicinal Chemistry Letters · 2007 · 14 citations
    6. Rational Design of a Topical Androgen Receptor Antagonist for the Suppression of Sebum Production with Properties Suitable for Follicular Delivery Journal of Medicinal Chemistry · 2010 · 11 citations
    7. 4-(Alkylthio)- and 4-(arylthio)-benzonitrile derivatives as androgen receptor antagonists for the topical suppression of sebum production Bioorganic & Medicinal Chemistry Letters · 2009 · 11 citations
    8. Preparation of 4-aryl-2-trifluoromethylbenzonitrile derivatives as androgen receptor antagonists for topical suppression of sebum production Bioorganic & Medicinal Chemistry Letters · 2007 · 11 citations
    9. Diphenyl ethers as androgen receptor antagonists for the topical suppression of sebum production Bioorganic & Medicinal Chemistry Letters · 2009 · 7 citations
    10. Pantolactams as androgen receptor antagonists for the topical suppression of sebum production Bioorganic & Medicinal Chemistry Letters · 2011 · 5 citations
    11. In Silico Prediction of Metabolite in Petroselinum Crispum in Inhibiting Androgen Receptor as Treatment for Alopecia Research journal of pharmacy and technology · 2022 · 3 citations
    12. Androgens modulate keratinocyte differentiation indirectly through enhancing growth factor production from dermal fibroblasts Journal of dermatological science · 2019 · 20 citations
    13. 854 Dermal fibroblasts enhance growth factors production by androgens, and modulate keratinocyte proliferation and differentiation 2018
    14. 46,XY DSD due to impaired androgen production 2010 · 54 citations
    15. In vivo and in vitro exposure to free fatty acids induce increased androgen production in animal models: a potential pathogenic factor of the polycystic ovary syndrome Fertility and Sterility · 2008
    16. High-throughput and direct measurement of androgen levels using turbulent flow chromatography liquid chromatography-triple quadrupole mass spectrometry (TFC-LC-TQMS) to discover chemicals that modulate dihydrotestosterone production in human prostate cancer cells Biotechnology Letters · 2017 · 2 citations
    17. FINASTERIDE INHIBITS 5?-REDUCTASE ACTIVITY IN HUMAN DERMAL FIBROBLASTS: PREDICTION OF ITS THERAPEUTIC APPLICATION IN ANDROGEN-RELATED SKIN DISEASES International Journal of Dermatology · 1995 · 3 citations
    18. Intracrine androgen biosynthesis, metabolism and action revisited Molecular and Cellular Endocrinology · 2017 · 131 citations
    19. Androgen metabolism in hirsute patients treated with cyproterone acetate 1984 · 64 citations
    20. Defects in Androgen Biosynthesis Causing 46,XY Disorders of Sexual Development Seminars in reproductive medicine · 2012 · 46 citations
    21. Androgen treatment of postmenopausal women The Journal of Steroid Biochemistry and Molecular Biology · 2013 · 28 citations
    22. Androgen physiology and the cutaneous pilosebaceous unit. PubMed · 2001 · 21 citations
    23. Targets to treat androgen excess in polycystic ovary syndrome Expert Opinion on Therapeutic Targets · 2015 · 14 citations
    24. Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases Current Medicinal Chemistry · 2016 · 11 citations
    25. Androgens/Androgen Receptor in the Management of Skin Diseases Journal of Biosciences and Medicines · 2022 · 1 citations
    26. Androgen excess: a hallmark of polycystic ovary syndrome Frontiers in endocrinology · 2023
    27. Androgen Biosynthesis and Gene Defects Elsevier eBooks · 2014
    28. Advances in mitochondria-centered mechanism behind the roles of androgens and androgen receptor in the regulation of glucose and lipid metabolism Frontiers in endocrinology · 2023
    29. Gender Differences in Production and Circulating Levels of Sex Hormones and Their Impact on Aging Skin Springer eBooks · 2014
    30. Androgens and androgen receptor action in skin and hair follicles Molecular and Cellular Endocrinology · 2017 · 100 citations