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    Glossary Adrenocorticotropic Hormone

    hormone stimulating adrenal glands to release cortisol

    Adrenocorticotropic Hormone (ACTH), also known as corticotropin, is a hormone produced by the pituitary gland that stimulates the adrenal glands to release cortisol, a crucial stress hormone. This hormone plays a key role in regulating metabolism, immune response, and stress, and its imbalance can lead to conditions such as Cushing's disease or Addison's disease.

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    Research 30 of 634

    1. EFFECTS OF ADRENOCORTICOTROPIC HORMONE ON BODY GROWTH, VISCERAL PROPORTIONS, AND WHITE BLOOD CELL COUNTS OF NORMAL AND HYPOPHYSECTOMIZED MALE RATS Endocrinology · 1951 · 24 citations
    2. Adrenocorticotropic Hormone (ACTH) But Not Alpha-Melanocyte Stimulating Hormone (a-MSH) as a Mediator of Adrenalectomy Induced Hair Growth in Mink Journal of Investigative Dermatology · 1998 · 16 citations
    3. Idiopathic isolated adrenocorticotropic hormone deficiency combined with testicular germ cell tumor: Case report Medicine · 2025
    4. The human skin as a hormone target and an endocrine gland Hormones · 2004 · 146 citations
    5. Detection of Functionally Active Melanocortin Receptors and Evidence for an Immunoregulatory Activity of α-Melanocyte-Stimulating Hormone in Human Dermal Papilla Cells Endocrinology · 2005 · 60 citations
    6. Hormonal trends in patients suffering from long COVID symptoms Endocrine journal · 2022 · 25 citations
    7. The Hormonal Background of Hair Loss in Non-Scarring Alopecias Biomedicines · 2024
    8. Growth hormone deficiency with late-onset hypothalamic hypoadrenocorticism associated with respiratory and renal dysfunction: a case report BMC endocrine disorders · 2020
    9. The effect of hormones of the hypothalamic-pituitary-target gland axes in a kidney-yang deficiency syndrome model World Journal of Traditional Chinese Medicine · 2020 · 11 citations
    10. Human hair follicles display a functional equivalent of the hypothalamic‐pituitary‐adrenal (HPA) axis and synthesize cortisol The FASEB Journal · 2005 · 489 citations
    11. Female Pseudohermaphroditism Caused by a Novel Homozygous Missense Mutation of the GR Gene 2002 · 94 citations
    12. The Skin POMC System (SPS): Leads and Lessons from the Hair Follicle Annals of the New York Academy of Sciences · 1999 · 66 citations
    13. A neuroendocrinological perspective on human hair follicle pigmentation Pigment Cell & Melanoma Research · 2010 · 56 citations
    14. Central 5-alpha reduction of testosterone is required for testosterone's inhibition of the hypothalamo-pituitary–adrenal axis response to restraint stress in adult male rats Brain Research · 2013 · 51 citations
    15. Spatiotemporal Expression, Distribution, and Processing of POMC and POMC-derived Peptides in Murine Skin Journal of Histochemistry & Cytochemistry · 2000 · 49 citations
    16. Neuroimmunoregulation of Androgens in the Adrenal Gland and the Skin Hormone Research in Paediatrics · 2000 · 48 citations
    17. THE FUNCTIONAL INTERRELATIONSHIP OF THE ANTERIOR PITUITARY AND THE ADRENAL CORTEX Annals of Internal Medicine · 1951 · 41 citations
    18. Pituitary-dependent hyperadrenocorticism in a cat Journal of the American Veterinary Medical Association · 1986 · 29 citations
    19. HPA axis stress reactivity and hair cortisol concentrations in recently detoxified alcoholics and healthy controls with and without childhood maltreatment Addiction Biology · 2018 · 24 citations
    20. Melanocortin receptor type 2 (MC2R, ACTH receptor) expression in patients with alopecia areata Experimental Dermatology · 2010 · 22 citations
    21. The Steroidogenesis Inhibitor Finasteride Reduces the Response to Both Stressful and Rewarding Stimuli Biomolecules · 2019 · 20 citations
    22. Is it getting in the hair? – Cortisol concentrations in native, regrown and segmented hairs of cattle and pigs after repeated ACTH administrations General and comparative endocrinology · 2020 · 19 citations
    23. Adrenal 21-hydroxylase gene mutations in Slovenian hyperandrogenic women: evaluation of corticotrophin stimulation and HLA polymorphisms in screening for carrier status European journal of endocrinology · 1999 · 19 citations
    24. Development of Autoimmune Hair Loss Disease Alopecia Areata Is Associated with Cardiac Dysfunction in C3H/HeJ Mice PLOS ONE · 2013 · 18 citations
    25. ACTH as first line treatment for acute calcium pyrophosphate crystal arthritis in 14 hospitalized patients Joint Bone Spine · 2013 · 14 citations
    26. Severe and Fatal Phenobarbitone Eruptions The BMJ · 1952 · 14 citations
    27. The local hypothalamic–pituitary–adrenal axis in cultured human dermal papilla cells BMC Molecular and Cell Biology · 2020 · 9 citations
    28. CYP21A2 Mutations in Women with Polycystic Ovary Syndrome (PCOS) Hormone and Metabolic Research · 2013 · 9 citations
    29. The human hair follicle has established a fully functional peripheral equivalent of the hypothamalic‐pituitary‐adrenal‐axis (HPA) Experimental Dermatology · 2005 · 9 citations
    30. Qiviut cortisol reflects hypothalamic–pituitary–adrenal axis activity in muskoxen (Ovibos moschatus) General and comparative endocrinology · 2021 · 7 citations