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    Did you mean Melanocyte-Stimulating Hormone?
    Glossary Melanocyte-Stimulating Hormone

    regulates melanin production, affecting skin and hair pigmentation

    Melanocyte-Stimulating Hormone (MSH) is a peptide hormone produced by the pituitary gland that regulates the production of melanin, the pigment responsible for skin, hair, and eye color. It plays a crucial role in protecting the skin from UV radiation by increasing melanin synthesis, which can lead to tanning.

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    1. Reversal of premature hair graying treated with a topical formulation containing α-melanocyte-stimulating hormone agonist (Greyverse Solution 2%) International journal of trichology · 2022 · 1 citations
    2. Efficacy of an agonist of<i>α</i>-MSH, the palmitoyl tetrapeptide-20, in hair pigmentation International Journal of Cosmetic Science · 2018 · 12 citations
    3. Is seborrhea a sign of autonomic impairment in Parkinson's disease? Journal of Neural Transmission · 1997 · 46 citations
    4. Human hair follicles display a functional equivalent of the hypothalamic‐pituitary‐adrenal (HPA) axis and synthesize cortisol The FASEB Journal · 2005 · 489 citations
    5. Is There a Rationale for the Use of an Alpha-Melanocyte-Stimulating Hormone Analog to Improve Gray Hair Repigmentation? Skin Appendage Disorders · 2022
    6. Hair Follicle Immune Privilege Revisited: The Key to Alopecia Areata Management 2017 · 102 citations
    7. Alopecia areata – hyperactivity of the hypothalamic–pituitary–adrenal axis is a myth? Journal of the European Academy of Dermatology and Venereology · 2017 · 5 citations
    8. Spatiotemporal Expression, Distribution, and Processing of POMC and POMC-derived Peptides in Murine Skin Journal of Histochemistry & Cytochemistry · 2000 · 49 citations
    9. Functions of peroxisome proliferator‐activated receptors (PPAR) in skin homeostasis Lipids · 2004 · 46 citations
    10. Hormone therapy in acne Indian Journal of Dermatology, Venereology and Leprology · 2013 · 24 citations
    11. Effects of the selective TrkA agonist gambogic amide on pigmentation and growth of human hair follicles in vitro PLOS ONE · 2019 · 6 citations
    12. Hormonal treatment of acne vulgaris: an update Clinical, Cosmetic and Investigational Dermatology · 2016 · 46 citations
    13. Untersuchungen der Fremdstoffbindung in permanenten Keratinozyten- und Melanozyten-Zelllinien sowie die Eignung von Primärkulturen aus humanen Haarfollikeln zur In-vitro-Messung der Fremdstoffaufnahme im Haar Carl von Ossiezky University of Oldenburg · 2006
    14. Hair Follicle Pigmentation 2005 · 450 citations
    15. Update on Melasma—Part I: Pathogenesis Dermatology and Therapy · 2022 · 10 citations
    16. Impact of Thyroid Dysfunction on Hair Disorders Cureus · 2023
    17. Growth Hormone and the Human Hair Follicle International journal of molecular sciences · 2021 · 14 citations
    18. Human Hair Graying Revisited: Principles, Misconceptions, and Key Research Frontiers Journal of Investigative Dermatology · 2023 · 21 citations
    19. Gray Hair: From Preventive to Treatment Clinical Cosmetic and Investigational Dermatology · 2025
    20. Endocannabinoids limit excessive mast cell maturation and activation in human skin Journal of Allergy and Clinical Immunology · 2012 · 124 citations
    21. Regulated Proenkephalin Expression in Human Skin and Cultured Skin Cells 2010 · 77 citations
    22. Hair regeneration: Mechano-activation and related therapeutic approaches. PubMed · 2025
    23. Can Plant Extracts Help Prevent Hair Loss or Promote Hair Growth? A Review Comparing Their Therapeutic Efficacies, Phytochemical Components, and Modulatory Targets 2024
    24. Melasma, a photoaging disorder Pigment cell & melanoma research · 2017 · 144 citations
    25. Melanocytes and Vitiligo (and Hair Graying) Elsevier eBooks · 2014 · 1 citations
    26. The Effect of Parathyroid Hormones on Hair Follicle Physiology: Implications for Treatment of Chemotherapy-Induced Alopecia Skin Pharmacology and Physiology · 2015 · 15 citations
    27. The role of nuclear hormone receptors in cutaneous wound repair Cell Biochemistry and Function · 2014 · 68 citations
    28. Hormonal regulation in male androgenetic alopecia—Sex hormones and beyond: Evidence from recent genetic studies Experimental Dermatology · 2020 · 15 citations
    29. Topical L‐thyroxine: The Cinderella among hormones waiting to dance on the floor of dermatological therapy? Experimental Dermatology · 2020 · 9 citations
    30. Thyrotropin-Releasing Hormone (TRH) Promotes Wound Re-Epithelialisation in Frog and Human Skin PLOS ONE · 2013 · 46 citations