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540-570 / 1000+ resultsresearch Cell Biology and Disease of Hair Follicle: Pathomechanism and Treatment of Androgenetic Alopecia
research A Comparison of an Herbal Drug and 2% Minoxidil Solution in the Treatment of Androgenetic Alopecia
![National Lipid Association Recommendations for Patient-Centered Management of Dyslipidemia: Part 2](/images/research/b3dc63e5-1276-41eb-94b3-bea870c0f5ad/small/14212.jpg)
research National Lipid Association Recommendations for Patient-Centered Management of Dyslipidemia: Part 2
The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.
![11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors for the Treatment of Type 2 Diabetes](/images/research/227295d1-aa3a-4292-a0b6-29283b2c4d94/small/14838.jpg)
research 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors for the Treatment of Type 2 Diabetes
Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.
research Rational Design and Synthesis of 4-((1R,2R)-2-Hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a Novel, Nonsteroidal Androgen Receptor Antagonist Devoid of Phototoxicity for Dermatological Indications
PF-998425 is a new, effective, and non-phototoxic treatment for skin conditions related to androgens.
![Procyanidins Attenuate Neuropathic Pain by Suppressing Matrix Metalloproteinase-9/2](/images/research/7d9d0942-6e6b-4da3-af22-f0b5ead320bd/small/4321.jpg)
research Procyanidins Attenuate Neuropathic Pain by Suppressing Matrix Metalloproteinase-9/2
Procyanidins from grape seeds reduce nerve pain by blocking specific proteins and inflammation.
![Hair Tourniquet Syndrome of the Toe: Report of Two New Cases](/images/research/795a14df-1fa5-401d-9878-1b1417cd31ee/small/24754.jpg)
research Hair Tourniquet Syndrome of the Toe: Report of Two New Cases
Two babies needed surgery to remove hair tightly wrapped around their toes to prevent serious injury.
![Sebaceous Gland Abnormalities in Fatty Acyl CoA Reductase 2 (Far2) Null Mice Result in Primary Cicatricial Alopecia](/images/research/c4392e59-76d4-4da9-b9e2-ac327ad658b8/small/34269.jpg)
research Sebaceous Gland Abnormalities in Fatty Acyl CoA Reductase 2 (Far2) Null Mice Result in Primary Cicatricial Alopecia
Deleting the Far2 gene in mice causes sebaceous gland issues and patchy hair loss.
![Discovery of Clinically Approved Drugs Capable of Inhibiting SARS-CoV-2 In Vitro Infection Using a Phenotypic Screening Strategy and Network-Analysis to Predict Their Potential to Treat COVID-19](/images/research/f4ba69b3-3052-452e-92ca-76e6c22e9daf/small/17429.jpg)
research Discovery of Clinically Approved Drugs Capable of Inhibiting SARS-CoV-2 In Vitro Infection Using a Phenotypic Screening Strategy and Network-Analysis to Predict Their Potential to Treat COVID-19
Four drugs were found that could potentially treat COVID-19 by inhibiting the virus in lab tests.
research Pityriasis Rubra Pilaris: A Study Evaluating Patient Quality of Life in Two Populations
Pityriasis rubra pilaris significantly worsens quality of life more than many other health conditions.
![Evaluation of Risk-Minimization Activities for Cyproterone Acetate 2 mg/Ethinylestradiol 35 µg: A Cross-Sectional Physician Survey](/images/research/86a17409-52ff-40df-aca7-3f43a6e03758/small/13871.jpg)
research Evaluation of Risk-Minimization Activities for Cyproterone Acetate 2 mg/Ethinylestradiol 35 µg: A Cross-Sectional Physician Survey
Most doctors know the thrombosis risk with Cyproterone/Ethinylestradiol, but some lack details on less common risks and patient instructions; educational materials are underused but useful.
![Cutaneous Lupus Erythematosus Presenting as Frontal Fibrosing Alopecia: Report of 2 Patients](/images/research/e598d4bb-c8c9-4e54-a549-0ce26e46c022/small/18317.jpg)
research Cutaneous Lupus Erythematosus Presenting as Frontal Fibrosing Alopecia: Report of 2 Patients
Two patients with skin lupus were mistakenly thought to have a different scalp condition but improved with lupus treatment.
