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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Finasteride effectively treats BPH, but needs more trials to understand potential.

Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Finasteride for hair loss can cause long-lasting sexual side effects like low libido and erectile dysfunction.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Zinc is effective for treating various skin conditions, including warts and acne.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Too much androgen can cause hair loss; finasteride may help.

Liposomes and niosomes improve finasteride delivery for hair loss treatment.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

Green tea component EGCG could potentially promote human hair growth.

Flutamide may slightly improve hair loss in women, but finasteride does not work.

Finasteride doesn't harm male fertility or sperm quality, but may slightly reduce ejaculate volume.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Dutasteride may help stabilize Frontal Fibrosing Alopecia, but more research is needed.

Polygonum multiflorum extract helps grow hair by activating certain hair growth signals in mice.

Finasteride may reduce prostate bleeding by lowering blood vessel growth factor levels and blood vessel density in certain prostate areas.

Taking 1 mg/day finasteride for hair loss significantly lowers PSA levels in men, which may affect prostate cancer screening.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Spironolactone can cause side effects like irregular bleeding, but lower doses may reduce these effects and still improve hirsutism.

New treatments for male hypogonadism are effective and should be personalized.

Finasteride reduces hair growth better, but spironolactone has more side effects.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Finasteride is a safe, effective treatment for hirsutism with fewer side effects.

Finasteride, CPA, and flutamide are all equally effective in reducing excessive hair growth in women.

Finasteride can slow hair loss and promote growth in postmenopausal women.