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Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.

A new compound effectively inhibits human 5α-reductase 1.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

Taking 5-alpha reductase inhibitors does not increase the risk of breast cancer in men.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

5-alpha reductase inhibitors increase the risk of sexual dysfunction in patients treating enlarged prostate but not in those treating hair loss.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

Certain drugs change freshwater snail shells to a "banana" shape.

Using 5-alpha reductase inhibitors may lower the risk of breast cancer in females.

Using 5α-reductase inhibitors for hair loss can cause lasting sexual, physical, mental, and vascular health issues in men, even after stopping the medication.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Taking 5α-reductase inhibitors does not significantly increase the risk of breast cancer in men.

Men taking 5-alpha-reductase inhibitors before or after bladder cancer diagnosis had a lower risk of dying from the disease.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.

Women also use 5α-reductase inhibitors, and their effects differ from men.

Certain drugs that block specific enzymes can help treat prostate diseases.

5-α-reductase inhibitors reduce prostate cancer risk but may cause sexual dysfunction and don't affect high-grade tumor or death rates.

Dutasteride works better than finasteride for hair loss, with both being safe to use.

Taking 5-Alpha Reductase Inhibitors before bladder removal surgery might make high-grade bladder tumors less aggressive.

Starting 5-alpha reductase inhibitors does not significantly increase the risk of rhabdomyolysis in older men, but is linked to a higher risk of muscle conditions.

5-alpha reductase inhibitors may reduce bladder cancer recurrence and improve survival.

Using 5-alpha-reductase inhibitors may improve bladder cancer survival in men.

Oral finasteride and dutasteride may negatively affect erectile function in rats.

New compounds were made that effectively block enzymes related to prostate issues and hair loss.

New compounds were made that effectively block a specific enzyme related to androgen conditions.