![Abnormal Saccadic Oscillations Associated with Severe Acute Respiratory Syndrome Coronavirus 2 Encephalopathy and Ataxia](/images/research/88c8e034-2d04-4102-9414-7826e1ba9f0b/small/12128.jpg)
research Abnormal Saccadic Oscillations Associated with Severe Acute Respiratory Syndrome Coronavirus 2 Encephalopathy and Ataxia
A man developed neurological issues from SARS-CoV-2 without severe breathing problems, worsening to death.
research Successful Treatment of Alopecia Totalis with Hydroxychloroquine: Report of 2 Cases
Hydroxychloroquine helped two people regrow hair lost from alopecia totalis.
research Epidermal Choristoma of the Oral Cavity: Report of Two Cases of an Extremely Rare Entity
![Virtual Screening of Potential Inhibitors for SARS-CoV-2 Main Protease](/images/research/7aae58c6-37f1-4ecc-a2f3-00bf34a7ad91/small/17488.jpg)
research Virtual Screening of Potential Inhibitors for SARS-CoV-2 Main Protease
The document concluded that certain compounds might strongly bind to and potentially inhibit a key SARS-CoV-2 protein, but further testing is needed.
![Transtherapy for Moderate to Severe Acne Scars: A Study of Two Cases](/images/research/4933f69e-adb6-44d1-97c2-87e24d875ab2/small/34354.jpg)
research Transtherapy for Moderate to Severe Acne Scars: A Study of Two Cases
Transtherapy significantly improved moderate to severe acne scars without side effects.
![Metabolic Effect at Six and Twelve Months of Cyproterone Acetate (2 mg) Combined with Ethinyl Estradiol (35 µg) in 31 Patients](/images/research/02723abe-20b2-41b2-8080-0840ee6fdbdb/small/21136.jpg)
research Metabolic Effect at Six and Twelve Months of Cyproterone Acetate (2 mg) Combined with Ethinyl Estradiol (35 µg) in 31 Patients
The medication combination did not affect glucose tolerance but increased some cholesterol levels due to its estrogen component.
![Discovery of 7-Methoxy-6-[4-(4-Methyl-1,3-Thiazol-2-yl)-1H-Imidazol-5-yl]-1,3-Benzothiazole (TASP0382088): A Potent and Selective Transforming Growth Factor-β Type I Receptor Inhibitor as a Topical Drug for Alopecia](/images/research/9620bd26-3366-4f2a-bcac-f511697bbc41/small/35997.jpg)
research Discovery of 7-Methoxy-6-[4-(4-Methyl-1,3-Thiazol-2-yl)-1H-Imidazol-5-yl]-1,3-Benzothiazole (TASP0382088): A Potent and Selective Transforming Growth Factor-β Type I Receptor Inhibitor as a Topical Drug for Alopecia
A new compound shows promise as a topical treatment for hair loss.
![From Bedside to Bench: Regulation of Host Factors in SARS-CoV-2 Infection](/images/research/e8eaa1ce-2411-41dd-b2cd-bc0c88d88fd7/small/13236.jpg)
research From Bedside to Bench: Regulation of Host Factors in SARS-CoV-2 Infection
The conclusion is that certain genetic factors and blood types may affect COVID-19 severity, but changes in ACE2 and TMPRSS2 genes are not clearly linked to it.
![Low Neutralizing Antibody Titers After Asymptomatic or Non-Severe SARS-CoV-2 Infection Over a 6-Month Assessment Period](/images/research/03044b8f-537a-4eda-b1ec-04a2f9626486/small/26688.jpg)
research Low Neutralizing Antibody Titers After Asymptomatic or Non-Severe SARS-CoV-2 Infection Over a 6-Month Assessment Period
People with no symptoms or mild COVID-19 have lower antibody levels, increasing their risk of getting COVID-19 again.
