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Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.

Patients with Bohring-Opitz syndrome and ASXL1 mutations need regular kidney ultrasounds to check for tumors.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

Burn reconstruction improves with new techniques, materials, and tissue engineering.

Minoxidil promotes hair growth by penetrating skin, with ethanol-containing formulas working best.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Using minoxidil on the scalp can help grow hair for people with hereditary baldness.

Some drugs may reduce prostatitis symptoms short-term with few side effects.

Accurate diagnosis and treatment are crucial for managing superficial fungal infections, with terbinafine being the best oral treatment for nail infections.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Malnutrition severely harms growth and development in young baboons.

Different types of PCOS have different levels of metabolic problems, with the most severe type showing the highest disturbances.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Women with PCOS are more likely to have sleep apnea, mainly if they are obese.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Metformin has limited effectiveness for improving PCOS symptoms and lacks clear benefits, needing more research to confirm its efficacy.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

South Asian women with PCOS experience more psychological distress and have a poorer quality of life, especially in social relationships, with hirsutism affecting them more than obesity.

Recognizing oral symptoms can help diagnose and treat blood and nutritional diseases early.

Botox increased hair count in men with baldness and might work by improving scalp blood flow.