![Generalized Hypertrichosis Associated with the Use of Interleukin 17 Blockers in 2 Patients with Psoriasis](/images/research/af480607-adb6-467a-a7c7-582a2f87d886/small/17441.jpg)
research Generalized Hypertrichosis Associated with the Use of Interleukin 17 Blockers in 2 Patients with Psoriasis
Two patients with psoriasis grew extra hair after using certain psoriasis medications.
![The Synthesis of (−)-4-Methyl-8-Chloro-Trans-1,2,3,4,4a,5,6,10b-Octahydrobenzo-[f]-Quinolin-3-One-[3-14C] (LY300502-14C) via a Circuitous Route](/images/research/73bab8dc-bdf0-45e3-8ef7-73d0d4b93cb1/small/21074.jpg)
research The Synthesis of (−)-4-Methyl-8-Chloro-Trans-1,2,3,4,4a,5,6,10b-Octahydrobenzo-[f]-Quinolin-3-One-[3-14C] (LY300502-14C) via a Circuitous Route
Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.
![Platelet-Rich Plasma with Low Dose Oral Minoxidil (1.25 mg Versus 2.5 mg) Along with Trichoscopic Pre- and Post-Treatment Evaluation](/images/research/7118b823-55bb-4e02-900e-d79ef943ab50/small/12044.jpg)
research Platelet-Rich Plasma with Low Dose Oral Minoxidil (1.25 mg Versus 2.5 mg) Along with Trichoscopic Pre- and Post-Treatment Evaluation
Combining platelet-rich plasma therapy with low dose oral minoxidil improved hair growth in men with hair loss, with slightly higher satisfaction at the higher minoxidil dose.
![Comparative Study of the Efficacy and Safety of Topical Minoxidil 2% Versus Topical Bimatoprost 0.01% Versus Topical Bimatoprost 0.03% in Treatment of Eyebrow Hypotrichosis: A Randomized Controlled Trial](/images/research/bc58cf9b-48ec-4937-9444-f6d27b6c2b0a/small/36087.jpg)
research Comparative Study of the Efficacy and Safety of Topical Minoxidil 2% Versus Topical Bimatoprost 0.01% Versus Topical Bimatoprost 0.03% in Treatment of Eyebrow Hypotrichosis: A Randomized Controlled Trial
Bimatoprost 0.03% is as effective as minoxidil 2% for eyebrow growth.
![The Clinical Course and Outcomes of SARS-CoV-2 Virus Infection in Children: A 24-Week Follow-Up Study in Sulaimaniyah, Iraq](/images/research/dfb7d950-b628-4cd3-9d67-3946311fa1da/small/23538.jpg)
research The Clinical Course and Outcomes of SARS-CoV-2 Virus Infection in Children: A 24-Week Follow-Up Study in Sulaimaniyah, Iraq
Most children recovered from COVID-19 in 4 weeks, but some experienced long-term symptoms, especially older kids.
research OsCSLD1 Mediates NH4+-Dependent Root Hair Growth Suppression and AMT1;2 Expression in Rice
CSLD1 suppresses rice root hair growth with NH4+ and regulates AMT1;2 expression.
![Response to Baricitinib in the Treatment of Patients with Early and Late Onset Alopecia Areata in the Phase 2 Portion of BRAVE-AA1 Randomized Controlled Trial](/images/research/3f7f8422-c008-4126-9751-a3a251e4d0bc/small/23347.jpg)
research Response to Baricitinib in the Treatment of Patients with Early and Late Onset Alopecia Areata in the Phase 2 Portion of BRAVE-AA1 Randomized Controlled Trial
Baricitinib was effective in treating both early and late onset alopecia areata.
![A Practitioner's Guide to Hair Loss: Part 2—Diet, Supplements, Vitamins, Minerals, Aromatherapy, and Psychosocial Aspects](/images/research/ae838a04-00a8-405a-8c44-81d96934f524/small/28732.jpg)
research A Practitioner's Guide to Hair Loss: Part 2—Diet, Supplements, Vitamins, Minerals, Aromatherapy, and Psychosocial Aspects
Non-drug methods like diet, supplements, and aromatherapy can help manage hair loss and its emotional impact.